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1.
001-es BibID:
BIBFORM134641
Első szerző:
Al Ashkar, Habib (népegészségügyi szakember)
Cím:
Association of physical activity domains and intensity with acute heart rate response to exercise / Al Ashkar H., Kovács N., Veres-Balajti I., Ádány R., Pikó P.
Dátum:
2025
ISSN:
1101-1262
Megjegyzések:
Background The positive association between physical activity (PA) and heart rate (HR) related cardiovascular (CV) fitness and CV risk is well established, but it is less well known how the type and intensity of PA have influence on the efficacy of the risk reduction. The aim of the present study was to investigate the association between CV fitness and three intensity categories of PA in four domains in the Hungarian population. Methods Data for our study were obtained from a cross-sectional survey (n?=?665) conducted in Hungary in 2018. Individual PA was assessed using the IPAQ long form and expressed as the metabolic equivalent of task minutes per week for light, moderate and vigorous activities for total and each domain (work, transport, domestic and gardening - dom. & gard., leisure-time - LTPA). CV fitness was assessed using the YMCA 3-minute step test, with HR measured at rest (HRrest) and immediately after exercise (HRaft) and their difference (?HR) was calculated. Multiple regression analysis was used for the statistical analyses. Results Total PA (B=-0.001; p?<?0.001), its vigorous (B=-0.001; p?=?0.001) and moderate (B=-0.001; p?<?0.001) intensity forms, and LTPA (B=-0.002; p?<?0.001) showed a significant association with both HRaft and ?HR, whereas dom. & gard. domain (B=-0.001; p?=?0.010) is only significantly associated with ?HR. Vigorous intensity form of dom. & gard. (B=-0.002; p?=?0.006) and moderate intensity form of LTPA (B=-0.004; p?<?0.001) showed individually significant associations with HRaft but not with ?HR. Transport by bicycle was the only form of PA that showed a significant association with both HRaft (B=-0.004; p?<?0.001) and ?HR (B=-0.003; p?=?<0.001). Conclusions Based on our results, among the domains of PA, dom. & gard. and LTPA, both moderate and vigorous intensity forms, as well as the use of bicycles for transport showed the strongest association with favourable CV fitness, and their promotion in public health interventions is recommended. Key messages ??Recommendations should consider that not all forms of physical activity significantly improve individual cardiovascular fitness. ??Interventions targeting the improvement of cardiovascular fitness should improve physical activity in leisure time and the use of bicycles for transport.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idézhető absztrakt
folyóiratcikk
Megjelenés:
European Journal Of Public Health. - 35 : Supplement 4 (2025), p. iv705-iv706. -
További szerzők:
Kovács Nóra (1989-) (népegészségügyi szakember)
Veres-Balajti Ilona (1965-) (gyógytornász, egészségfejlesztő)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pikó Péter (1987-) (biológus)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
2.
001-es BibID:
BIBFORM132164
Első szerző:
Al Ashkar, Habib (népegészségügyi szakember)
Cím:
Association of HDL-C and its subfraction profile with heart rate response to exercise / Al Ashkar Habib, Kovács Nóra, Veres-Balajti Ilona, Seres Ildikó, Paragh György, Ádány Róza, Pikó Péter
Dátum:
2025
ISSN:
0021-9150
Megjegyzések:
Background and Aims: High-density lipoproteins (HDL) are a heterogeneous group of plasma molecules that can be divided into subfractions based on their characteristics. Although HDL subfractions vary widely in size, density, and function, their association with cardiovascular outcomes remains complex and partly unknown. Heart rate response to physical activity (HRR) is a well-known indicator of individual cardiovascular fitness. The present study aimed to investigate the association between HRR and HDL subfraction profile in 304 individuals from the Hungarian population. Methods: HDL was divided into ten subfractions using the Lipoprint HDL? system. The YMCA 3-minute step test was used to assess the individual HRR by measuring the heart rate at four-time points: before the exercise (resting HR - HRrest), immediately (HRexe), 5 minutes (HR5min) and 10 minutes (HR10min) after exercise. In addition, acute HRR (?HR) was calculated (HRexe-HRrest). Multiple linear regression was used to examine the association between HDL subfraction profile and HRR. Results: The distribution of HDL-3 (BHRexe=-1.26, p =0.020; BHR5min=-0.70, p=0.048; B?HR=-1.21, p=0.035), HDL-4 (BHRexe=-1.86, p=0.040; BHR5min=-0.92, p=0.048; B?HR=-1.88, p=0.030), and HDL-5 (BHRexe=-3.34, p=0.017; BHR5min=-1.84, p=0.041; B?HR=-3.32, p=0.037) showed a significant negative