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1.

001-es BibID:BIBFORM135285
035-os BibID:(WoS)001670700100001 (Scopus)105028560071
Első szerző:Ahmed, Omar Abdel-Fattah
Cím:Respiratory and related comorbidities` role in the risk of acute sinusitis: a 15-year longitudinal clinical study / Omar Abdel-Fattah Ahmed, Amr Sayed Ghanem, Marianna Móré, Attila Csaba Nagy
Dátum:2026
ISSN:2077-0383
Megjegyzések:Background/Objectives: Acute sinusitis (AS) is a common infection of the upper respiratory tract that places considerable clinical and economic burden worldwide. Although frequently encountered in practice, the factors that predispose individuals to AS remain poorly understood. This study examined how different respiratory disorders and comorbidities influence the likelihood of developing AS, aiming to clarify its underlying risk profile. Methods: A longitudinal analysis was performed using electronic health records from the Clinical Center of the University of Debrecen Hospital. The study cohort (2007?2022) encompassed 37,164 observations. To evaluate the risk of AS progression, Log-Rank tests and Cox proportional hazards regressions were applied whilst adjusting for covariates. Results: The risk of developing AS was significantly higher among individuals with preceding respiratory conditions. Patients with common cold demonstrated a 2.3-fold increased risk of developing AS (95% CI [1.51?3.40]). Compared to those without such disorders, participants with acute bronchitis had a 2.5-fold higher hazard of AS (95% CI 1.90?3.26). The strongest association was observed for allergic rhinitis (HR = 4.04, 95% CI 3.18?5.13), followed by chronic sinusitis (HR = 3.10, 95% CI 2.13?4.51). Chronic obstructive pulmonary disease was also identified as a significant predictor for AS (HR = 1.62, 95% CI 1.04?2.52), whereas dental pathologies were associated with a modest protective effect (HR = 0.69, 95% CI 0.48?0.97). Conclusions: Patients with allergic rhinitis, chronic sinusitis, acute bronchitis, common cold, or chronic obstructive pulmonary disease have a markedly higher risk of developing AS. Clinicians should actively screen for these conditions when assessing patients with recurrent or severe sinus infections. Early recognition and management of underlying respiratory disorders may reduce AS episodes, promote symptom control, and lessen healthcare burdens. Future research should concentrate on precision medicine to leverage AS preventive and management strategies.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
respiratory
comorbidities
sinusitis
infection
allergic rhinitis
asthma
COPD
cohort
clinical
epidemiology
Megjelenés:Journal of Clinical Medicine. - 15 : 2 (2026), p. 1-16. -
További szerzők:Ghanem, Amr Sayed (1991-) (orvos, fogorvos) Móré Marianna (1959-) (társadalomkutató) Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
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2.

001-es BibID:BIBFORM133511
Első szerző:Bata Róbert (informatikus)
Cím:Feature Selection and Model Optimization for Survival Prediction in Patients with Angina Pectoris / Bata Róbert, Ghanem Amr Sayed, Nagy Attila Csaba
Dátum:2025
ISSN:2077-0383
Megjegyzések:With the rapid emergence of novel survival models and feature selection methods, comparing them with traditional approaches is essential to define contexts of optimal performance. Methods: This study systematically evaluates nine survival models combined with nine feature selection methods for predicting the occurrence of angina pectoris using electronic health record (EHR) data from a Hungarian hospital (n = 29,655, features = 1150). Performance was assessed with the concordance index (C-index) and integrated Brier score (IBS) to compare predictive accuracy across methods. Results: Tree-based survival models, particularly gradient-boosted survival (GBS) and random survival forest (RSF), consistently outperformed conventional approaches in terms of C-index, but showed slightly worse calibration as reflected in their higher IBSs. The best-performing model was RSF, which was optimized using Bayesian hyperparameter tuning. For feature selection, tree-based methods such as Boruta and RSF-based approaches showed superior performance. We further identified clusters of feature selection methods and generated consensus feature sets. We also analyzed the internal relationships between the selected features. Survival model performance was also examined over time using the time-dependent Area Under the Curve (AUC) based on the best-performing feature set. Conclusions: Our findings highlight the substantial impact of recent methodological innovations in survival analysis, which offer significant gains in predictive accuracy and efficiency, ultimately support more robust clinical decision-making in the early identification of angina pectoris among patients with diabetes.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
survival analysis
machine learning
feature selection
EHR
comparative study
angina pectoris
type 2 diabetes mellitus
Megjelenés:Journal of Clinical Medicine. - 14 : 22 (2025), p. 1-20. -
További szerzők:Ghanem, Amr Sayed (1991-) (orvos, fogorvos) Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
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3.

