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001-es BibID:	BIBFORM121449
035-os BibID:	(Scopus)85190593422 (WOS)001203912900001
Első szerző:	Wéber András
Cím:	Global burden of bladder cancer mortality in 2020 and 2040 according to GLOBOCAN estimates / András Wéber, Jerome Vignat, Richa Shah, Eileen Morgan, Mathieu Laversanne, Péter Nagy, István Kenesse, Ariana Znaor
Dátum:	2024
ISSN:	1433-8726
Megjegyzések:	Introduction: In 2020, bladder cancer (BC) was the seventh most prevalent cancer in the world, with 5-year prevalence of more than 1.7 million cases. Due to the main risk factors-smoking and chemical exposures-associated with BC, it is considered a largely preventable and avoidable cancer. An overview of BC mortality can allow an insight not only into the prevalence of global risk factors, but also into the varying efficiency of healthcare systems worldwide. For this purpose, this study analyzes the national mortality estimates for 2020 and projected future trends up to 2040. Materials and methods: Age-standardized mortality rates per 100,000 person-years of BC for 185 countries by sex were obtained from the GLOBOCAN 2020 database, operated by the International Agency for Research on Cancer (IARC). Mortality rates were stratified according to sex and Human Development Index (HDI). BC deaths were projected up to 2040 on the basis of demographic changes, alongside different scenarios of annually increasing, stable or decreasing mortality rates from the baseline year of 2020. Results: In 2020, nearly three times more men died from BC than women, with more than 210,000 deaths in both sexes combined, worldwide. Regardless of gender, more than half of the total BC deaths were from countries with a very high HDI. According to our projections, while the number of deaths for men can only increase up to 54% (from 159 to around 163-245 thousand), for women it is projected to increase two- to three-fold (from 50 to around 119-176 thousand) by 2040. The burden of BC mortality in countries with a very high HDI versus high HDI appears to converge by 2040 for both sexes. Conclusion: Opposite mortality trends by gender highlight the urgent need for immediate interventions to expand anti-tobacco strategies, especially for women. The implementation of more strict occupational health and safety regulations could also prevent exposures associated with BC. Improving the ability to detect BC earlier and access to treatment can have a significant positive impact on reducing mortality rates, minimizing economic costs, and enhancing the quality of life for patients.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Bladder cancer Mortality Projection
Megjelenés:	World Journal of Urology. - 42 : 1 (2024), p. 1-10. -
További szerzők:	Vignat, Jerome Shah, Richa Morgan, Eileen Laversanne, Mathieu Nagy Péter (1976-) (vegyész) Kenessey István Znaor, Ariana
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM113488
035-os BibID:	(Scopus)85158910226 (WoS)001001381400001
Első szerző:	Wéber András
Cím:	Lung cancer mortality in the wake of the changing smoking epidemic: a descriptive study of the global burden in 2020 and 2040 / András Wéber, Eileen Morgan, Jerome Vignat, Mathieu Laversanne, Margherita Pizzato, Harriet Rumgay, Deependra Singh, Péter Nagy, István Kenessey, Isabelle Soerjomataram, Freddie Bray
Dátum:	2023
ISSN:	2044-6055
Megjegyzések:	Objectives - Lung cancer (LC) is the leading cause of cancer death in 2020, responsible for almost one in five (18.0%) deaths. This paper provides an overview of the descriptive epidemiology of LC based on national mortality estimates for 2020 from the International Agency for Research on Cancer (IARC), and in the context of recent tobacco control policies. Design and setting - For this descriptive study, age-standardised mortality rates per 100?000 person-years of LC for 185 countries by sex were obtained from the GLOBOCAN 2020 database and stratified by Human Development Index (HDI). LC deaths were projected to 2040 based on demographic changes alongside scenarios of annually increasing, stable or decreasing rates from the baseline year of 2020. Results - LC mortality rates exhibited marked variations by geography and sex. Low HDI countries, many of them within sub-Saharan Africa, tend to have low levels of mortality and an upward trend in LC deaths is predicted for both sexes until 2040 according to demographic projections, irrespective of trends in rates. In very high HDI countries, including Europe, Northern America and Australia/New Zealand, there are broadly decreasing trends in men whereas in women, rates are still increasing or reaching a plateau. Conclusion - The current and future burden of LC in a country or region largely depends on the present trajectory of the smoking epidemic in its constituent populations, with distinct gender differences in smoking patterns, both in transitioning and transitioned countries. Further elevations in LC mortality are expected worldwide, raising important social and political questions, especially in low-income and middle-income countries.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	BMJ Open. - 13 : 5 (2023), p. 1-8. -
További szerzők:	Morgan, Eileen Vignat, Jerome Laversanne, Mathieu Pizzato, Margherita Rumgay, Harriet Singh, Deependra Nagy Péter (1976-) (vegyész) Kenessey István Soerjomataram, Isabelle Bray, Freddie
Pályázati támogatás:	TKP2021-EGA-44 Egyéb 2022-2.1.1-NL-2022-00010 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
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