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001-es BibID:	BIBFORM126389
035-os BibID:	(WoS)001388876000001 (Scopus)85215863466
Első szerző:	Király József
Cím:	Breaking the guidelines : how financial unawareness fuels guideline deviations and inefficient DVT diagnostics / Kiraly Jozsef, Berzi Andras, El-Kareh Robert, Sebestyen Eniko, Ujvarosy Dora, Emri Miklos, Bhattoa Harjit Pal, Kappelmayer Janos, Miller Kristen E., Toth Gabor
Dátum:	2025
ISSN:	2194-8011 2194-802X
Megjegyzések:	Objectives: To examine factors impacting diagnostic evaluation of suspected deep vein thrombosis (DVT) by analyzing the test ordering patterns and provider decision- making within a universal health coverage system in Hungary. Methods: We analyzed test orders for suspected DVT between 2007 and 2020, and the financial framework influencing diagnostic practices. An anonymous survey was also conducted among Emergency Department physicians to explore factors influencing diagnostic decision-making. Results: Atotalof6,821patientswereidentified.From2008 to 2013, the most common diagnostic approach combined D-dimer and duplex ultrasound tests (64.5 %), followed by sole ultrasound (20.5 %) and sole D-dimer (15 %) testing. A marked shift occurred from 2014 onward, with sole ultra- sound rising to 88 % of cases by 2018?2020, while combined testing and sole D-dimer orders decreased to 7.9 and 4 %, respectively. In survey results, time efficiency emerged as a key factor for bypassing D-dimer testing, cited by 75 % of physicians. 45 % believed D-dimer costs were comparable to or higher than duplex ultrasound. Financial analysis revealed that the outdated performance points system misrepresented actual costs, resulting in duplex ultrasound being significantly underfunded, which impacts the Radi- ology Department. This discrepancy contributes to higher national level expenses, driven by the increased reliance on ultrasound. Conclusions: We found diagnostic practices deviating from international diagnostic guidelines, with an increase in duplex ultrasound over D-dimer. This shift, allowed by an outdated financing structure, increases overall costs for the healthcare system. Revising financial frameworks to reflect true costs is essential for sustainable operations in universal health coverage systems.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok beszámoló folyóiratcikk diagnostics efficiency healthcare cost decision-making
Megjelenés:	Diagnosis. - 12 : 2 (2025), p. 232-240. -
További szerzők:	Berzi András El-Kareh, Robert Sebestyén Enikő (1995-) (onkológus) Ujvárosy Dóra (1985-) Emri Miklós (1962-) (fizikus) Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Kappelmayer János (1960-) (laboratóriumi szakorvos) Miller, Kristen E. Tóth Gábor (1983-) (labororvos)
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001-es BibID:	BIBFORM134193
035-os BibID:	(scopus)105024456285 (wos)001636258300001
Első szerző:	Rácz Szilvia (molekulársi biológus)
Cím:	Exploring Vitamin D Trends Through Big Data Analysis / Szilvia Racz, Miklos Emri, Ervin Berenyi, Laszlo Horvath, Bela E. Toth, Sandor Barath, Edit Kalina, Luca Jozsa, Amrit Pal Bhattoa-Buzas, William B. Grant, Harjit Pal Bhattoa
Dátum:	2025
ISSN:	2072-6643
Megjegyzések:	Background/Objectives: Big data analysis has revolutionized medical research, making it possible to analyze vast amounts of data and gain valuable insights that were previously impossible to obtain. Our knowledge of the characteristics of vitamin D sufficiency is primarily based on data from a limited number of observations, generally spanning a few years at most. Methods: Here at the Medical Faculty of the University of Debrecen, the big data approach has allowed us to analyze trends in vitamin D status using nearly 60,000 25-hydroxyvitamin D (25(OH)D) concentration results from 2000 onwards. Results: Apart from analyzing the well-known phenomenon of seasonality in 25(OH)D concentration, we observed a trend in test requests, which increased from a few hundred in 2000 to almost 10,000 in 2020. Of particular interest is the change in the gender gap in test requests. In previous years, test requests were primarily from women, but by the end of the analysis period, a significant number of requests were from men as well. Since the data set includes all age groups, we analyzed 25(OH)D concentration for incremental age sets of five years, from a few months to 100 years old. The prevalence of vitamin D insufficiency (<75 nmol/L) was clearly demarcated among various years of observation, age groups, sexes, and seasons. Our data was particularly valuable for analyzing the effect of the methodology used for 25(OH)D determination. Three different methodologies were used during the study period, and clear, statistically significant bias was observed. Conclusions: Our results clearly demonstrate the effect of the methodology used to determine 25(OH)D concentrations on vitamin D status, explicitly highlighting the urgent need to standardize the various platforms used to measure this important analyte and its consequences for public health.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk 25-hydroxyvitamin D big data methodology seasonal variations age gender vitamin D
Megjelenés:	Nutrients. - 17 (2025), p. 1-16. -
További szerzők:	Emri Miklós (1962-) (fizikus) Berényi Ervin (1964-) (radiológus) Horváth László (1973-) (gyógyszerész) Tóth E. Béla (1960-) (orvos) Baráth Sándor (1977-) (biológus) Kalina Edit (1971-) (laboratóriumi analitikus) Józsa Luca Bhattoa-Buzas, Amrit Pal Grant, William B. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos)
Pályázati támogatás:	TKP2021-NKTA-34 Egyéb
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001-es BibID:	BIBFORM113487
035-os BibID:	(scopus)85164204449
Első szerző:	Rácz Szilvia (molekulársi biológus)
Cím:	Laboratóriumi paraméterek kódolása a LOINC-rendszer szerint a Debreceni Egyetem Klinikai Központjában / Rácz Szilvia, Emri Miklós, Opposits Gábor, Berényi Ervin, Benczik Lajos, Ludman István Attila, Kappelmayer János, Bhattoa Harjit Pal
Dátum:	2023
ISSN:	0030-6002 1788-6120
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban folyóiratcikk
Megjelenés:	Orvosi Hetilap. - 164 : 27 (2023), p. 1043-1051. -
További szerzők:	Emri Miklós (1962-) (fizikus) Opposits Gábor (1974-) (fizikus, szoftver fejlesztő) Berényi Ervin (1964-) (radiológus) Benczik Lajos Ludman István Attila Kappelmayer János (1960-) (laboratóriumi szakorvos) Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos)
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