001-es BibID:BIBFORM132070
Első szerző:Diószegi Ágnes (belgyógyász)
Cím:Assessment of Serum Endocan Levels and Their Associations with Arterial Stiffness Parameters in Young Patients with Systemic Lupus Erythematosus / Diószegi Ágnes, Lőrincz Hajnalka, Kaáli Eszter, Csiha Sára, Kaluha Judit, Varga Éva, Páll Dénes, Tarr Tünde, Harangi Mariann
Dátum:2025
ISSN:2077-0383
Megjegyzések:Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder associated with premature atherosclerosis and vascular impairment. However, the role of endocan, a biomarker of glycocalyx injury, is not completely clarified in the detection of vascular damage. Therefore, our aim was to investigate serum endocan in comparison with conventional inflammatory markers, arterial stiffness parameters, and carotid ultrasound findings in a cohort of young patients with SLE. Methods: We enrolled 47 clinically active young SLE patients (40 females and 7 males) in the study. Arterial stiffness indicated by augmentation index and pulse wave velocity (PWV) was measured by arteriography. Brachial artery flow-mediated dilatation and common carotid intima-media thickness were detected by ultrasonography. The serum concentrations of endocan, IL-6, MPO, MCP-1, MMP-3, -7, and -9, as well as TNF?, were measured by an enzyme-linked immunosorbent assay (ELISA). Results: We found significant negative correlations between serum endocan and both CH50 and C3. Serum endocan was higher in active SLE patients compared to inactive patients, however, the difference was not statistically significant (241.4 (183?295) vs. 200.3 (167?278) pg/mL; p = 0.313). Serum TNF? and hsCRP significantly correlated with PWV. However, we did not detect significant correlations between vascular diagnostic tests and serum endocan levels. Conclusions: Based on our results, serum endocan is associated with disease activity; however, further studies are needed to clarify the value of serum endocan in the cardiovascular risk estimation of SLE patients. Measurement of serum endocan, as well as the routine assessment of arterial stiffness parameters, should be integrated into the comprehensive management plans of young patients with SLE.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
endocan
tumor necrosis factor-alpha
C-reactive protein
atherosclerosis
systemic lupus erythematosus
arterial stiffness
pulse wave velocity
Megjelenés:Journal of Clinical Medicine. - 14 : 17 (2025), p. 1-16. -
További szerzők:Lőrincz Hajnalka (1986-) (biológus) Kaáli Eszter Csiha Sára (1985-) (Biológus) Kaluha Judit (1987-) (orvos) Varga Éva (1982-) (belgyógyász) Páll Dénes (1967-) (belgyógyász, kardiológus) Tarr Tünde (1976-) (belgyógyász, allergológus és klinikai immunológus) Harangi Mariann (1974-) (belgyógyász, endokrinológus)
Pályázati támogatás:OTKA - 142273
OTKA
TKP2021-EGA-18
Egyéb
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4.

001-es BibID:BIBFORM128725
035-os BibID:(WoS)001334248100001 (Scopus)85206578870
Első szerző:Hudák Lilla (neurológus)
Cím:Clinicopathological Observations in Acute Stroke Patients Treated with Intravenous Thrombolysis / Lilla Hudák, Kitti Bernadett Kovács, Zsuzsa Bagoly, István Szegedi, Viktor Bencs, Linda Lóczi, Rita Orbán-Kálmándi, Henrietta Péter-Pakó, Zsófia Fülesdi, Blanka Busi, Attila Nagy, Beáta Perjési-Kiss, László Oláh, László Csiba
Dátum:2024
ISSN:2077-0383
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal of Clinical Medicine. - 13 : 19 (2024), p. 1-11. -
További szerzők:Kovács Kitti Bernadett (1985-) (neurológus) Bagoly Zsuzsa (1978-) (orvos) Szegedi István (1969-) (hematológus, onkológus, nefrológus) Bencs Viktor (1995-) (orvos) Lóczi Linda (1993-) Orbán-Kálmándi Rita Angéla (1993-) (klinikai laboratóriumi kutató) Péter-Pakó Henrietta Fülesdi Zsófia (1990-) (radiológus) Busi Blanka Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus) Perjési-Kiss Beáta Oláh László (1967-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter)
Pályázati támogatás:MTA-DE Lendület
MTA
Élettudományok - Orvosi tudományok
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5.

