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001-es BibID:	BIBFORM125832
Első szerző:	Csehely Szilvia (szülész-nőgyógyász szakorvos)
Cím:	Primary hyperparathyroidism recognised in pregnancy / Szilvia Csehely, Klaudia Balog, Roland Fedor, Mónika Andrási, Peter Damjanovich, Tamás Deli, Endre Nagy, Sándor Barna, Ferenc Győri, Miklós Bodor, Attila Jakab
Dátum:	2020
Megjegyzések:	Hyperparathyreodism is a rare condition, and has added risk if present in pregnancy. Management requires high expertise. Primary hyperparathyroidism diagnosed in pregnany is uncommon and is most often due to a solitary parathyroid adenoma. It is usually asymptomatic, since symptoms of hypercalcemia may be difficult to diagnosis, as they are frequently similar to those of pregnancy, such as nausea, fatigue and vomiting. Pregnant women with hyperparathyreodism has a significantly higher risk for obstetrical complications, but what is more important, the life of the fetus is in danger. The risk of early spontaneous abortion is elevated, which correlates with maternal serum calcium levels. The highest risk for fetal demise is at very high Ca-levels (above 12mg/dl), risk is up to 85% at 13 mg/dl Ca-levels. Early recognition and treatment are crucial to preventing long-term or lethal consequences. If is not recognised in time or untreated it can result in maternal preecclampsia, there might be cardiac arrythmia during labor, and preterm birth, IUGR, fetal demise is also more common. If the fetal parathyroid glands are fail to develop normally, permanent hypoparathyreodism might be present at the fetus, and postnatal hypocalcemic tetany might occur to the newborn. We present a case of primary hyperparathyroidism due to a parathyroid adenoma in a 28-year-old G1P0 pregnant women who was diagnosed by routine laboratory result at the 7th gestational week. Urgent parathyroidectomy was required. The successful management of the patient was possible with an intensive collaboration of obstetrician, endocrinologist, surgeon, and anaesthesiologist.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk primary hyperparathyroidism pregnancy
Megjelenés:	Gynecological and Reproductive Endocrinology & Metabolism (2020). - Supplement 1 (2020), p. 490. -
További szerzők:	Balog Klaudia (1988-) (sebész szakorvos) Fedor Roland (1975-) (sebész) Andrási Mónika Damjanovich Péter Gábor (1985-) (szülész-nőgyógyász) Deli Tamás (1979-) (szülész-nőgyógyász, endokrinológus szakorvos) Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Barna Sándor (1982-) (kutató orvos) Győri Ferenc Bodor Miklós (1969-) (belgyógyász, endokrinológus) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus)
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001-es BibID:	BIBFORM065478
Első szerző:	Csenteri Orsolya Karola (népegészségügyi ellenőr, rehabilitációs szakember)
Cím:	The role of hyperinsulinemia as a cardiometabolic risk factor independent of obesity in polycystic ovary syndrome / Orsolya Karola Csenteri, János Sándor, Edit Kalina, Harjit Pal Bhattoa, Sándor Gődény
Dátum:	2017
ISSN:	0951-3590
Megjegyzések:	The aim of this study was to utilize various insulin resistance measuring methods to determinewhether insulin resistance and other parameters impact the serum lipid levels of polycysticovary syndrome (PCOS) patients and how the serum lipid levels in these patients are affectedby the body mass index (BMI). Our dataset included patients between the ages of 16 and 42(N?228) from the outpatient endocrinology clinic of the Department of Obstetrics andGynecology, who demonstrated increased hair growth and bleeding disorders and came for aroutine oral glucose tolerance test (OGTT). Differences in the serum lipid levels were evaluatedby t-test and linear regression analysis after adjusting for BMI. A stepwise regression model wasconstructed to evaluate the influence of each variable on the lipid levels. In PCOS patients, wefound that dyslipidemia is more prevalent among hyperinsulinemic women compared withnormoinsulinemic women, even after normalizing for BMI. PCOS patients with insulinresistance, determined by the insulin sensitivity index (ISI) method, showed more significantlipid abnormalities such as low high-density lipoprotein (HDL) and apo-A levels and high totalcholesterol, low-density lipoprotein (LDL) and apo-B levels than if insulin resistance (IR)determination was based on insulin level or homeostatic model assessment (HOMA).