association, whereas HDL-7 (BHRexe=2.64, p=0.025; BHR5min=1.37, p=0.045; B?HR=2.41, p=0.034), HDL-8 (BHRexe=2.87, p =0.030; BHR5min=1.70, p=0.035; B?HR=2.48, p=0.035), HDL-9 (BHRexe=3.10, p =0.010; BHR5min=2.18, p=0.013; B?HR=3.04, p=0.045), and HDL-10 (BHRexe=0.95, p =0.035; BHR5min=0.67, p=0.020; B?HR=0.71, p=0.049) were positively associated with HRR. However, there was no significant change in the concentration of HDL-C and its subfractions in mmol/L in relation to HRR. Conclusions: Our results suggest that a more optimal (smaller) heart rate change in response to physical activity is associated with a more favourable distribution of the HDL subfraction profile, i.e. a significant increase in the proportion of smaller HDL subfractions and a decrease in the proportion of larger subfractions. In contrast, no significant quantitative changes were observed in HDL-C and its subfractions.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idézhető absztrakt
folyóiratcikk
HDL
Cardiovascular risk
heart rate response to exercise
HDL-C subfraction profile
Cardiorespiratory fitness
Lipid profile
Megjelenés:
Atherosclerosis. - 407 : Suppl. (2025), p. 57. -
További szerzők:
Kovács Nóra (1989-) (népegészségügyi szakember)
Veres-Balajti Ilona (1965-) (gyógytornász, egészségfejlesztő)
Seres Ildikó (1954-) (biokémikus)
Paragh György (1953-) (belgyógyász)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pikó Péter (1987-) (biológus)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
3.
001-es BibID:
BIBFORM132287
Első szerző:
Al Ashkar, Habib (népegészségügyi szakember)
Cím:
The Impact of Smoking-Associated Genetic Variants on Post-Exercise Heart Rate / Al Ashkar Habib, Kharrat Helu Nihad, Kovacs Nora, Fiatal Szilvia, Adany Roza, Piko Peter
Dátum:
2025
ISSN:
1661-6596 1422-0067
Megjegyzések:
Smoking has a well-established impact on cardiovascular health, notably through ele- vated resting heart rate and impaired autonomic regulation?both key risk factors. While nicotine's acute effects are well documented, the influence of smoking-related genetic variants on heart rate (HR) responses remains unclear. This study investigated the asso- ciation between selected smoking-related single nucleotide polymorphisms (SNPs) and HR dynamics following physical exertion. A total of 661 Hungarian adults completed the YMCA 3 min step test, with HR measured at rest, immediately post-exercise, and during recovery at 5 and 10 min. Key indices included post-exercise HR (HRaft), HR change (?HR), maximum HR percentage (HRmax%), and heart rate recovery coefficient (HRR). Genetic analysis focused on nine SNPs previously linked to smoking behaviours, with a composite genetic risk score derived from the three most influential variants (rs2235186, rs4142041, and rs578776). Associations were examined using adjusted linear regression. No significant relationship was found between any individual SNP and resting HR. However, rs2235186, rs4142041, and rs578776 were consistently associated with elevated HRaft, increased ?HR, higher HRmax%, and slower HRR. The genetic risk score showed significant correlations with all post-exercise HR measures, suggesting a cumulative genetic effect. These findings indicate that smoking-related genetic predisposition may influence autonomic cardiovascu- lar responses to physical activity. Although resting HR remains unaffected, specific SNPs are linked to post-exercise HR dynamics and recovery, highlighting the potential value of genetic screening in personalised cardiovascular risk assessment among smokers
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
smoking
single nucleotide polymorphisms
heart rate recovery
cardiovascular risk
genetic predisposition
YMCA step test
genetic risk score
Megjelenés:
International Journal Of Molecular Sciences. - 26 : 18 (2025), p. 1-17. -
További szerzők:
Kharrat Helu, Nihad (1992-)
Kovács Nóra (1989-) (népegészségügyi szakember)
Fiatal Szilvia (1978-) (epidemiológus, népegészségügyi szakember)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pikó Péter (1987-) (biológus)
Pályázati támogatás:
GINOP-2.3.2-15-2016-00005
GINOP
TK2016-78
MTA
Hungarian Research Network?HUN-REN (TKCS-2021/32)
Egyéb
Project No. 135784 - National Research, Development, and Innovation Fund of Hungary
Egyéb
National Laboratory for Health Security Hungary (RRF-2.3.1-21-2022-00006)
Egyéb
Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (BO/00513/23/5)
Egyéb
EKÖP-24-4 University Research Scholarship Program of the Ministry for Culture and Innovation from the source of the National Research, Development and Innovation Fund
Egyéb
Stipendium Hugaricum Scholarship Program, provided by the Tempus Public Foundation and the Hungarian Government
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
4.
