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001-es BibID:	BIBFORM122687
035-os BibID:	(Scopus)85193485869 (WOS)001226448800001
Első szerző:	Abd Elaziz, Mohamed Adel
Cím:	The use of urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin for diagnosis of hepato-renal syndrome in advanced cirrhotic patients / Mohamed Adel Abd Elaziz, Asmaa Mustafa Gouda Elewa, Dina Zaki Mohamed Zaki Abdel Hamid, Nohier Essam Soliman Ahmed Hassan, Éva Csongrádi, Emad Hamdy Hamouda Mohammed, Mohammed Abdel Gawad
Dátum:	2024
ISSN:	0886-022X
Megjegyzések:	Background: Chronic liver disease is a common and important clinical problem.Hepatorenal syndrome (HRS) is a life threatening complication. Serum creatinine (Cr) remains the only conventional indicator of renal function. However, the interpretation of serum Cr level can be confounded by malnutrition and reduced muscle mass often observed in patients with severe liver disease. Here, we present a cross-sectional study to explore the sensitivity and specificity of other markers as urinary KIM-1 and NGAL for cases of HRS. Methods: Cross-sectional study was conducted on 88 patients who were admitted to Alexandria main university hospital. Enrolled patients were divided in two groups; group 1: patients with advanced liver cirrhosis (child B and C) who have normal kidney functions while group 2: patients who developed HRS. Stata? version 14.2 software package was used for analysis. Results: Group 1 included 18 males and 26 females compared to 25 males and 19 females in group 2 (p = 0.135). Only the urinary KIM-1 showed a statistically significant difference between both groups in the multivariate logistic regression analysis adjusted for gender, serum bilirubin, serum albumin, INR, serum K, AST and ALT levels. Conclusion: In conclusion, our study aligns with prior research, as seen in the consistent findings regarding Urinary NGAL elevation in cirrhotic patients with AKI. Urinary KIM-1, independent of Urinary NGAL, may have a role in precisely distinguishing between advanced liver cirrhosis and HRS and merits further exploration.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Hepatorenal syndrome liver cirrhosis neutrophil gelatinase-associated lipocalin serum creatinine urinary kidney injury molecule-1
Megjelenés:	Renal Failure. - 46 : 1 (2024), p. 1-5. -
További szerzők:	Asmaa Mustafa Gouda Elewa Dina Zaki Mohamed Zaki Abdel Hamid Nohier Essam Soliman Ahmed Hassan Csongrádi Éva (1969-) (szakorvos) Emad Hamdy Hamouda Mohammed Mohammed Abdel Gawad
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001-es BibID:	BIBFORM113512
035-os BibID:	(scopus)85150972590 (wos)000956853000001
Első szerző:	Fayed, Ahmed
Cím:	Is the combination of linagliptin and allopurinol better prophylaxis against post-contrast acute kidney injury? A multicenter prospective randomized controlled study / Ahmed Fayed, Ahmed A. Hammad, Dina O. Abdulazim, Hany Hammad, Mohamed Amin, Samir Elhadidy, Mona M. Salem, Ibrahim M. Abd ElAzim, Lajos Zsom, Éva Csongradi, Karim M. Soliman, Usama A. Sharaf El Din
Dátum:	2023
ISSN:	0886-022X
Megjegyzések:	Background Patients with diabetic kidney disease (DKD) are at increased risk to develop post-contrast acute kidney injury (AKI). Diabetic patients under dipeptidyl peptidase 4 inhibitors (DPP4Is) experience a lower propensity to develop AKI. We speculated that linagliptin as a single agent or in combination with allopurinol may reduce the incidence of post-contrast AKI in stage 3-5 chronic kidney disease (CKD) patients with underlying DKD. Methods Out of 951 DKD patients eligible for this study, 800 accepted to sign informed consent. They were randomly allocated to 4 equal groups that received their prophylaxis for 2 days before and after radiocontrast. The first control group received N-acetyl cysteine and saline, the 2(nd) received allopurinol, the 3(rd) group received linagliptin, and the 4(th) received both allopurinol and linagliptin. Post-procedure follow-up for kidney functions was conducted for 2 weeks in all patients. Results 20, 19, 14, and 8 patients developed post-contrast AKI in groups 1 through 4, respectively. Neither linagliptin nor allopurinol was superior to N-acetyl cysteine and saline alone. However, the combination of the two agents provided statistically significant renal protection: post-contrast AKI in group 4 was significantly lower than in groups 1 and 2 (p < 0.02 and <0.03, respectively). None of the post-contrast AKI cases required dialysis. Conclusion Linagliptin and allopurinol in combination may offer protection against post-contrast AKI in DKD exposed to radiocontrast. Further studies are needed to support this view.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Renal Failure. - 45 : 1 (2023), p. p. 1-7. -
További szerzők:	Hammad, Ahmed A. Abdulazim, Dina O. Hammad, Hany Amin, Mohamed Elhadidy, Samir Salem, Mona M. ElAzim, Ibrahim M. Abd Zsom Lajos (1968-) (belgyógyász, nefrológus) Csongrádi Éva (1969-) (szakorvos) Soliman, Karim M. Sharaf El Din, Usama A.
