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001-es BibID:	BIBFORM117684
Első szerző:	Jolji, Maria (Phd hallgató)
Cím:	Development and comparative analysis of protein-polyphenol-fibre bars as nutritional supplements suitable for healthy senior consumers / M. Jolji, B. Pecsenye, Z. Mposula, A. Aleya, T. Kiss, E. Mathé
Dátum:	2023
ISSN:	1844-7449 2066-7744
Megjegyzések:	The number of elderly people is steadily increasing in developing countries though the specific age-related challenges of nutrition fail to get properly addressed in the case of senior citizens. Accordingly, we have developed protein-polyphenol dietary fibre (PPF) bars using two kinds of protein mixtures (1 and 2) and some food additives, such as the banana powder, freeze-dried strawberries, coconut powder, Dutch cacao powder, and vanilla cookies, as they can interfere with the texture of bars and the flavour as well. The used food additives are also a source of polyphenols and dietary fibres that would enhance the nutritive values of the bars. The texture properties, such as hardness and cutting force, were assessed, and the results indicated a significant difference (P < 0.05) among the bars, offering important hints about their suitability for the elderly. Also, significant differences were observed for the polyphenol content of the bars that would stress their increased nutritional relevance too. On average, the sensorial evaluation showed the developed bars of moderate acceptability, while Bar 3 and 6 had the highest scores for colour, texture, flavour, and aroma. Conversely, Bar 1 recorded the lowest values for all assessed criteria. Interestingly, Bar 3 with freeze-dried strawberries and Bar 6 with Dutch cacao powder were the most appreciated flavours and contained in the range of 25-28% protein, 17-23% carbohydrate, 15-21% lipids, and 15-23% dietary fibre, which also indicates their nutritionally balanced nature. Furthermore, the above-mentioned macronutrient content ensures approximately 400 Kcal/100g per PPF bar, while through their polyphenol and flavonoid yield their health-promoting effect gets substantiated.
Tárgyszavak:	Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk protein-polyphenol-fibre protein bar nutritional supplement senior consumer antioxidant activity
Megjelenés:	Acta Universitatis Sapientiae, Alimentaria. - 16 : 1 (2023), p. 103-125. -
További szerzők:	Pecsenye Bence (1992-) (vegyészmérnök, vegyész analitikus) Mposula, Zibuyile (1991-) (phd hallgató) Alaya, Amina (1992-) (PhD student) Kiss T. Máthé Endre (1964-) (genetikus, molekuláris sejtbiológus)
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001-es BibID:	BIBFORM117685
Első szerző:	Mposula, Zibuyile (phd hallgató)
Cím:	Lifestyle and socio-economic inequalities in diabetes prevalence in Madadeni Township, South Africa / Mposula, Zibuyile Angel, Pacza Tünde, Szepesi Judith, Máthé Endre
Dátum:	2023
ISSN:	2062-0284
Megjegyzések:	Rapid urbanization, social inequalities, sedentary lifestyles, and unhealthy eating habits are contributing factors to the increasing prevalence of diabetes in South Africa. Data was collected from 99 residents in Madadeni, South Africa. The analysis was conducted using Microsoft Excel and the Statistical Package for Social Sciences (SPSS) V.29. The sample had a mean age of 67.4±9.4 years, with 73.74% females and 26.26% males. Majority had Grade 10 as their highest level of education (31.31%) and were retired (51.52%). The average number of household members was 6.35±2.57. The average estimated total income was R5681.82±R2585.73 per month, with 2.13±0.92 members contributing to household income. Majority (72.72%) had T2DM, while 27.27% had T1DM. The quantitative results highlight the importance of increasing awareness and providing health education to empower the affected population with self-management knowledge.
Tárgyszavak:	Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény hazai lapban folyóiratcikk diabetes health status South African townships
Megjelenés:	Acta medicinae et sociologica. - 14 : 37 (2023), p. 5-21. -
További szerzők:	Pacza Tünde (1967-) (alkalmazott matematikus, informatikus, prediktív táplálkozástudomány) Szepesi Judith Máthé Endre (1964-) (genetikus, molekuláris sejtbiológus)
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001-es BibID:	BIBFORM136775
Első szerző:	Pecsenye Bence (vegyészmérnök, vegyész analitikus)
Cím:	Making Sense of Developmental Kinetics Under High-Sugar Stress : Mathematical Modeling of Phenotypic Plasticity in Drosophila melanogaster / Bence Pecsenye, Maha Rockaya, Tünde Pacza, Zibuyile Mposula, Endre Máthé
Dátum:	2026
ISSN:	2072-6643
Megjegyzések:	Background/Objectives: Although Drosophila melanogaster is widely used in genetics and nutrition research, developmental kinetics are rarely analyzed using formal mathematical modeling. Most dietary studies present developmental curves without rigorous fitting, limiting quantitative interpretation. This study applies and compares three primary models, as well as develops secondary models, to characterize the effects of high-sugar diets on egg-to-adult (life cycle) development. Methods: Standardized husbandry and an embryo-to-pupa feeding assay were performed across 11 sucrose concentrations. Synchronized embryo collection and high-resolution monitoring were used for this assay. Three primary models?dose?response, Gompertz, and logit-based linearization?were fitted to developmental curves to extract timing (tmid) and synchrony (sdvp) parameters. Secondary modeling was used to evaluate how these parameters change with respect to sucrose concentration. A custom VBA implementation of the Levenberg?Marquardt algorithm was used for fitting. Results: Increasing sucrose concentration markedly delayed pupariation and reduced viability at the highest levels. All models showed increasing tmid and decreasing sdvp with rising sugar concentration, with the Gompertz model providing the best overall performance. Secondary modeling revealed a consistent bilinear response with a breakpoint at 0.52-0.62 M, separating low-, medium-, and high-sucrose conditions. Reduced sampling frequency decreased model robustness, while twice-daily observations remained sufficient. Conclusions: Mathematical modeling provides a robust, practical framework for quantifying the effects of diet on D. melanogaster development. The Gompertz model provided the best fit and yielded biologically interpretable parameters. The bilinear secondary model effectively captured sucrose-dependent stress responses and quantified plasticity through environment-dependent changes in developmental timing and synchrony. Overall, this work establishes a quantitative practical framework for modeling developmental kinetics under nutritional perturbations, and the approach can be extended with additional secondary environmental factors to improve predictive analyses of nutritional effects.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Drosophila melanogaster nutritional modeling sugar stress sucrose life cycle developmental kinetics
Megjelenés:	Nutrients. - 18 : 8 (2026), p. 1-17. -
További szerzők:	Rockaya, Maha (1993-) (PhD hallgató) Pacza Tünde (1967-) (alkalmazott matematikus, informatikus, prediktív táplálkozástudomány) Mposula, Zibuyile (1991-) (phd hallgató) Máthé Endre (1964-) (genetikus, molekuláris sejtbiológus)
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