001-es BibID:
BIBFORM123542
035-os BibID:
(Scopus)85202750993 (WoS)001307359100001
Első szerző:
Al Ashkar, Habib (népegészségügyi szakember)
Cím:
Association of CETP Gene Polymorphisms and Haplotypes with Acute Heart Rate Response to Exercise / Al Ashkar Habib, Kovács Nóra, Veres-Balajti Ilona, Ádány Róza, Pikó Péter
Dátum:
2024
ISSN:
1661-6596 1422-0067
Megjegyzések:
Polymorphisms in the cholesteryl ester transfer protein (CETP) gene are known to be strongly associated with increased cardiovascular risk, primarily through their effects on the lipid profile and consequently on atherosclerotic risk. The acute heart rate response (AHRR) to physical activity is closely related to individual cardiovascular health. This study aimed to investigate the effect of CETP gene polymorphisms on AHRR. Our analysis examines the association of five single nucleotide polymorphisms (SNPs; rs1532624, rs5882, rs708272, rs7499892, and rs9989419) and their haplotypes (H) in the CETP gene with AHRR in 607 people from the Hungarian population. Individual AHRR in the present study was assessed using the YMCA 3-min step test and was estimated as the difference between resting and post-exercise heart rate, i.e., delta heart rate (Delta HR). To exclude the direct confounding effect of the CETP gene on the lipid profile, adjustments for TG and HDL-C levels, next to conventional risk factors, were applied in the statistical analyses. Among the examined five SNPs, two showed a significant association with lower Delta HR (rs1532624-C-dominant: B = -8.41, p < 0.001; rs708272-G(dominant): B = -8.33, p < 0.001) and reduced the risk of adverse AHRR (rs1532624-C-dominant: OR = 0.44, p = 0.004; rs708272-G(dominant): OR = 0.43, p = 0.003). Among the ten haplotypes, two showed significant association with lower Delta HR (H3-CAGCA: B = -6.81, p = 0.003; H9-CGGCG: B = -14.64, p = 0.015) and lower risk of adverse AHRR (H3-CAGCA: OR = 0.58, p = 0.040; H9-CGGCG: OR = 0.05, p = 0.009) compared to the reference haplotype (H1-AGACG). Our study is the first to report a significant association between CETP gene polymorphisms and AHRR. It also confirms that the association of the CETP gene with cardiovascular risk is mediated by changes in heart rate in response to physical activity, in addition to its effect on lipid profile.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
cardiovascular risk
haplotype
acute heart rate response
cholesteryl ester transfer protein
genomics
Megjelenés:
International Journal Of Molecular Sciences. - 25 : 16 (2024), p. 1-10.-
További szerzők:
Kovács Nóra (1989-) (népegészségügyi szakember)
Veres-Balajti Ilona (1965-) (gyógytornász, egészségfejlesztő)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pikó Péter (1987-) (biológus)
Pályázati támogatás:
GINOP-2.3.2-15-2016-00005
GINOP
TK2016-78
MTA
Hungarian Research Network-HUN-REN (TKCS-2021/32)
Egyéb
National Research, Development, and Innovation Fund of Hungary K_20 programme
Egyéb
National Laboratory for Health Security Hungary (RRF-2.3.1-21-2022-00006)
Egyéb
ÚNKP-23-5-DE-494
Egyéb
Janos Bolyai Research Scholarship (BO/00513/23/5)
MTA
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
5.
