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1.

001-es BibID:BIBFORM127468
035-os BibID:(WoS)001322841800001 (Scopus)85206834195
Első szerző:Al hamza Hasoon, Buthenia Abd
Cím:Tangerine fruit peel extract mediated biogenic synthesized silver nanoparticles and their potential antimicrobial, antioxidant, and cytotoxic assessments / Buthenia Abd Al hamza Hasoon, Bassam Shaker Mahmood, Erieg Abdulwahab Mohamed, Majid Sakhi Jabir, Kareem Hussein Jawad, Nehia Neama Hussein, Ghassan Mohammad Sulaiman, Yaser Hassan Dewir, Nóra Mendler-Drienyovszki
Dátum:2024
ISSN:2191-9542 2191-9550
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Green Processing and Synthesis. - 13 : 1 (2024), p. 1-17. -
További szerzők:Mahmood, Bassam Shaker Mohamed, Erieg Abdulwahab Jabir, Majid Sakhi Jawad, Kareem Hussein Hussein, Nehia Neama Sulaiman, Ghassan Mohammad Dewir, Yaser Hassan Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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2.

001-es BibID:BIBFORM122745
035-os BibID:(Scopus)85199892552 (WoS)001278445300001
Első szerző:Bansal, Mahima
Cím:An Efficient In Vitro Shoot Organogenesis and Comparative GC-MS Metabolite Profiling of Gaillardia pulchella Foug / Bansal, Mahima; Mujib, A.; Bansal, Yashika; Dewir, Yaser Hassan; Mendler-Drienyovszki, Nóra
Dátum:2024
ISSN:2311-7524
Megjegyzések:Gaillardia pulchella Foug. is a widely studied plant because of its high pharmacological and ornamental value. The leaves of G. pulchella were used for inducing callus and subsequent plant regeneration as it is the primary source of phytocompounds. The purpose of the present investigation was to formulate an in vitro propagation method for Gaillardia by using leaf explants in MS (Murashige and Skoog) medium. The best callus induction was observed on high (2.0 mg/L) ?-naphthalene acetic acid (NAA) and a low (0.5 mg/L) 6-benzylaminopurine (BAP) with callus induction frequency of 91.66%. The leaf callus also demonstrated high caulogenesis ability (95.83%), with an average 5.2 shoots/callus mass at 0.5 mg/L BAP and 2.0 mg/L NAA. Indole Acetic acid (IAA) at 1.0 mg/L had the maximum rooting percentage (79.17%) with 12.4 roots per shoot. Rooted plantlets were later transferred to greenhouse conditions, showing a survivability rate of 75?80%. The physiological parameters, i.e., phenolic compounds and the flavonoids' level, in the DPPH assay were higher in leaves obtained in vitro compared to callus formed from leaves and field-obtained (mother) leaves. Gas chromatography?mass spectrometry (GC?MS) analysis of methanol extracts of leaves (in vivo and in vitro) and leaf callus presented a wide array of compounds. In callus extract, some 34 phytocompounds were identified. Some of them were 3-hydroxy-2,3-dihydromaltol (25.39%), isoamyl acetate (11.63%), palmitic acid (11.55%), 4-methyloxazole (7.54%), and 5-methoxypyrrolidin-2-one (7.49%). Leaves derived in vivo and in vitro had 45 and 28 phytocompounds, respectively, belonging to different classes like lignans, phenols, terpenoids, alkaloids and fatty acids, etc. Those findings demonstrated that the leaf derived callus and the leaves are the potential stable source of several compounds with medicinal importance. The developed protocol may provide an alternative source of compounds without affecting wild flora.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
indirect organogenesis
biochemical
antioxidant
phytochemical fingerprinting
chromatography
Megjelenés:Horticulturae. - 10 : 7 (2024), p. 1-17. -
További szerzők:Mujib, Abdul Bansal, Yashika Dewir, Yaser Hassan Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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3.

