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001-es BibID:	BIBFORM136538
Első szerző:	Kovács Máté (állattenyésztési tudományok, PhD hallgató)
Cím:	Population structure and genetic diversity among Lipizzan mare families in Hungary based on microsatellite genotyping / Máté Kovács, Bettina Hegedűs, Sándor Mihók, Renáta Knop, Csaba Szabó, János Posta
Dátum:	2026
ISSN:	2076-2615
Megjegyzések:	The conservation of genetic diversity in historically structured horse breeds requires fine-scale population genetic evaluation beyond conventional pedigree-based approaches. The present study assessed genetic diversity, population structure, and mare family differentiation in a Lipizzan horse population using 16 ISAG/FAO-recommended microsatellite markers. A total of 172 mares representing 29 mare families were genotyped. All loci were polymorphic, with a mean number of alleles per locus of 6.69 and a mean effective number of alleles of 3.56. The average polymorphism information content (PIC = 0.66) indicated high marker informativeness. Mean observed heterozygosity was slightly lower than expected heterozygosity, although the overall negative inbreeding coefficient suggested general heterozygote excess and low population-level inbreeding whilst the genetic differentiation among mare families was moderate. The principal components and the STRUCTURE analysis indicated admixture among mare families. Seven private alleles were detected across six loci, highlighting the presence of rare lineage-specific variants. These findings emphasize the importance of mare family-based analyses for identifying hidden genetic structures that may not be captured by population-level averages. The integration of microsatellite based diversity evaluation provides a robust framework for de-signing sustainable breeding and conservation strategies aimed at preserving both overall variability and rare lineage specific genetic components.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk gene conservation breeding management population structure genetic differentiation Lipizzan
Megjelenés:	Animals. - 16 : 7 (2026), p. 1-21. -
További szerzők:	Hegedűs Bettina (1995-) (mezőgazdasági biotechnológus) Mihók Sándor (1950-) (agrármérnök) Knop Renáta (1983-) (állatorvos) Szabó Csaba (1968-) (agrármérnök) Posta János (1978-) (informatika tanár, agrármérnök)
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001-es BibID:	BIBFORM106307
035-os BibID:	(WoS)000839059400001 (Scopus)85136505221
Első szerző:	Lugata, James Kachungwa (Ph.D hallgató)
Cím:	Effects of DL and L-Methionine on Growth Rate, Feather Growth, and Hematological Parameters of Tetra-SL Layers from 1-28 Days of Age / James Kachungwa Lugata, János Oláh, Xénia Erika Ozsváth, Renáta Knop, Eszter Angyal, Csaba Szabó
Dátum:	2022
ISSN:	2076-2615
Megjegyzések:	The study was carried out to determine whether sources or levels of methionine (Met) affect the health status of Tetra-SL (TSL) chicks by examining growth performance, feather growth, and hematological parameters. A total of ninety-six (96) day-old (44.2 +/- 0.18 g lw) TSL chicks were randomly allotted to six treatment groups (three levels for each DL and L-Met source) with four replicates of four chicks each. Chicks were fed ad libitum diets supplemented with 90, 100, and 110% of methionine requirements for four weeks after hatch. The parameters examined are bodyweight (BW), average daily gain (ADG), feather length (FL), and hematological parameters, including: red blood cell (RBC) count, hemoglobin (Hb) concentration in the blood, hematocrit (Ht; %), number of white blood cells (WBC), platelet count, mean corpuscular volume of red blood cells (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), lymphocyte (LYM), mid-range (MID), and granulocyte (GRAN). There was no significant effect of Met sources and levels on BW, ADG, and FL of TSL chicks for the first four weeks of rearing. The RBC, Hb, Ht, WBC, LYM, MID, and GRAN values of TSL chicks were