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001-es BibID:BIBFORM091171
035-os BibID:(WoS)000622892400001 (Scopus)85100108778
Első szerző:Cavalier, Etienne
Cím:Analytical Performance Specifications for 25-Hydroxyvitamin D Examinations / Cavalier Etienne, Fraser Callum G., Bhattoa Harjit P., Heijboer Annemieke C., Makris Konstantinos, Ulmer Candice Z., Vesper Hubert W., Vasikaran Samuel, Lukas Pierre, Delanaye Pierre, Carobene Anna, IFCC-IOF Committee for Bone Metabolism
Dátum:2021
ISSN:2072-6643
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Nutrients. - 13 : 2 (2021), p. 1-13. -
További szerzők:Fraser, Callum G. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Heijboer, Annemieke C. Makris, Konstantinos Ulmer, Candice Z. Vesper, Hubert W. Vasikaran, Samuel D. Lukas, Pierre Delanaye, Pierre Carobene, Anna IFCC-IOF Joint Committee for Bone Metabolism
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001-es BibID:BIBFORM084709
035-os BibID:(WoS)000531831300108 (Scopus)85083006648
Első szerző:Grant, William B.
Cím:Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths / Grant William B., Lahore Henry, McDonnell Sharon L., Baggerly Carole A., French Christine B., Aliano Jennifer L., Bhattoa Harjit P.
Dátum:2020
ISSN:2072-6643
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
COVID-19
SARS-CoV-2
Megjelenés:Nutrients. - 12 : 4 (2020), p. 1-19. -
További szerzők:Lahore, Henry McDonnell, Sharon L. Baggerly, Carole A. French, Christine B. Aliano, Jennifer L. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos)
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3.

001-es BibID:BIBFORM081577
035-os BibID:(WoS)000487964600213 (Scopus)85071735858 (PMID)31484329
Első szerző:Grant, William B.
Cím:Variations in 25-Hydroxyvitamin D in Countries from the Middle East and Europe : the Roles of UVB Exposure and Diet / William B. Grant, Hana M. A. Fakhoury, Spyridon N. Karras, Fatme Al Anouti, Harjit P. Bhattoa
Dátum:2019
ISSN:2072-6643
Megjegyzések:Serum 25-hydroxyvitamin D (25(OH)D) has been largely associated with latitude and sunshine exposure across several regions. According to previous results, 25(OH)D concentrations are, on average, relatively low in countries with abundant sunshine, including those of the Middle East and North Africa region, as well as lower-latitude Europe. The standard explanation for this phenomenon is that people wear concealing clothing because of cultural and religious practices and that high temperatures in summer limit direct sun exposure. However, the role of diet in the development of profound hypovitaminosis D has not been adequately explored in those countries. To examine how diet affects vitamin D status in the Middle Eastern and European countries, a search was conducted for papers from that region reporting 25(OH)D concentrations. Papers were sought that reported summertime and wintertime 25(OH)D concentrations for healthy nonpregnant adults representative of the entire population. Data from 15 Middle Eastern and European countries were found through this search. Data for postmenopausal women from 19 European countries were also obtained. Dietary supply data for animal products containing vitamin D (animal fat, eggs, ocean fish, animal meat, and milk) were obtained from the Food and Agriculture Organization of the United Nations. Latitude and a solar UVB dose index also were obtained for each country. For the 15-country study, energy from dietary factors was highly correlated with latitude, making it difficult to separate the effects of UVB exposure and dietary factors. However, for the 19-country study, dietary factors were only weakly correlated with latitude. In that study, ocean fish was the most important single dietary factor affecting serum 25(OH)D concentration for postmenopausal women in various European countries, but animal fat and meat also contributed. Because this is an ecological study, further research is encouraged to evaluate and extend the findings.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
25-hydroxyvitamin D
Europe
Middle East
animal fat
diet
eggs
latitude
ocean fish
solar UVB
vitamin D deficiency
Megjelenés:Nutrients. - 11 : 9 (2019), p. 1-16. -
További szerzők:Fakhoury, Hana M. A. Karras, Spyridon Al Anouti, Fatme Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos)
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4.

001-es BibID:BIBFORM134193
035-os BibID:(scopus)105024456285 (wos)001636258300001
Első szerző:Rácz Szilvia (molekulársi biológus)
Cím:Exploring Vitamin D Trends Through Big Data Analysis / Szilvia Racz, Miklos Emri, Ervin Berenyi, Laszlo Horvath, Bela E. Toth, Sandor Barath, Edit Kalina, Luca Jozsa, Amrit Pal Bhattoa-Buzas, William B. Grant, Harjit Pal Bhattoa
Dátum:2025
ISSN:2072-6643
Megjegyzések:Background/Objectives: Big data analysis has revolutionized medical research, making it possible to analyze vast amounts of data and gain valuable insights that were previously impossible to obtain. Our knowledge of the characteristics of vitamin D sufficiency is primarily based on data from a limited number of observations, generally spanning a few years at most. Methods: Here at the Medical Faculty of the University of Debrecen, the big data approach has allowed us to analyze trends in vitamin D status using nearly 60,000 25-hydroxyvitamin D (25(OH)D) concentration results from 2000 onwards. Results: Apart from analyzing the well-known phenomenon of seasonality in 25(OH)D concentration, we observed a trend in test requests, which increased from a few hundred in 2000 to almost 10,000 in 2020. Of particular interest is the change in the gender gap in test requests. In previous years, test requests were primarily from women, but by the end of the analysis period, a significant number of requests were from men as well. Since the data set includes all age groups, we analyzed 25(OH)D concentration for incremental age sets of five years, from a few months to 100 years old. The prevalence of vitamin D insufficiency (<75 nmol/L) was clearly demarcated among various years of observation, age groups, sexes, and seasons. Our data was particularly valuable for analyzing the effect of the methodology used for 25(OH)D determination. Three different methodologies were used during the study period, and clear, statistically significant bias was observed. Conclusions: Our results clearly demonstrate the effect of the methodology used to determine 25(OH)D concentrations on vitamin D status, explicitly highlighting the urgent need to standardize the various platforms used to measure this important analyte and its consequences for public health.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
25-hydroxyvitamin D
big data
methodology
seasonal variations
age
gender
vitamin D
Megjelenés:Nutrients. - 17 (2025), p. 1-16. -
További szerzők:Emri Miklós (1962-) (fizikus) Berényi Ervin (1964-) (radiológus) Horváth László (1973-) (gyógyszerész) Tóth E. Béla (1960-) (orvos) Baráth Sándor (1977-) (biológus) Kalina Edit (1971-) (laboratóriumi analitikus) Józsa Luca Bhattoa-Buzas, Amrit Pal Grant, William B. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos)
Pályázati támogatás:TKP2021-NKTA-34
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