001-es BibID:
BIBFORM100963
035-os BibID:
(Scopus)85126518868 (WOS)000775307600001
Első szerző:
Bácsné Bába Éva (bölcsésztanár, szakközgazda)
Cím:
Physical Activity Pattern Characterized by Domains and Dimensions of the Roma Population in Comparison with That of the General Population in Northeast Hungary / Bácsné Bába Éva, Pikó Péter, Müller Anetta, Ráthonyi Gergely, Balogh Péter, Kósa Zsigmond, Kovács Nóra, Sándor János, Ádány Róza, Bács Zoltán
Dátum:
2022
ISSN:
1661-7827 1660-4601
Megjegyzések:
Our study focuses on examining physical activity, as one of the most influential health determinants by domains and dimensions among Roma, the largest vulnerable ethnic minority in Europe. The study was carried out on a sample representative of the Hungarian Roma (HR) population (n = 350) living in segregated colonies in Northeast Hungary in comparison with the Hungarian general (HG) population sample (n = 343) from the same region. Data were collected using the International Physical Activity Questionnaire (IPAQ) long-form and physical activity was quantified as MET-min/week. Scores were calculated for walking, moderate and vigorous-intensity activities for each domain (work, transport, domestic and gardening, leisure) and as an overall total. The HR population-similarly to the HG-is characterized by moderate or high physical activity; however, this level is achieved by work and housework/gardening instead of leisure time activities, which is worryingly low among HR females, but its prevalence is significantly (p < 0.001) lower in both sexes than among the HG population in the vigorous activity category. HR men move (walk and cycle) significantly more during transport than HG men. Our results may direct the attention of decision-makers to improve the health of Roma by increasing leisure-time physical activity.
Tárgyszavak:
Társadalomtudományok
Gazdálkodás- és szervezéstudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:
International Journal of Environmental Research and Public Health. - 19 : 6 (2022), p. 1-14. -
További szerzők:
Pikó Péter (1987-) (biológus)
Müller Anetta Éva (1973-)
Ráthonyi Gergely Gábor (1985-) (informatikus agrármérnök)
Balogh Péter (1970-) (agrármérnök)
Kósa Zsigmond (1953-) (orvos)
Kovács Nóra (1989-) (népegészségügyi szakember)
Sándor János (1966-) (orvos-epidemiológus)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Bács Zoltán (1969-) (agrármérnök)
Pályázati támogatás:
GINOP-2.3.2-15-2016-00005
GINOP
TK2016-78
MTA
ÚNKP-21-4
Egyéb
Nemzeti Kutatási, Fejlesztési és Innovációs Alap, Projekt azonosító: 135784
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
6.
001-es BibID:
BIBFORM132036
Első szerző:
Kharrat Helu, Nihad
Cím:
Lactase Persistence-Associated rs4988235 Polymorphism : a Novel Genetic Link to Cardiovascular Risk via Modulation of ApoB100 and ApoAI / Kharrat Helu Nihad, Al Ashkar Habib, Kovacs Nora, Adany Roza, Piko Peter
Dátum:
2025
ISSN:
2072-6643
Megjegyzések:
Background/Objectives: As part of the human adaptation to dairy consumption, the presence of the rs4988235-T variant in the MCM6 gene primarily determines lactase persistence in adult European populations, increasing the expression of the lactase-encoding LCT gene. Carriers of the C/C variant are lactose intolerant, while carriers of the T/T or T/C variant have persistent lactase enzyme activity and are able to digest lactose in adulthood. While the association between lactose intolerance and increased cardiovascular risk (CVR) is well-known, the underlying causes have only been partly explored. The present study aimed to investigate the association of rs4988235 polymorphism with significant lipids affecting cardiovascular health and estimated CVR. Methods: The rs4988235 polymorphism was genotyped in 397 subjects from the general Hungarian population and 368 individuals from the Roma population. To characterize the overall lipid profile, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), apolipoprotein AI (ApoAI), and apolipoprotein B100 (ApoB100) levels were measured, and their ratios (TG/HDL-C, LDL-C/HDL-C, and ApoB100/ApoAI) were calculated. Cardiovascular risk was estimated using the Framingham Risk Score (FRS), Pooled Cohort Equations (PCE), Revised Pooled Cohort Equations (RPCE), and the Systematic Coronary Risk Evaluations (SCORE and SCORE2) algorithms. Adjusted linear and logistic regression analyses were performed, with p < 0.05 considered significant. Results: The Roma population had a significantly higher prevalence of the C/C genotype than the general population (65.5% vs. 40.3%, respectively). The results of the adjusted linear regression analysis showed a significant association between the C/C genotype and higher LDL-C level (B = 0.126, p = 0.047) and ApoB100 level (B = 0.046, p = 0.013), as well as a higher LDL-C/HDL-C ratio (B = 0.174, p = 0.021) and a higher ApoB100/ApoAI ratio (B = 0.045, p = 0.002), as well as a lower HDL-C level (B = ?0.041, p = 0.049). The C/C genotype was also significantly associated with an increased cardiovascular risk (CVR) as estimated by the SCORE (B = 0.235, p = 0.034), SCORE2 (B = 0.414, p = 0.009), PCE (B = 0.536, p = 0.008), and RPCE (B = 0.289, p = 0.045) but not the FRS. After adjusting the statistical model further for ApoAI and ApoB100 levels, the significant correlation with the risk estimation algorithms disappeared (SCORE: p = 0.099; SCORE2: p = 0.283; PCE: p = 0.255; and RPCE: p = 0.370). Conclusions: Our results suggest that the C/C genotype of rs4988235 is associated with significantly higher ApoB100 and lower ApoAI levels and consequently higher ApoB100/ApoAI ratios, potentially contributing to an increased risk of cardiovascular disease. The results of the statistical analyses suggest that the association between lactose intolerant genotype and cardiovascular risk may be mediated indirectly via modification of the apolipoprotein profile.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
lactase persistence
polymorphism
SNP
Roma
Hungarian
cardiovascular risk
SCORE
SCORE2
Framingham Risk Score
ACC/AHA Pooled Cohort Equations
Megjelenés:
Nutrients. - 17 : 17 (2025), p. 1-19. -
További szerzők:
Al Ashkar, Habib (1998-) (népegészségügyi szakember)
Kovács Nóra (1989-) (népegészségügyi szakember)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pikó Péter (1987-) (biológus)
Pályázati támogatás:
GINOP-2.3.2-15-2016-00005
GINOP
TK2016-78
MTA
TKCS-2021/32
Egyéb
135784
Egyéb
RRF-2.3.1-21-2022-00006
Egyéb
BO/00513/23/5
Egyéb
EKÖP-24-4
Egyéb
Stipendium Hungaricum Scholarship Programme
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
7.
001-es BibID:
BIBFORM058659
Első szerző:
Kiss Tímea (molekuláris biológus)
Cím:
The role of osteopontin expression in melanoma progression / Timea Kiss, Szilvia Ecsedi, Laura Vizkeleti, Viktoria Koroknai, Gabriella Emri, Nora Kovács, Roza Adany, Margit Balazs
Dátum:
2015
ISSN:
1010-4283
Megjegyzések:
It was shown that osteopontin (OPN), a glycophosphoprotein, plays divergent roles in cancer progression. In addition to multiple intra- and extracellular functions, it facilitates migration of tumour cells, has crucial role in cell adhesion and is associated with increased metastasis formation. In previous studies, we performed global gene expression profiling on a series of primary melanoma samples and found that OPN was significantly overexpressed in ulcerated melanomas. The major purpose of this study was to define OPN expression in primary melanomas with differing biological behaviours. OPN mRNA expression was analysed by quantitative reverse transcription polymerase chain reaction (qRT-PCR) in primary melanoma tissues. Immunohistochemistry was performed using a tissue microarray. Cox regression tests were used for survival analysis. Greater than 50 % of the tissues exhibited high protein expression that was significantly associated with tumour thickness and metastasis. OPN mRNA expression was significantly increased in thicker melanomas and lesions with an ulcerated surface. Increased expression was primarily detected in advanced-stage tumours. A multivariate Cox regression analysis revealed that high OPN expression, tumour thickness and metastasis were significantly associated with reduced relapse-free survival. In summary, high OPN mRNA and protein expression were associated with a less favourable clinical outcome of primary melanoma patients. We determined that OPN is a significant predictive factor for the survival of primary melanoma patients. Based on our and others data, the high expression of OPN may have a crucial stimulatory role in tumour progression and metastasis formation, which, thus, have been proposed as potential targets for cancer diagnosis and therapy
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Melanoma progression
Osteopontin
Protein expression
Tissue microarray
Megjelenés:
Tumor Biology. - 36 : 10 (2015), p. 7841-7847. -
További szerzők:
Ecsedi Szilvia (1982-) (molekuláris biológus, genetikus)
Vízkeleti Laura (1984-) (molekuláris biológus, genetikus)
Koroknai Viktória (1986-) (molekuláris biológus)
Emri Gabriella (1972-) (bőrgyógyász, allergológus, onkológus)
Kovács Nóra (1989-) (népegészségügyi szakember)
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Balázs Margit (1952-) (sejtbiológus, molekuláris genetikus)
Pályázati támogatás:
K112327
OTKA
TÁMOP-4.2.2/B-10/1-2010-0024
TÁMOP
Egészségtudományok Doktori Iskola
4.2.4.A/2-11/1-2012-0001
TÁMOP
TÁMOP-4.2.2.A-11/1/KONV-2012-0031
TÁMOP
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
8.