statistically influenced by dietary Met sources and Met levels (p < 0.05). Among the treatment groups, the number of white blood cells (WBC) on 90% DL-Met was the lowest. WBC, RBC, Hb, and Ht were higher from chicks that received 100% DL-Met than all other levels, regardless of the Met sources. The MCV, MCH, and MCHC values were not affected by either Met source or levels or their interactions. Met source and level interactively affected the Ht, WBC, LYM %, and GRAN values of TSL chicks (p < 0.05). The platelet number was affected by Met source only (p < 0.05) with chicks receiving L-Met source having more than twofold higher platelet values than DL-Met source. In conclusion, varying Met levels by +/- 10% of the requirement does not adversely affect the growth performance, feather growth, and hematological parameters of TSL chicks reared for up to four weeks of age. DL-Met increased the body weight and improved the white blood cells, red blood cells, and hematocrit at 28 days after hatch. DL-Met showed similar biological efficacy as L-Met for body weight and feather growth but not for the hematological parameters.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk DL-methionine L-methionine blood hematology Tetra-SL
Megjelenés:	Animals. - 12 : 15 (2022), p. 1-11. -
További szerzők:	Oláh János (1976-) (állattenyésztés) Ozsváth Xénia Erika Knop Renáta (1983-) (állatorvos) Angyal Eszter (1994-) (állatorvos doktor) Szabó Csaba (1968-) (agrármérnök)
Pályázati támogatás:	EFOP-3.6.3-VEKOP-16-2017-00008 EFOP-VEKOP
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001-es BibID:	BIBFORM123835
035-os BibID:	(WoS)001311042300001 (Scopus)85203628397
Első szerző:	Ndunguru, Sawadi Fransisco (1980-)
Cím:	Embryonic Leucine Promotes Early Postnatal Growth via mTOR Signalling in Japanese Quails / Sawadi F. Ndunguru, Gebrehaweria K. Reda, Brigitta Csernus, Renáta Knop, James K. Lugata, Csaba Szabó, Ádám Z. Lendvai, Levente Czeglédi
Dátum:	2024
ISSN:	2076-2615
Megjegyzések:	However, the specific mechanisms by which nutrients influence avian growth remain largely unknown. Amino acids can directly interact with the nutrient-sensing pathways, such as the insulin-like growth factor 1 (IGF-1)/mechanistic target of rapamycin (mTOR) pathways, which are known to regulate growth. We examined the effects of embryonic leucine on gene expression and phenotypic growth in Japanese quails by injecting 2.5 mg leucine or saline (control) into Japanese quail eggs on the tenth day of incubation and incubating them under standard conditions. The treatment groups had similar hatching success and size at hatching. However, between 3 and 7 days post-hatching, quails treated with embryonic leucine showed increased growth in body mass and wing, tarsus, head, and intestinal lengths, lasting up to 21 days. The hepatic expression of IGF1, IGF1R, mTOR, and RPS6K1 was upregulated in leucine-treated quails, while the expression of FOXO1 remained unaffected. In conclusion, a subtle increase in embryonic leucine may induce developmental programming effects in Japanese quail by interacting with the IGF-1/mTOR nutrient-sensing pathway to promote growth. This study highlights the role of embryonic amino acids as crucial nutrients for enhancing growth. It provides valuable insight into nutrient intervention strategies during embryonic development to potentially improve poultry growth performance.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk birds physiology nutrition amino acid mechanistic target of rapamycin
Megjelenés:	Animals. - 14 : 17 (2024), p. 1-16. -
További szerzők:	Reda, Gebrehaweria Kidane (1986-) (Animal Sceince) Csernus Brigitta (1991-) (élelmiszerbiztonsági és -minőségi mérnök) Knop Renáta (1983-) (állatorvos) Lugata, James Kachungwa (1992-) (Ph.D hallgató) Szabó Csaba (1968-) (agrármérnök) Lendvai Ádám Zoltán (1977-) (biológus) Czeglédi Levente (1977-) (agrármérnök)
Pályázati támogatás:	K139021 OTKA
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