001-es BibID:BIBFORM123459
035-os BibID:(Scopus)85203308788 (WoS)001330273700001
Első szerző:Bansal, Yashika
Cím:Integrated GC-MS and UPLC-ESI-QTOF-MS based untargeted metabolomics analysis of in vitro raised tissues of Digitalis purpurea L / Bansal, Yashika; Mujib, A.; Mamgain, Jyoti; Syeed, Rukaya; Mohsin, Mohammad; Nafees, Afeefa; Dewir, Yaser Hassan; Mendler-Drienyovszki, Nóra
Dátum:2024
ISSN:1664-462X
Megjegyzések:Digitalis purpurea L. is one of the important plant species of Nilgiris, Kashmir and Darjeeling regions of India, belonging to the family Plantaginaceae, with well known pharmacological applications. In the present investigation, an in vitro culture technique of indirect shoot organogenesis of D. purpurea is being explored; the biochemical attributes, the antioxidant activities and the metabolomic analyses were made by utilizing untargeted Gas Chromatography-Mass Spectrometry (GC-MS) and Ultra Performance Liquid Chromatography coupled with electronspray ionization/quadrupole-time-of flight-mass spectrometry (UPLC-ESI-QTOF-MS) approaches. Initially, the leaf explants were used for callus induction and proliferation and maximum callusing frequency (94.44%) and fresh biomass (4.9 g) were obtained on MS, fortified with 8.8 ?MBAP(6-benzylaminopurine) +0.9?M2,4-D(2,4-dichlorophenoxyacetic acid), subsequently shoot formation (indirect organogenesis) was noted on the same MS medium with a shoot induction frequency of 83.33%. Later on, the biochemical and antioxidant potential of in vivo-, in vitro grown leaf and leaf derived callus were assessed. Significantly higher total phenol, flavonoid, DPPH (2,2-diphenyl-1-picrylhydrazyl), POD (peroxidase) and SOD (superoxide dismutase) activities were noticed in in vitro grown callus and leaf tissues compared with field grown leaf. The GC-MS analysis of each methanolic extract (in vivo-, in vitro derived leaf and leaf derived callus) displayed the presence of more than 75 bioactive compounds viz loliolide, stigmasterin, alpha-tocopherol, squalene, palmitic acid, linoleic acid, beta-amyrin, campesterol etc. possessing immense therapeutic importance. The UPLC-MS based metabolite fingerprinting of each methanolic extracts were conducted in both positive and negative ionization mode. The obtained results revealed variation in phytochemical composition in field- and laboratory grown tissues, indicating the impact of in vitro culture conditions on plant tissues. The detected phytocompounds belongs to various classes such as flavonoids, steroids, terpenoids, carbohydrates, tannins, lignans etc. The medicinally important metabolites identified were 20, 22-dihydrodigoxigenin, digoxigenin monodigitoxoside, apigenin, luteolin, kaempferide, rosmarinic acid, nepitrin and others. The results of the present study suggest that in vitro culture of D. purpurea could successfully be utilized for the novel drug discovery byproducing such important phytocompounds of commercial interest in shorter duration without harming the plants' natural population.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
metabolomics
indirect organogenesis
biochemical
SOD
POD
GC-MS
UPLC-ESI QTOF-MS
cardenolides
Megjelenés:Frontiers in Plant Science. - 15 (2024), p. 1-29. -
További szerzők:Mujib, Abdul Mamgain, Jyoti Syeed, Rukaya Mohsin, Mohammad Nafees, Afeefa Dewir, Yaser Hassan Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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4.