001-es BibID:
BIBFORM127299
035-os BibID:
(wos)001407507200001 (scopus)85217219518
Első szerző:
Kovács Nóra (népegészségügyi szakember)
Cím:
Attitudes towards healthy eating and its determinants among older adults in a deprived region of Hungary : implications for the National Healthy Aging Program / Kovacs Nora, Biro Eva, Piko Peter, Ungvari Zoltan, Adany Roza
Dátum:
2025
ISSN:
2509-2715 2509-2723
Megjegyzések:
A healthy diet is a key determinant of successful aging. However, the psychological, social, and physiological changes associated with ageing often disrupt dietary behaviours. Hungary has one of the highest rates of chronic age-related diseases in the European Union, exacerbated by unhealthy dietary patterns and rapid population aging. This study evaluates attitudes and barriers to healthy eating among older adults in a socioeconomically disadvantaged region of Hungary, identifying determinants of these attitudes across different age groups. A cross-sectional survey sampled 678 adults aged 18 and older from Northeast Hungary, assessing their beliefs on healthy eating through an attitude score (range: 9-45). Multivariate regression analyses were conducted to explore relationships between mental health, self-perceived health, and attitudes toward healthy eating. The mean attitude score was 31.47 (+/- 5.14), with older adults (>= 65 years) showing significantly greater uncertainty about dietary choices. The cost of healthy food was the most frequently reported barrier, regardless of age. Regression results revealed that older adults with higher well-being (B = 0.03, p = 0.026), life satisfaction (B = 0.40, p = 0.005), and self-perceived health (fair: B = 2.20, p = 0.003; good/very good: B = 1.96, p = 0.031) were more likely to have positive attitudes toward healthy eating. These results emphasize the importance of addressing both mental and physical health in educational interventions to promote healthier diets. Tailored approaches addressing affordability and accessibility of healthy foods are critical to advancing Hungary's National Healthy Aging Program and mitigating dietary risk factors among vulnerable populations.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
healthy eating
attitude
barriers
mental health
ageing
Megjelenés:
GeroScience. - 47 : 4 (2025), p. 5695-5707. -
További szerzők:
Bíró Éva (1980-) (megelőző orvostan és népegészségtan szakorvos, egészségfejlesztő)
Pikó Péter (1987-) (biológus)
Ungvári Zoltán
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:
GINOP-2.3.2-15-2016-00005
GINOP
Hungarian Research Network-HUN-REN (TKCS-2021/32)
Egyéb
TK2016-78
MTA
National Research, Development, and Innovation Fund of Hungary Project No. 135784
Egyéb
National Laboratory for Health Security Hungary (RRF-2.3.1-21-2022-00006)
Egyéb
National Cardiovascular Laboratory Program (RRF-2.3.1-21-2022-00003)
Egyéb
TKP2021-NKTA-47
Egyéb
Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences
Egyéb
EKÖP-24-4 University Research Scholarship Program of the Ministry for Culture and Innovation from the source of the National Research, Development and Innovation Fund
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
9.