001-es BibID:BIBFORM126415
035-os BibID:(scopus)85214474919 (wos)001395067200001
Első szerző:Martos Renáta (fogszakorvos)
Cím:Effects of Combined Periodontal, Endodontic, and Dentoalveolar Surgical Treatments on Laboratory Parameters in Patients with Hyperlipidemia : A Clinical Interventional Study / Martos Renáta, Harangi Mariann, Szabó Judit, Földvári Anett, Sándor János, Katona Éva, Tar Ildikó, Paragh György, Kiss Csongor, Márton Ildikó
Dátum:2025
ISSN:2077-0383
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal of Clinical Medicine. - 14 : 1 (2025), p. 1-16. -
További szerzők:Harangi Mariann (1974-) (belgyógyász, endokrinológus) Szabó Judit (1963-) (szakorvos, klinikai mikrobiológus) Földvári Anett (1984-) (népegészségügyi felügyelő) Sándor János (1966-) (orvos-epidemiológus) Katona Éva (1961-) (klinikai biokémikus) Tar Ildikó (1967-) (fogszakorvos) Paragh György (1953-) (belgyógyász) Kiss Csongor (1956-) (hematológus, onkológus) Márton Ildikó (1954-) (fogszakorvos)
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6.

001-es BibID:BIBFORM133501
Első szerző:Nádró Bíborka (általános orvos)
Cím:Diagnostic and Therapeutic Challenges of Homozygous and Severe Heterozygous Familial Hypercholesterolemia from Clinical Aspect : A Single-Center Study / Nádró Bíborka, Kaluha Judit, Lőrincz Hajnalka, Varga Éva, Balogh István, Harangi Mariann
Dátum:2025
ISSN:2077-0383
Megjegyzések:Background/Objectives: The clinical presentation of homozygous familial hypercholesterolemia (HoFH) and severe heterozygous familial hypercholesterolemia (sHeFH) often demonstrates substantial overlap, as low-density lipoprotein cholesterol (LDL-C) levels may fall within similar ranges in both conditions. Methods: In this single-center 10-year retrospective study at the University of Debrecen, Hungary, we present the clinical characteristics of patients with 6 HoFH and 6 sHeFH diagnosed by genetic testing, discuss the diagnostic limitations encountered in clinical practice, and outline the key components of therapeutic management. Results: The mean age at diagnosis was lower in the HoFH group (31.83 ? 19.5 vs. 41.83 ? 15.9 years). The differences in total cholesterol (13.48 ? 7.4 vs. 11.02 ? 3.5 mmol/L) and LDL-C levels (10.89 ? 6.6 vs. 8.58 ? 3.26 mmol/L) between the groups were not statistically significant. Interestingly, vascular complications were more frequent in sHeFH group as well (4 vs. 1 patients). In neither the HoFH nor the sHeFH group were we able to achieve the target LDL-C levels, due in part to the specific features of the reimbursement system, patient and parental preferences, the extremely high baseline LDL-C levels, and certain genetic characteristics. Conclusions: Our findings highlight the importance of genetic testing-based personalized therapy in these specific patient subpopulations. We emphasize that serum LDL-C alone is insufficient to distinguish between HoFH and sHeFH patients, and that therapeutic challenges should be anticipated in both groups arising partly from limited patient adherence as well as from financial constraints.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
familial hypercholesterolemia
homozygous
heterozygous
low-density lipoprotein cholesterol
genetic testing
lipid-lowering therapies
therapy resistance
personalized medicine
Megjelenés:Journal of Clinical Medicine. - 14 : 22 (2025), p. 1-15. -
További szerzők:Kaluha Judit (1987-) (orvos) Lőrincz Hajnalka (1986-) (biológus) Varga Éva (1982-) (belgyógyász) Balogh István (1972-) (molekuláris biológus, genetikus) Harangi Mariann (1974-) (belgyógyász, endokrinológus)
Pályázati támogatás:K142273
OTKA
TKP2021-EGA-18
Egyéb
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7.