001-es BibID:BIBFORM123296
035-os BibID:(Scopus)85202680412 (WoS)001307220500001
Első szerző:Fatima, Tooba
Cím:Indirect Organogenesis of Calendula officinalis L. and Comparative Phytochemical Studies of Field-Grown and In Vitro-Regenerated Tissues / Fatima, Tooba; Mujib, A.; Bansal, Yashika; Dewir, Yaser Hassan; Mendler-Drienyovszki, Nóra
Dátum:2024
ISSN:2073-4395
Megjegyzések:Calendula officinalis L. is an important medicinal and ornamental plant possessing multiple bioactive compounds. The in vitro plant regeneration method has recently replaced traditional field cultivation practices of calendula due to its fascinating phytochemical profile. In this study, callus formation and indirect organogenesis were described to establish an effective in vitro propagation strategy in C. officinalis. Using a gas chromatography-mass spectrometry (GC-MS) approach, the phytochemical content of tissues developed in vitro and field-grown was studied, and the biochemical contents were quantified and compared in various tissues. The incidence of callus formation from leaf explants was highest (94.44%) on MS medium fortified with 1.0 mg/L BAP and 1.0 mg/L NAA, which later became organogenic. On MS, 1.0 mg/L BAP and 1.0 mg/L NAA showed the highest indirect shoot proliferation (88.88%) efficiency. After being sub-cultured, the regenerated shootlets were cultured onto rooting medium containing different IAA/IBA concentrations; the best rooting percentage (94.44%) was achieved with 1.0 mg/L IBA. The biochemical parameters, like total phenolic content, flavonoid content, and DPPH scavenging activity, were measured. When compared to callus and field-grown developed leaf (donor) samples, all the biochemical characteristics of in vitro-produced leaf were noted to be higher. The methanolic extracts of leaf-callus and field-grown and in vitro-developed leaf tissues were subject to GC-MS-based phytocompound investigation. More than 45 therapeutically significant bioactive chemicals, like n-hexadecanoic acid, vitamin E, stigmasterol, and squalene were found in these samples. These results showed that the callus that is formed from in vitro leaf is a reliable and powerful source of several bioactive compounds with a wide range of medicinal uses. The successful stimulation of callus development, indirect organogenesis, biochemical analysis, and GC-MS confirmation of the presence of significant phytocompounds are all described in this study. This work provides a different avenue for ongoing and sustained synthesis of chemicals without endangering the surrounding ecosystem or native vegetation.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
pot marigold
indirect organogenesis
biochemical
GC-MS
antioxidant
phytochemical profiling
Megjelenés:Agronomy-Basel. - 14 : 8 (2024), p. 1-17. -
További szerzők:Mujib, Abdul Bansal, Yashika Dewir, Yaser Hassan Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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5.

001-es BibID:BIBFORM124150
035-os BibID:(Scopus)85205237039 (WoS)001326289000001
Első szerző:Gangaram, Serisha
Cím:Biosynthesis of Silver Nanoparticles Using Barleria albostellata C.B. Clarke Leaves and Stems: Antibacterial and Cytotoxic Activity / Gangaram, Serisha; Naidoo, Yougasphree; Dewir, Yaser Hassan; Singh, Moganavelli; Lin, Johnson; Nicole Daniels, Aliscia; Mendler-Drienyovszki, Nóra
Dátum:2024
ISSN:2076-3417
Megjegyzések:Silver nanoparticles (AgNPs) have increasingly gained attention owing to their distinctive physicochemical and biological properties. The objective of the investigation was to biologically synthesize AgNPs using plant extracts from Barleria albostellata. The synthesized AgNPs, obtained from B. albostellata (leaves and stems), were characterized through various techniques including UV-visible spectroscopy, scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), energy-dispersive X-ray analysis, Fourier transform infrared (FTIR) spectral analysis, and nanoparticle tracking analysis (NTA). The antibacterial efficacy of the synthesized AgNPs was evaluated utilizing the disk diffusion method. The cytotoxicity effects of the synthesized AgNPs were determined using the MTT assay (3-[(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide]) in cervical cancer (HeLa), embryonic kidney (HEK293), and breast adenocarcinoma (MCF-7) cell lines. The results indicate that B. albostellata extracts could serve as eco-friendly biofactories for the synthesis of AgNPs. UV-vis spectroscopy of the leaf and stem extracts revealed absorption peaks within the range of 400?450 nm, thereby confirming the synthesis of AgNPs. Elemental Ag was highest in the methanol leaf extracts (16.87 ? 0.89%) and lowest in the powdered stem extracts (7.13 ? 1.44%). Synthesized AgNPs were predominantly spherical in shape. HRTEM revealed that synthesized AgNPs from the methanolic stem extracts (34.32 ? 16.99 nm) were larger in size, while those from the powdered stem extracts were smaller (16.57 ? 5.55 nm). AgNPs synthesized from both the leaf and stem extracts exhibited zeta potential values between ?8.8 and ?32.1 mV, with hydrodynamics diameters ranging from 34.3 to 111.3 nm. FTIR spectroscopy confirmed the presence of various functional groups on the AgNPs. AgNPs synthesized from the leaf and stem extracts displayed significant antibacterial activity and were sensitive to Gram-negative and Gram-positive bacteria. AgNPs exhibited significant antibacterial activity (diameter of the zone of inhibition) against Pseudomonas aeruginosa (21.67 ? 2.87 mm) in the leaf methanolic extract. Synthesized AgNPs exhibited selective in vitro cytotoxicity against HEK293, HeLa, and MCF-7 cell lines. The IC50 values of the AgNPs synthesized from the various extracts were all above 9 ?g/mL. Significant cytotoxic levels (IC50 16.11 and 27.23 ?g/mL) were observed for the MCF-7 cell line upon exposure to the methanolic leaf and stem AgNPs. This study recommends the use of medicinal plant extracts in producing economically effective AgNPs, due to their efficient capping. Overall, AgNPs synthesized from B. albostellata extracts comprised novel antibacterial and anticancer agents, and warrant further investigation. Bio-synthesized AgNPs show great potential in the area of nanotechnology and may be used as an affordable, eco-friendly alternative for the delivery of conventional therapeutics.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
antibacterial activity
biofactories
biosynthesis
cytotoxicity
elemental Ag+
Megjelenés:Applied Sciences-Basel. - 14 : 18 (2024), p. 1-30. -
További szerzők:Naidoo, Yougasphree Dewir, Yaser Hassan Singh, Moganavelli Lin, Johnson Daniels, Aliscia Nicole Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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6.

