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001-es BibID:	BIBFORM095684
035-os BibID:	(WoS)000635685600001 (Scopus)85103399984
Első szerző:	Kešnerová, Petra
Cím:	Peripheral Vascular Resistance in Cerebral Arteries in Patients With Carotid Atherosclerosis - Substudy Results of the Atherosclerotic Plaque Characteristics Associated with a Progression Rate of the Plaque and a Risk of Stroke in Patients With the Carotid Bifurcation Plaque Study (ANTIQUE) / Petra Kešnerová, David Školoudík, Roman Herzig, David Netuka, Istvan Szegedi, Kateřina Langová, ANTIQUE Trial Group
Dátum:	2022
ISSN:	0278-4297
Megjegyzések:	Objectives Transcranial color-coded duplex sonography (TCCS) enables to measure blood flow characteristics in cerebral vessels, including vascular resistance and pulsatility. The study aims to identify factors influencing pulsatility (PI) and resistance (RI) indices measured using TCCS in patients with carotid atherosclerosis. Methods Self-sufficient patients with atherosclerotic plaque causing 20-70% carotid stenosis were consecutively enrolled to the study. All patients underwent duplex sonography of cervical arteries and TCCS with measurement of PI and RI in the middle cerebral artery, neurological, and physical examinations. Following data were recorded: age, gender, height, weight, body mass index, systolic and diastolic blood pressure, occurrence of current and previous diseases, surgery, medication, smoking, and daily dose of alcohol. Univariant and multivariant logistic regression analysis were used for identification of the factors influencing RI and PI. Results Totally 1863 subjects were enrolled to the study: 139 healthy controls (54 males, age 55.52 +/- 7.05 years) in derivation cohort and 1724 patients (777 males, age 68.73 +/- 9.39 years) in validation cohort. The cut off value for RI was 0.63 and for PI 1.21. Independent factors for increased RI/PI were age (odds ratio [OR] = 1.108/1.105 per 1 year), occurrence of diabetes mellitus (OR = 1.767/2.170), arterial hypertension (OR = 1.700 for RI only), width of the carotid plaque (OR = 1.260 per 10% stenosis for RI only), and male gender (OR = 1.530 for PI only; P <.01 in all cases). Conclusions The independent predictors of increased cerebral arterial resistance and/or pulsatility in patients with carotid atherosclerosis were age, arterial hypertension, diabetes mellitus, carotid plaque width, and male gender.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Journal Of Ultrasound In Medicine. - 41 : 1 (2022), p. 237-246. -
További szerzők:	Školoudík, David (1968-) Herzig, Roman (1968-) Netuka, David (1968-) Szegedi István (1992-) (orvos) Langová, Kateřina (1968-) (Általános orvos) ANTIQUE Trial Group
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001-es BibID:	BIBFORM075686
Első szerző:	Kozma Bence (szülész-nőgyógyász)
Cím:	Association between pelvic organ prolapse types and levator-urethra gap as measured by 3D transperineal ultrasound / Bence Kozma, Kindra Larson, Lauren Scott, Tina D. Cunningham, Alfred Abuhamad, Robert Poka, Peter Takacs
Dátum:	2018
ISSN:	0278-4297
Megjegyzések:	Objectives : To evaluate the association between pelvic organ prolapse (POP)types and levator-urethra gap (LUG) as measured by 3-dimensional transperineal tomographic ultrasound. Methods : A retrospective study was carried out on 98 women with symptomatic POP. Three-dimensional transperineal tomographic ultrasound images and POP quantification coordinates were reviewed. Each vaginal compartment was staged for the degree of prolapse, and total number of involved compartments identified. LUG was measured on 3-dimensional tomographic sonograms as the distance between the center of the urethra and the levator insertion bilaterally. Based on prior studies, an abnormal LUG of 25mm or greater indicated levator avulsion. The LUG and the presence or absence of unilateral/bilateral avulsions was analyzed with reference to the clinical diagnosis of prolapse (single versus multicompartment, and mild [stage II] versus severe [stage III?IV]). Generalized logit models were used to evaluate the association between avulsion and prolapse type and stage. Results ? The LUG was substantially larger in women with multicompartment compared to single-compartment POP (28.964.1mm versus 22.764.1mm, P<.01). Similarly, LUG was substantially larger in women with severe (stage III?IV) compared to mild (stage II) POP (28.864.7mm versus 23.364.5 mm, P<.01). Women with severe prolapse were 32 times more likely than women with mild prolapse to have bilateral levator avulsion. Those with POP involving all 3 vaginal compartments were 76 times more likely than single-compartment POP to have bilateral levator avulsions. Conclusions : Bilateral levator ani avulsion as diagnosed by LUG measurements of 25mm or greater at rest is associated with multicompartment, severe prolapse.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban levator ani avulsion levator-urethra gap pelvic organ prolapse transperineal ultrasound
Megjelenés:	Journal Of Ultrasound In Medicine. - 37 : 12 (2018), p. 2849-2854. -
További szerzők:	Larson, Kindra Scott, Lauren Cunningham, Tina D. Abuhamad, Alfred Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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001-es BibID:	BIBFORM017679
Első szerző:	Magyar Mária Tünde (neurológus)
Cím:	Serum cholesterols have a more important role than triglycerides in determining intima-media thickness of the common carotid artery in subjects younger than 55 years of age / Magyar M. T., Paragh G., Katona E., Valikovics A., Seres I., Csiba L., Bereczki D.
Dátum:	2004
Megjegyzések:	The role of serum cholesterol and triglycerides in carotid artery atherosclerosis is controversial. We measured carotid artery intima-media thickness (IMT), a marker of atherosclerosis in subjects younger than 55 years of age with a 6-fold range of serum cholesterol levels (3.93-25.03 mmol/L) and a 200-fold range of triglyceride levels (0.36-75.97 mmol/L). METHODS: Eighty-six patients with increased serum lipid values and 30 subjects with normal lipid values were included. Serum lipids were measured after an overnight fast. High-resolution sonographic investigations of the carotid arteries of all patients were videotaped. Intima-media thickness was measured offline at 1-mm increments in the distal 10-mm segments of both common carotid arteries by a reader blinded to patient characteristics. First, IMT was compared among groups defined by their cholesterol and triglyceride levels with the use of traditional cutoff values. Next, all subjects were pooled, and general regression analysis was performed to identify significant predictors of IMT with age, body mass index, lipid values, sex, diabetes, hypertension, and smoking status as independent variables. RESULTS: Intima-media thickness was larger in patient groups with high cholesterol levels (ie, the hypercholesterolemic and combined hyperlipidemic groups) than in the control, borderline, and isolated hypertriglyceridemic groups (P < .01). In the general multiple regression model, IMT correlated positively with total cholesterol level (beta = 0.343; P = .002) and age (beta = 0.3; P = .006) but not with triglyceride level. CONCLUSIONS: Both the group comparisons and the general regression analysis of the pooled data suggest that hypercholesterolemia has an important role in early onset IMT changes in the common carotid artery, whereas hypertriglyceridemia does not have an appreciable role.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Journal Ultrasound Medicine. - 23 : 9 (2004), p. 1161-1169. -
További szerzők:	Paragh György (1953-) (belgyógyász) Katona Evelin (1974-) (belgyógyász) Valikovics Attila Seres Ildikó (1954-) (biokémikus) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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