001-es BibID:BIBFORM125855
035-os BibID:(Scopus)85211803986 (WoS)001376524400001
Első szerző:Nagy Attila Csaba (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
Cím:Protective Influence of SGLT-2 Inhibitors Against Heart Failure in Type 2 Diabetes Mellitus Through Longitudinal Clinical Database Analysis / Attila Csaba Nagy, Ágnes Tóth, Natália Bak, Battamir Ulambayar, Amr Sayed Ghanem, Ferenc Sztanek
Dátum:2024
ISSN:2077-0383
Megjegyzések:Background: Sodium?glucose co-transporter 2 (SGLT-2) inhibitors, initially designed for type 2 diabetes, promote glucose excretion and lower blood glucose. Newer analogs like empagliflozin and dapagliflozin improve cardiovascular outcomes through mechanisms other than glycemic control, including blood pressure reduction and anti-inflammatory effects. Given the high cardiovascular risk present in diabetes, our study aims to emphasize the cardioprotective benefits of SGLT-2 inhibitors as a preventive therapy for heart failure (HF) in high-risk T2DM patients. Methods: Using data from 2542 patients identified by the ICD-10 E11 code from 2016 to 2020, this longitudinal study excluded those with E10 codes or those undergoing insulin treatment to focus on non-insulin-dependent T2DM. a multiple logistic regression model assessed HF incidence while adjusting for demographics and HbA1c. Results: SGLT-2 inhibitor use significantly lowered the odds of heart failure events (OR = 0.55, 95% CI: 0.31?0.99, p = 0.046), with a significant difference by gender (OR = 0.45, 95% CI: 0.28?0.71, p = 0.001) and eGFR (OR = 0.98, 95% CI: 0.97?0.99, p = 0.004). Conclusions: The real-world data highlight SGLT-2 inhibitors as promising for HF prevention and broader cardiometabolic health in T2DM, with potential value in managing complex comorbid profiles.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
diabetes mellitus
cardiovascular disease
heart failure
SGLT-2 inhibitors
clinical laboratory tests
Megjelenés:Journal of Clinical Medicine. - 13 : 23 (2024), p. 1-11. -
További szerzők:Tóth Ágnes (1983-) (biofizikus) Bak Natália Ulambayar, Battamir (1986-) (orvos) Ghanem, Amr Sayed (1991-) (orvos, fogorvos) Sztanek Ferenc (1982-) (orvos)
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8.

001-es BibID:BIBFORM129928
035-os BibID:(WoS)001496704400001 (Scopus)105006669489
Első szerző:Szinay Dorottya (Orvos)
Cím:Assessment of Efficacy and Safety of Lipid-Lowering Treatment and Its Importance in Risk Assessment and Prevention in a Hungarian Myositis Cohort / Dorottya Szinay, Katalin Szabó, Henrik Molnár, Tibor Béldi, Viktor Bencs, Hajnalka Lőrincz, Mariann Harangi, Zoltán Griger, Melinda Nagy-Vincze
Dátum:2025
ISSN:2077-0383
Megjegyzések:Background: Idiopathic inflammatory myopathies (IIMs), also known as myositis, are systemic autoimmune diseases characterized by chronic inflammation affecting the skin, muscles, and internal organs. Besides traditional risk factors and immune-mediated myocarditis, continuous activity of the immune system increases cardiovascular disease (CVD) risk, meaning that cardiovascular events are the leading causes of mortality in IIM patients. Statins are the most widely used lipid-lowering therapies, which reduce cardiovascular risk, but the fear of adverse muscular events inhibits the frequency of use. Methods: Our aim was to assess the CVD risk in a myositis cohort using the SCORE2 prediction system, carotid artery Doppler ultrasound measurement, and biomarkers; recommend individual lipid-lowering treatment; and follow the efficacy and adverse events of therapy in a 6-month treatment period. Results: The study population (80 IIM patients) was a middle-aged, female-dominant myositis cohort with an average disease duration of 9 years and low median global disease activity. Based on the SCORE2 evaluation, 78.8% of patients had medium/high CVD risk, while 73.13% had asymptomatic carotid plaque. After 6 months of adequate lipid-lowering therapy, 37.5% of patients reached a lower CVD risk category, the biomarker levels of atherosclerosis significantly decreased, and no progression in carotid plaques was detected. None of the patients reported an adverse muscular event or IIM relapse. Conclusions: Our findings proved that the CVD risk of patients with myositis is high, but carefully applied lipid-lowering treatment is the key to effective risk reduction. Risk stratification and the recommendation of preventive treatment are the responsibility of the treating physician.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
idiopathic inflammatory myopathies
cardiovascular disease risk
statin
efficacy
Megjelenés:Journal of Clinical Medicine. - 14 : 10 (2025), p. 1-18. -
További szerzők:Szabó Katalin (1991-) (orvos) Molnár Henrik Béldi Tibor (1994-) (orvos) Bencs Viktor (1995-) (orvos) Lőrincz Hajnalka (1986-) (biológus) Harangi Mariann (1974-) (belgyógyász, endokrinológus) Griger Zoltán (1979-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Nagy-Vincze Melinda (1985-) (orvos)
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9.