001-es BibID:BIBFORM116137
035-os BibID:(WoS)001114630200001 (Scopus)85178271139
Első szerző:Gangaram, Serisha
Cím:Antioxidant and Cytotoxic Activities of Leaf and Stem Extracts of Barleria albostellata C.B. Clarke / Gangaram, Serisha; Naidoo, Yougasphree; Dewir, Yaser Hassan; Singh, Moganavelli; Daniels, Aliscia Nicole; Magyar-Tábori, Katalin; Mendler-Drienyovszki, Nóra
Dátum:2023
ISSN:2311-7524
Megjegyzések:Barleria albostellata C.B. Clarke (Acanthaceae) is a plant native to South Africa and relatively few studies have been performed on it. Species in this genus are known for their ethnopharmacological and phyto-medicinal values. In this study, the total flavonoid and phenolic contents and the antioxidant and cytotoxic activities of hexane, chloroform, and methanol extracts were evaluated at five different concentrations (15, 30, 60, 120, and 240 mu g/mL). The antioxidant activity of the extracts of B. albostellata was assessed in vitro using the 2,2 '-diphenyl-1-picrylhydrazyl (DPPH) scavenging and ferric reducing antioxidant power (FRAP) assays, while the phenolic content was determined using a Folin-Ciocalteu assay. The extracts' cytotoxicity was established using a 3-[(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] (MTT) assay in human embryonic kidney (HEK293), cervical cancer (HeLa), and breast adenocarcinoma (MCF-7) cell lines. Methanolic leaf extracts had the highest total flavonoid content (42.39 +/- 1.14 mg GAE/g DW) compared to other solvents. Additionally, the total phenolic content was the greatest in the methanol leaf extract (6.05 +/- 0.09 GAE/g DW), followed by the methanol stem extracts (2.93 +/- 0.73 GAE/g DW). The methanolic leaf and stem extract concentrations needed for 50% inhibition (DPPH) were 16.95 mu g/mL and 14.27 mu g/mL, respectively, whereas for FRAP, the reducing powers of all extracts were considerably lower than the ascorbic acid standard. The IC50 values of extracts tested in the three cell lines were >63 mu g/mL. According to the findings of our study, the leaves and stems of B. albostellata are rich in several bioactive compounds that may be a possible source of natural antioxidants and may have the potential to treat certain diseases. The extraction of the bioactive compounds from the leaves and stems of B. albostellata using bioassay-guided fractionation and the assessment of their safety will be essential for further investigations into this species in the search of potential novel therapeutic drug leads. To the best of our knowledge, this is the first report of the cytotoxic activities of leaf and stem extracts of Barleria albostellata.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Horticulturae. - 9 : 11 (2023), p. 1-18. -
További szerzők:Naidoo, Yougasphree Dewir, Yaser Hassan Singh, Moganavelli Daniels, Aliscia Nicole Magyarné Tábori Katalin (1965-) (kertészmérnök) Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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7.

001-es BibID:BIBFORM127469
035-os BibID:(Scopus)85210449678 (WoS)001365592400001
Első szerző:Khan, Muhammad Waqar
Cím:A Novel Solid Media-Free In-Planta Soybean (Glycine max. (L) Merr.) Transformation Approach / Muhammad Waqar Khan, Aaqib Shaheen, Xuebin Zhang, Yaser Hassan Dewir, Nóra Mendler-Drienyovszki
Dátum:2024
ISSN:2075-1729
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Life. - 14 : 11 (2024), p. 1-12. -
További szerzők:Shaheen, Aaqib Zhang, Xuebin Dewir, Yaser Hassan Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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8.

