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001-es BibID:	BIBFORM015518
Első szerző:	Berta Eszter (belgyógyász)
Cím:	Evaluation of the thyroid function of healthy pregnant women by five different hormone assays / Berta E., Sámson L., Lenkey Á., Erdei A., Cseke B., Jenei K., Major T., Jakab A., Jenei Z., Paragh Gy., Nagy E., Bodor M.
Dátum:	2010
ISSN:	0031-7144
Megjegyzések:	A normal function of the thyroid gland during pregnancy is essential. Any change can affect both the pregnant woman and the fetus. Thyroid hormones play a crucial role in the brain development of the fetus, thus proper maternal free thyroid hormone levels are important especially during the first trimester. We compared the free thyroid hormone levels FT3 and FT4 in forty pregnant women with no thyroidal disease by five different assays available on the market. The blood samples were collected between the 8th and 22nd weeks of pregnancy. The correlation coefficient "r" between different assays was 0.908-0.975 for TSH, 0.676-0.892 for FT4 and 0.480-0.789 for FT3. These data show that the inter-assay results varied widely in the studied population. One reasonable explanation may be that during pregnancy the serum levels of the thyroid hormone binding proteins are altered and "free" hormone measurements by immunoassays are influenced by these alterations. Thus, the results may show higher or lower thyroid hormone values depending upon the assay used. Therefore, it is strongly suggested that every laboratory should establish its own pregnant reference ranges for the tests used for the evaluation of thyroid function, based on values of the population served.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Pharmazie 65 : 6 (2010), p. 436-439. -
További szerzők:	Sámson L. Lenkey Ágota (1944-) (biológus) Erdei Annamária (1976-) (belgyógyász) Cseke Béla (1974-) (belgyógyász, endokrinológus) Jenei Katalin Major Tamás (1963-) (szülész-nőgyógyász) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Jenei Zoltán (1968-) (belgyógyász) Paragh György (1953-) (belgyógyász) Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Bodor Miklós (1969-) (belgyógyász, endokrinológus)
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001-es BibID:	BIBFORM125832
Első szerző:	Csehely Szilvia (szülész-nőgyógyász szakorvos)
Cím:	Primary hyperparathyroidism recognised in pregnancy / Szilvia Csehely, Klaudia Balog, Roland Fedor, Mónika Andrási, Peter Damjanovich, Tamás Deli, Endre Nagy, Sándor Barna, Ferenc Győri, Miklós Bodor, Attila Jakab
Dátum:	2020
Megjegyzések:	Hyperparathyreodism is a rare condition, and has added risk if present in pregnancy. Management requires high expertise. Primary hyperparathyroidism diagnosed in pregnany is uncommon and is most often due to a solitary parathyroid adenoma. It is usually asymptomatic, since symptoms of hypercalcemia may be difficult to diagnosis, as they are frequently similar to those of pregnancy, such as nausea, fatigue and vomiting. Pregnant women with hyperparathyreodism has a significantly higher risk for obstetrical complications, but what is more important, the life of the fetus is in danger. The risk of early spontaneous abortion is elevated, which correlates with maternal serum calcium levels. The highest risk for fetal demise is at very high Ca-levels (above 12mg/dl), risk is up to 85% at 13 mg/dl Ca-levels. Early recognition and treatment are crucial to preventing long-term or lethal consequences. If is not recognised in time or untreated it can result in maternal preecclampsia, there might be cardiac arrythmia during labor, and preterm birth, IUGR, fetal demise is also more common. If the fetal parathyroid glands are fail to develop normally, permanent hypoparathyreodism might be present at the fetus, and postnatal hypocalcemic tetany might occur to the newborn. We present a case of primary hyperparathyroidism due to a parathyroid adenoma in a 28-year-old G1P0 pregnant women who was diagnosed by routine laboratory result at the 7th gestational week. Urgent parathyroidectomy was required. The successful management of the patient was possible with an intensive collaboration of obstetrician, endocrinologist, surgeon, and anaesthesiologist.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk primary hyperparathyroidism pregnancy
Megjelenés:	Gynecological and Reproductive Endocrinology & Metabolism (2020). - Supplement 1 (2020), p. 490. -
További szerzők:	Balog Klaudia (1988-) (sebész szakorvos) Fedor Roland (1975-) (sebész) Andrási Mónika Damjanovich Péter Gábor (1985-) (szülész-nőgyógyász) Deli Tamás (1979-) (szülész-nőgyógyász, endokrinológus szakorvos) Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Barna Sándor (1982-) (kutató orvos) Győri Ferenc Bodor Miklós (1969-) (belgyógyász, endokrinológus) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus)
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001-es BibID:	BIBFORM053793
Első szerző:	Molnár Zsuzsanna (szülész-nőgyógyász, labor szakorvosjelölt, urológus)
Cím:	Fertility of testicular cancer patients after anticancer treatment : experience of 11 years / Z. Molnár, E. Berta, M. Benyó, R. Póka, Z. Kassai, T. Flaskó, A. Jakab, M. Bodor
Dátum:	2014
ISSN:	0031-7144
Megjegyzések:	Testicular cancer affects men mostly in their reproductive age with a cure rate over 90%. Preserved fertilityis one of the main concerns of the survivors. To further elucidate the question of fertility after anticancertreatment for testicular cancer, we performed a survey among patients who underwent spermcryopreservationprocedure in our department. A structured questionnaire was designed to collect data on demography,anticancer treatment, histological type of cancer, family planning intentions and fertility prior to and aftertreatment. During a period of 11 years 86 men underwent semen cryopreservation before starting chemoorradiotherapy. Fifty-nine of them consented to participate in the study. The average length of follow upwas 4.6?3.8 years. In case of 11.9% of the patients their banked sperm was used, which led to live birthin 57% of the couples. The partners of 6 patients became pregnant after in vitro fertilization (IVF) resultingin 4 live births and 2 miscarriages. The spontaneous pregnancy rate was 22%. Spontaneous pregnancyoccurred in 13 partners resulting in 18 pregnancies followed by 12 live births, 2 artificial abortions and 4miscarriages. We could not prove any association between preserved fertility and anticancer treatment orthe histological type of the cancer. In conclusion, although spontaneous pregnancy rate is remarkably highafter anticancer treatment for testicular cancer, the risk of infertility after receiving gonadotoxic treatmentcannot be predicted. Cryopreservation is a safe and effective method to preserve fertility in these cases.As a result we strongly recommend discussing the advantages of semen cryopreservation with all patientsawaiting treatment for testicular cancer.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Pharmazie 69 : 6 (2014), p. 437-441. -
További szerzők:	Berta Eszter (1980-) (belgyógyász) Benyó Mátyás (1982-) (urológus) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Bazsáné Kassai Zsuzsa (1946-) (embriológus) Flaskó Tibor (1960-) (urológus) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Bodor Miklós (1969-) (belgyógyász, endokrinológus)
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