001-es BibID:BIBFORM131910
Első szerző:Sztanek Ferenc (orvos)
Cím:Sex Differences in Cardiovascular Risk and Diabetic Polyneuropathy : a Single-Center Retrospective Study in North-Eastern Hungary / Sztanek Ferenc, Pető Attila, Tóth László Imre, Lőrincz Hajnalka, Molnár Ágnes, Lukács Miklós, Menyhárt Adrienn, Kempler Péter, Paragh György, Harangi Mariann, Nagy Attila Csaba
Dátum:2025
ISSN:2077-0383
Megjegyzések:Background/Objectives: Diabetic sensorimotor polyneuropathy (DSPN) is a frequent microvascular complication of diabetes mellitus, associated with increased morbidity and reduced quality of life. The existing literature offers a limited understanding of sex-specific cardiovascular risk profiles and their association with DSPN, particularly within Central and Eastern European populations. Methods: A retrospective analysis was conducted using data from 621 individuals with type 1 or type 2 diabetes mellitus who underwent comprehensive neuropathy screening at the University of Debrecen between 2017 and 2021. The diagnosis of DSPN was made in accordance with international criteria, incorporating symptom scores, and electrophysiological measurements. Multivariate logistic regression was applied in order to identify independent predictors. Results: The diagnosis of DSPN was made in 444 individuals (71.5%), of whom 58.2% were female. Despite similar glycemic control (HbA1c: 7.81% in men vs. 7.65% in women, p = 0.297), men had significantly more frequent occurrences of previous myocardial infarction (11.8% vs. 5.0%, p = 0.008), peripheral vascular disease (19.9% vs. 12.7%, p = 0.041) and atherosclerosis (31.7% vs. 22.0%, p = 0.021). Multivariate analysis showed that female gender was independently associated with a lower incidence of DSPN (odds ratio [OR] = 0.592, 95% confidence interval [CI]: 0.369?0.950, p = 0.030), while diabetic retinopathy was a significant predictor (OR = 2.728, 95% CI: 1.300?5.725, p = 0.008). Electrophysiological testing revealed lower nerve conduction amplitudes in females for selected nerves. Conclusions: Our findings highlight sex-specific differences in neuropathy risk and support the implementation of individualized screening strategies in diabetic populations with region-specific risk factors.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
diabetic sensorimotor polyneuropathy
cardiovascular risk factors
sex differences
type 2 diabetes mellitus
Megjelenés:Journal of Clinical Medicine. - 14 : 16 (2025), p. 1-16. -
További szerzők:Pető Attila (1990-) (általános orvos) Tóth László (1997-) (orvos) Lőrincz Hajnalka (1986-) (biológus) Molnár Ágnes (1978-) (egészségpolitikus) Lukács Miklós (1994-) Menyhárt Adrienn Kempler Péter (1954-) (belgyógyász, diabetológus) Paragh György (1953-) (belgyógyász) Harangi Mariann (1974-) (belgyógyász, endokrinológus) Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
Pályázati támogatás:EFOP-3.6.2-16-2017-00009
EFOP
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10.