001-es BibID:
BIBFORM120985
035-os BibID:
(Scopus)85192239860 (WoS)001220197000001
Első szerző:
Kovács Nóra (népegészségügyi szakember)
Cím:
Age-related shifts in mental health determinants from a deprived area in the European Union : informing the national healthy aging program of Hungary / Nora Kovacs, Eva Biro, Peter Piko, Zoltan Ungvari, Roza Adany
Dátum:
2024
ISSN:
2509-2715 2509-2723
Megjegyzések:
Mental disorders are among the leading causes of disability worldwide, disproportionately affecting older people. This study aims to assess the mental health of elderly individuals living in a deprived region of Hungary, and to identify and estimate the weight of different determinants of mental health across different age groups. A cross-sectional study was conducted with randomly selected samples of individuals (n?=?860) aged 18 years and older in Northeast Hungary. The World Health Organization Well-Being Index (WHO-5), the single-item Life Satisfaction Scale, and the 12-item General Health Questionnaire (GHQ-12) were used to measure mental health of the participants. Multiple linear regression analysis was performed to measure the association between sociodemographic and health-related variables and mental health. Overall, the mean WHO-5 score was 69.2???18.1 and it showed a significant decrease by age (p?<?0.001), with the lowest score observed in aged 75 years and above (p?<?0.001). The mean life satisfaction score was 7.5???1.9 and it showed a significant decreasing trend over the life course (p?<?0.001). The highest level of psychological distress as assessed by GHQ-12 was observed in the group aged 75 years or older (11.5???6.0, p?<?0.001). Multiple linear regression indicated that self-reported financial status, social support, sense of control over their health, activity limitation and pain intensity were the most important determinants of mental health among older adults. Interventions to improve the mental health of older adults should focus on the positive impact of social support, the reduction of financial insecurity and the use of effective pain relief medications.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
ageing
life satisfaction
mental well-being
social support
Megjelenés:
GeroScience. - 46 (2024), p. 4793-4807. -
További szerzők:
Bíró Éva (1980-) (megelőző orvostan és népegészségtan szakorvos, egészségfejlesztő)
Pikó Péter (1987-) (biológus)
Ungvári Zoltán
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:
GINOP-2.3.2-15-2016-00005
GINOP
TK2016-78
MTA
Hungarian Research Network-HUN-REN (TKCS-2021/32)
Egyéb
National Laboratory for Health Security Hungary (RRF-2.3.1-21-2022-00006)
Egyéb
National Cardiovascular Laboratory Program (RRF-2.3.1-21-2022-00003)
Egyéb
TKP2021-NKTA-47
Egyéb
ÚNKP-23-5-DE-494
Egyéb
BO/00513/23/5
Egyéb
BO/00933/22/5
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
10.
001-es BibID:
BIBFORM115852
Első szerző:
Kovács Nóra (népegészségügyi szakember)
Cím:
Exploring health service utilization among elderly populations in Hungary : A comparison of rural and urban settings in the context of Unhealthy Ageing / Kovacs N., Piko P., Kolozsvari L., Kovacs E., Ungvari Z., Adany R.
Dátum:
2023
ISSN:
1101-1262
Tárgyszavak:
Orvostudományok
Egészségtudományok
idézhető absztrakt
folyóiratcikk
Megjelenés:
European Journal Of Public Health. - 33 : Supplement 2 (2023), p. ii69. -
További szerzők:
Pikó Péter (1987-) (biológus)
Kolozsvári László Róbert (1977-) (háziorvos)
Kovács Eszter (1972-) (háziorvostan szakorvos)
Ungvári Zoltán
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
11.
001-es BibID:
BIBFORM115171
035-os BibID:
(WoS)001081655000001 (Scopus)85173726282
Első szerző:
Kovács Nóra (népegészségügyi szakember)
Cím:
Comparative analysis of health status and health service utilization patterns among rural and urban elderly populations in Hungary : a study on the challenges of unhealthy aging / Kovacs Nora, Piko Peter, Juhasz Attila, Nagy Csilla, Oroszi Beatrix, Ungvari Zoltan, Adany Roza
Dátum:
2024
ISSN:
2509-2715 2509-2723
Megjegyzések:
The demographic transition poses a significant challenge for health systems, especially in Central and Eastern European (CEE) countries, where the healthcare needs of aging populations are on the rise. This study aimed to describe and compare the health status and utilization of health services among the elderly residing in urban and rural areas of the most deprived region in Hungary. A comprehensive health survey was conducted in 2022, involving a randomly selected sample of 443 older adults (??65 years) in Northeast Hungary. Multivariable logistic regression models adjusting for age, sex, education, financial status, chronic diseases, and activity limitations were used to investigate the association between type of residence and health service use. Among the study participants, 62.3% were female, 38.3% attained primary education, 12.5% reported a bad or very bad financial situation and 52.6% lived in urban areas. Overall, 24% of the elderly rated their health as very good or good (27.8% in urban and 19.7% in rural areas), while 57.8% (52.6% and 63.5% in urban and rural areas) reported limitations in daily activities. Compared to urban residents, rural residents reported lower rates of dentist visits (p?=?0.006), specialist visits (p?=?0.028), faecal occult blood testing (p?<?0.001), colorectal cancer screening with colonoscopy (p?=?0.014), and breast cancer screening (p?=?0.035), and a higher rate of blood pressure measurement (p?=?0.042). Multivariable models indicated that urban residence was positively associated with faecal occult blood testing (OR?=?2.32, p?=?0.014), but negatively associated with blood pressure (OR?=?0.42, p?=?0.017) and blood glucose measurements (OR?=?0.48, p?=?0.009). These findings highlight the influence of residence on health service utilization among older adults in Hungary. Further comprehensive studies are needed to better understand the health needs of the elderly population and to develop policies aimed at promoting healthy aging in CEE countries.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Population ageing
Preventive services
Place of residence
Central and Eastern Europe (CEE)
Older adults
Megjelenés:
GeroScience. - 46 : 2 (2024), p. 2017-2031. -
További szerzők:
Pikó Péter (1987-) (biológus)
Juhász Attila (1970-) (epidemiológus)
Nagy Csilla (1970-) (epidemiológus, népegészségügyi szakember)
Oroszi Beatrix (1970-) (orvos, epidemiológus)
Ungvári Zoltán
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:
GINOP-2.3.2- 15-2016-00005
GINOP
TK2016-78
Egyéb
TKCS-2021/32
Egyéb
135784
OTKA
ÚNKP-22-4-II-DE-268
Egyéb
TKP2021-NKTA-47
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
12.