001-es BibID:BIBFORM123917
035-os BibID:(Scopus)85204146962 (WoS)001311480700001
Első szerző:Murthy, Hosakatte Niranjana
Cím:Nutritional Value, Fatty Acid and Phytochemical Composition, and Antioxidant Properties of Mysore Fig (Ficus drupacea Thunb.) Fruits / Murthy, Hosakatte Niranjana; Yadav, Guggalada Govardhana; Joseph, Kadanthottu Sebastian; H. S., Sabha Khan; Magi, Snehalata M.; Dewir, Yaser Hassan; Mendler-Drienyovszki, Nóra
Dátum:2024
ISSN:2304-8158
Megjegyzések:Ficus drupacea is a fruit-bearing tree that is distributed in Southeast Asia and Australia. The objective of this research was to ascertain the following with regard to ripened fruits: (i) their nutritional value, (ii) their mineral status, (iii) the fatty acid composition of fruit and seed oil, (iv) their phytochemical makeup, and (v) their antioxidant properties. The ripened fruits contained 3.21%, 3.25%, 0.92%, 1.47%, and 2.20% carbohydrate, protein, fat, ash, and fiber, respectively. Fruits had an energy content of 30.18 kcal/100 g. In terms of mineral content, the fruit was rich in potassium, magnesium, calcium, and nitrogen, with values of 21.03, 13.24, 11.07, and 4.13 mg/g DW. Iron, zinc, manganese, and boron had values of 686.67, 124.33, 114.40, and 35.78 ?g/g DW, respectively. The contents of oxalate and phytate were 14.44 and 2.8 mg/g FW, respectively. The fruit and seed oil content were 0.67 and 8.07%, respectively, and the oil's physicochemical properties were comparable to those of fig fruit and seed oils. Omega-3 (?-linolenic acid), omega-6 (linoleic acid), and omega-9 (oleic acid) fatty acids were abundant in the oils. Fruit extracts in acetone, methanol, and water have greater concentrations of phenolics, flavonoids, and alkaloids. The 2,2-diphenyl-2-picrylhydrazyl, total antioxidant activity, and ferric reducing antioxidant power assays demonstrated increased antioxidant activities in close correlation with the higher concentrations of phenolics, flavonoids, and alkaloids. The results of this study demonstrate that the fruits of F. drupacea are a strong source of nutrients and phytochemicals, and they merit more investigation and thought for possible uses.
Tárgyszavak:Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
antioxidant activity
Ficus drupacea
minerals
mysore fig
nutrients
proximate analysis
Megjelenés:Foods. - 13 : 17 (2024), p. 1-16. -
További szerzők:Yadav, Guggalada Govardhana Joseph, Kadanthottu Sebastian Khan, Sabha H. S. Magi, Snehalata M. Dewir, Yaser Hassan Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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9.

001-es BibID:BIBFORM119529
035-os BibID:(Scopus)85188034084 (WoS)001222829500008
Első szerző:Naidoo, Danesha
Cím:Foliar Micromorphology and Histo-phytochemistry of Cucumber Trees (Kigelia africana (Lam.) Benth) / Naidoo, Danesha ; Naidoo, Yougasphree ; Dewir, Yaser H. ; Alshahrani, Thobayet ; Hassan, Wael M. ; Mendler-Drienyovszki, Nóra
Dátum:2024
ISSN:2357-0350
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Egyptian Journal of Botany. - 64 : 2 (2024), p. 1-13. -
További szerzők:Naidoo, Yougasphree Dewir, Yaser Hassan Alshahrani, Thobayet Hassan, Wael M. Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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10.

001-es BibID:BIBFORM129364
Első szerző:Omran, Hiba Jameel
Cím:Extraction, characterization, and biological activities of anthocyanin pigment from prunus domestica L. fruit peels / Omran, Hiba Jameel; Hussein, Amal Ali; Hasoon, Buthenia A.; Dewir, Yaser Hassan; Magyar-Tábori, Katalin; Mendler-Drienyovszki, Nóra
Dátum:2025
ISSN:2331-1932
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Cogent Food & Agriculture. - 11 : 1 (2025), p. 1-16. -
További szerzők:Hussein, Amal Ali Hasoon, Buthenia A. Dewir, Yaser Hassan Magyarné Tábori Katalin (1965-) (kertészmérnök) Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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