001-es BibID:BIBFORM130420
035-os BibID:(scopus)105006720594 (wos)001496780300001
Első szerző:Tar Ildikó (fogszakorvos)
Cím:Effects of Comorbid Disease Improvement on Oral Lichen Planus (OLP) and Oral Leukoplakia (OL) Lesions : a Retrospective Longitudinal Study / Tar Ildikó, Krisztina Szarka, Martos Renáta, Kiss Csongor, Márton Ildikó
Dátum:2025
ISSN:2077-0383
Megjegyzések:Background: Previous attempts to treat oral potentially malignant disorders OPMDs) effectively have failed. Longitudinal studies investigating the effects of comorbid diseases improvement on OPMDs are not yet available. Therefore, the current study examined the effects of comorbid disease improvement on OPMDs healing, both in oral lichen planus (OLP) and oral leukoplakia (OL) patients. Methods: The data from 197 consecutive patients (144 females and 53 males, age ? SD: 55.19 ? 12.37 years, with ages ranging from 23 to 91 years), with oral lesions considered OLP and OL, were processed and evaluated. The frequency of comorbid diseases and the presence of HPV (here, subtypes were not evaluated) in the lesions in OLP and OL patient groups were evaluated and compared to the results of controls (n = 139). Risk models for OLP and OL lesions were established. High-risk models for erosive?atrophic OLP and non-homogeneous OLP were also described. The influence of comorbid disease improvement was also evaluated. Lesions were scored at the first and last visit (full recovery = 0, improvement = 1, and no improvement = 2). Results: One hundred and ninety-seven patients (144 OLP + 53 OL) were followed up for an average of 47.66 months (min?max: 1?203 months, SD: 54.19). Based on the established models, HPV infection, iron deficiency, diabetes, and thyroid function disorders seem to act as risk factors for OLP and may also affect OL formation. The improvement in comorbid diseases can cause significant improvement in OLP and OL lesions. Conclusions: By meticulous follow-up of comorbid diseases, improvement in OLP and OL lesions can be achieved.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
oral lichen planus
oral leukoplakia
HPV
comorbid disease
prevention of cancer formation
Megjelenés:Journal of Clinical Medicine. - 14 : 10 (2025), p. 1-14. -
További szerzők:Szarka Krisztina (1971-) (molekuláris biológus, mikrobiológus) Martos Renáta (1975-) (fogszakorvos) Kiss Csongor (1956-) (hematológus, onkológus) Márton Ildikó (1954-) (fogszakorvos)
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11.

001-es BibID:BIBFORM131024
035-os BibID:(WoS)001526096800001 (Scopus)105010302930
Első szerző:Ulambayar, Battamir (orvos)
Cím:Artificial sweeteners and cardiovascular risk in Hungary : beyond traditional risk factors / Battamir Ulambayar, Attila Csaba Nagy
Dátum:2025
ISSN:2077-0383
Megjegyzések:Abstract Background/Objectives: Cardiovascular disease (CVD) remains a leading cause of mortality in Hungary, with rising obesity and diabetes rates exacerbating the burden. Artificial sweeteners, promoted as healthier alternatives to sugar, have been linked to CVD risk in other populations, but evidence in Hungary is limited. This study aims to investigate the association between artificial sweetener use and CVD prevalence in a Hungarian population, independent of traditional risk factors, using data from the 2019 European Health Interview Survey (EHIS). Methods: This cross-sectional study analyzed EHIS data (n = 5603), categorizing participants by self-reported CVD diagnoses (hypertension, coronary artery disease, myocardial infarction, or stroke). Variables included artificial sweetener use, age, sex, education, income, smoking, alcohol consumption, physical activity, diabetes, and body mass index (BMI). Chi-square tests and multivariate logistic regression, adjusted for sampling weights, were employed to assess associations. Results: Of 5603 participants, 38.7% had CVD and 16.4% used artificial sweeteners. Older age, female sex, lower education, long-term smoking cessation, obesity, diabetes, and physical inactivity increased CVD risk, while moderate alcohol consumption and sports were protective. Artificial sweetener use was significantly associated with higher CVD prevalence (OR: 1.21, 95% CI: 1.01?1.46, p = 0.01), independent of other risk factors. Conclusions: Artificial sweetener use is associated with increased CVD risk in Hungary, suggesting a need for further research and public health strategies to address this potential risk.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
cardiovascular disease
risk factors
artificial sweetener
European Health Interview Survey
Hungary
Megjelenés:Journal of Clinical Medicine. - 14 : 13 (2025), p. 1-11. -
További szerzők:Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

12.

001-es BibID:BIBFORM122130
035-os BibID:(Scopus)85197121133 (WoS)001255992400001
Első szerző:Ulambayar, Battamir (orvos)
Cím:Evaluation of cardiovascular disease risk in patients with type 2 Diabetes Mellitus using clinical laboratory markers / Battamir Ulambayar, Amr Sayed Ghanem, Nguyen Minh Chau, Eszter Vargáné Faludi, Marianna Móré, Attila Csaba Nagy
Dátum:2024
ISSN:2077-0383
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal of Clinical Medicine. - 13 (2024), p. 1-14. -
További szerzők:Ghanem, Amr Sayed (1991-) (orvos, fogorvos) Nguyen, Minh Chau Faludi Eszter Móré Marianna (1959-) (társadalomkutató) Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
Internet cím:DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
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