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban cardiovascular risk insulin resistance Obesity polycystic ovary syndrome
Megjelenés:	Gynecological Endocrinology 33 : 1 (2017), p. 34-38. -
További szerzők:	Sándor János (1966-) (orvos-epidemiológus) Kalina Edit (1971-) (laboratóriumi analitikus) Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Gődény Sándor (1951-) (nőgyógyász, egészségügyi minőségbiztosítási szakember)
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001-es BibID:	BIBFORM010015
Első szerző:	Németh Hajnalka (orvos)
Cím:	Autoimmune progesterone dermatitis diagnosed by intravaginal progesterone provocation in a hysterectomised woman / Németh Hajnalka, Kovács Erzsébet, Gödény Sándor, Simics Enikő, Pfliegler György
Dátum:	2009
ISSN:	0951-3590
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban progesterone dermatitis vaginal provocation gonadortopine-analogue ovulation supression
Megjelenés:	Gynecological Endocrinology. - 25 : 6 (2009), p. 410-412. -
További szerzők:	Kovács Erzsébet (1976-) (belgyógyász) Gődény Sándor (1951-) (nőgyógyász, egészségügyi minőségbiztosítási szakember) Simics Enikő (bőrgyógyász) Pfliegler György (1949-) (belgyógyász, hematológus, labor szakorvos)
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001-es BibID:	BIBFORM127938
Első szerző:	Vida Beáta (szülész-nőgyógyász)
Cím:	Swyer syndrome : a rare form of genetic-based primary ovarian insufficiency / Vida Beáta
Dátum:	2020
Megjegyzések:	Primary ovarian insufficiency (POI) is a condition, which is characterized by amenorrhea, progressive symptoms of estrogen deficiency, and elevated serum gonadotropin levels in cases of young women under 40. Genetic, autoimmune, metabolic, iatrogenic disorders are the most frequent, identifiable causes of POI. One of the most common chromosomal anomalies associated with POI is Turner syndrome, but other rare genetic-based POI are known as well, like Swyersyndrome/46,XY complete gonadal dysgenesis. The aim of the examination was to identify patients with Swyer-syndrome, and to compare them with other patients with 46,XY karyotype. Between January 2005 and December 2019 thirteen patients were registered with 46,XY karyotype at the Department of Obstetrics and Gynaecology, University of Debrecen. During the examination first signs and symptoms; blood test results, especially LH, FSH, E2, T levels; ultrasound examination results; surgical interventions; and therapy methods were collected. We registered eight patients diagnosed with Swyer-syndrome, and five patients diagnosed with complete type of AIS (C-AIS), which is also called as Morris-syndrome in the scientific literature. First signs were delayed puberty and primary amenorrhea in both groups, but in the group of Swyer-syndrome withdrawal bleeding could be induced by using medical treatment. During the speculum examination vagina and cervix were visible in this group, and in contrast with patients with C-AIS uterus and vagina were verified with ultrasound. According to the laparoscopic operation streak gonads were found in the pelvic cavity. In the group of C-AIS patients we registered inguinal or abdominal testes and the absence of uterus with ultrasound, which was confirmed with gonad biopsy. Besides these signs clitoromegaly and/or short blind-ending vagina was visible during the gynaecological examination. The clinical management of patients with 46, XY karyotype includes hormone-replacement therapy and surgical intervention mainly because of the gonad biopsy considering the possible gonadectomy. In addition to these, other treatment methods can be applied in the therapy of either Swyer syndrome or C-AIS. It is important to separate these disorders because of the exact diagnosis and targeted therapy. The most important differences between the above mentioned conditions will be presented with some clinical cases.
Tárgyszavak:	Orvostudományok Egészségtudományok idézhető absztrakt folyóiratcikk
Megjelenés:	Gynecological and Reproductive Endocrinology and Metabolism. - 1 : Suppl. 1 (2020), p. 366. -
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