001-es BibID:
BIBFORM080870
Első szerző:
Kovács Nóra (népegészségügyi szakember)
Cím:
The impact of general practitioners' gender on process indicators in Hungarian primary healthcare: a nation-wide cross-sectional study / Nóra Kovács, Orsolya Varga, Attila Nagy, Anita Pálinkás, Valéria Sipos, László Kőrösi, Róza Ádány, János Sándor
Dátum:
2019
ISSN:
2044-6055
Megjegyzések:
Objectives The objectives of our study were (1) to investigate the association between gender of the general practitioner (GP) and the quality of primary care in Hungary with respect to process indicators for GP performance and (2) to assess the size of the gender impact. Study design A nation-wide cross-sectional study was performed in 2016. Setting and participants The study covered all general medical practices in Hungary (n=4575) responsible for the provision of primary healthcare (PHC) for adults. All GPs in their private practices are solo practitioners. Main outcome measures Multilevel logistic regression models were used to analyse the association between GP gender and process indicators of PHC, and attributable proportion (AP) was calculated. Results 48% of the GPs (n=2213) were women in the study. The crude rates of care provided by female GPs were significantly higher for seven out of eight evaluated indicators than those provided by male GPs. Adjusted for practice, physician and patient factors, GP gender was associated with the haemoglobin A1c (HbA1c) measurement: OR=1.18, 95%CI (1.14 to 1.23); serum creatinine measurement: OR=1.14, 95%CI (1.12 to 1.17); lipid measurement: R=1.14, 95%CI (1.11 to 1.16); eye examination: OR=1.06, 95%CI (1.03 to 1.08); mammography screening: OR=1.05, 95%CI (1.03 to 1.08); management of patients with chronic obstructive pulmonary disease: OR=1.05, 95%CI (1.01 to 1.09) and the composite indicator: OR=1.08, 95%CI (1.07 to 1.1), which summarises the number of care events and size of target populations of each indicator. The AP at the specific indicators varied from 0.97% (95% CI 0.49% to 1.44%) of influenza immunisation to 8.04% (95% CI 7.4% to 8.67%) of eye examinations. Conclusion Female GP gender was an independent predictor of receiving higher quality of care. The actual size of the gender effect on the quality of services seemed to be notable. Factors behind the gender effect should receive more attention in quality improvement particularly in countries where the primary care is organised around solo practices.
Tárgyszavak:
Orvostudományok
Egészségtudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Gender
General practitioner
PRIMARY CARE
Process indicators
Quality of care
Megjelenés:
BMJ Open. - 9 : 9 (2019), p. 1-9. -
További szerzők:
Varga Orsolya (1977-) (orvos, jogász)
Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus)
Pálinkás Anita (1988-) (népegészségügyi szakember)
Sipos Valéria (1988-) (népegészségügyi szakember)
Kőrösi László
Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Sándor János (1966-) (orvos-epidemiológus)
Pályázati támogatás:
Swiss Contribution Programme SH/8/1
Egyéb
GINOP-2.3.2-15-2016-00005
GINOP
EFOP-3.6.3- VEKOP-16-2017-00009
EFOP
Portugal/Hungary Bilateral Project FCT/NKFIH
Egyéb
János Bolyai Scholarship of the Hungarian Academy of Sciences
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
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