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001-es BibID:	BIBFORM061591
Első szerző:	Fülöp Tibor (kardiológus)
Cím:	Recalcitrant hypoglycemia resolved with 2.5% dextrose containing replacement fluid during hemodiafiltration / Fülöp Tibor, Iboaya, Benahili U., Avusula, Ramachandram, Csongrádi Éva, Juncos, Luis A.
Dátum:	2013
ISSN:	0886-022X
Megjegyzések:	A 52-year-old African American male was admitted with acute kidney injury (AKI) four days afterrenal cryotherapy. He was started on continuous veno-venous hemodiafiltration (CVVHDF)immediately but his subsequent course was complicated by recurrent hypoglycemia, poorlyresponding to conventional therapy. To address the recalcitrant hypoglycemia, we changed thereplacement fluid to 5% dextrose in water with 150 mEq/L of sodium bicarbonate, Y-connectedwith 0.9% sodium chloride at a global rate of 2000 mL/hr, with resolution of refractoryhypoglycemia. A modified CVVHDF employing hyperglycemic solution can be a valuableaddition in treatment of AKI complicated by severe refractory hypoglycemia
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Acute kidney injury continuous renal replacement therapy hemodiafiltration hypoglycemia glipizide sulfonylurea
Megjelenés:	Renal Failure. - 35 : 7 (2013), p. 1035-7. -
További szerzők:	Iboaya, Benahili U. (orvos) Avusula, Ramachandram (orvos) Csongrádi Éva (1969-) (szakorvos) Juncos Luis A. (orvos)
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001-es BibID:	BIBFORM061608
Első szerző:	Fülöp Tibor (kardiológus)
Cím:	The safety and efficacy of bedside removal of tunneled hemodialysis catheters by nephrology trainees / Fülöp Tibor, Tapolyai Mihály, Qureshi, Naseem A., Beemidi, Vikram R., Gharaibeh, Kamel A., Hamrahian, S. Mehrdad, Szarvas, Tibor, Kovesdy, Csaba P., Csongrádi, Éva
Dátum:	2013
ISSN:	0886-022X
Megjegyzések:	BACKGROUND:Some nephrologists remove tunneled hemodialysis catheters (TDC) at the bedside, but this practice has never been formally studied. Our hypothesis was that bedside removal of TDC is a safe and effective procedure affording prompt removal, including in cases of suspected infection.METHODS:We reviewed our consecutive 3-year experience (2007-2009) with bedside TDC removal at the University of Mississippi Renal Fellowship Program. Data were collected on multiple patients and procedure-related variables, success and complication rates. Association between clinical characteristics and biomarkers of inflammation and myocardial damage was examined using correlation coefficients.RESULTS:Of 55 inpatient TDC removals (90.9% from internal jugular location), 50 (90.9%) were completed without hands-on assistance from faculty. Indications at the time of removal included bacteremia, fever or clinical sepsis with hemodynamic instability or respiratory failure. All procedures were successful, with no cuff retention noted; one patient experienced prolonged bleeding which was controlled with local pressure. Peak C-reactive protein (available in 63.6% of cohort) was 12.9???8.4?mg/dL (reference range: <0.49) and median troponin-I (34% available) was 0.534?ng/mL (IQR 0.03-0.9) (reference range: <0.034) and they did not correlate with each other. Abnormal troponin-I was associated with proven bacteremia (p?<?0.05) but not with systolic and diastolic BP or clinical sepsis.CONCLUSION:Our results suggest that bedside removal of TDC remains a safe and effective procedure regardless of site or indications. Accordingly, TDC removal should be an integral part of competent Nephrology training.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Renal Failure. - 35 : 9 (2013), p. 1264-1268, -
További szerzők:	Tapolyai Mihály (1968-) (nefrológus) Qureshi, Naseem A. Beemidi, Vikram R. (orvos) Gharaibeh, Kamel A. (orvos) Hamrahian, S. Mehrdad (orvos) Szarvas Tibor (matematikus informatikus) Kovesdy Csaba P. (orvos) Csongrádi Éva (1969-) (szakorvos)
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