Találati lista | Tudóstér

001-es BibID:	BIBFORM124937
035-os BibID:	(Scopus)85203113251 (WoS)001325576500004
Első szerző:	Erdei Csilla
Cím:	Oral Mucosal Human Papillomavirus and Epstein-Bar Virus Rates in Patients with Dry Mouth and/or Sjögren`s Syndrome in a Hungarian Cohort / Csilla Erdei, Ágnes Heizer, Károly Mensch, Krisztina Szarka, Emese Virág Kiss, Krisztina Márton
Dátum:	2024
ISSN:	1757-9996 1602-1622
Megjegyzések:	Purpose: To find an association between oral mucosal human papilloma- and/or Epstein-Barr (HPV, EBV) virus infection in patients with dry mouth and/or Sjögren's syndrome (SS) compared to healthy controls and to find connections with salivary gland histopathological alterations. Materials and methods: Ninety-two participants were divided into four groups: 1. healthy controls (n = 32); 2. xerostomia (n = 28); 3. hyposalivation (n = 22); and 4. SS groups (n = 10). To detect virus infection brush biopsy was outlined in all groups. Detections of virus-specific sequences were achieved with polymerase chain reaction (PCR). Lip biopsy and histopathological assessment was performed in groups 2, 3 and 4. Results: HPV positivity of oral mucosal cells was shown in group 1: 1 (3.12%); group 2: 3 (10.7%); group 3: 2 (8.26%); and in group 4: 0 of the samples. EBV was present in group 1: 14 (43.7%); group 2: 17 (60.7%); group 3: 6 (27.3%); and in group 4: 5 (50%) of the cases. There was no statistically significant difference between the attributes. Intact salivary gland in 28.2%, chronic sialadenitis in 28.2%, stromal fibrosis in 6.5%, lipomatous atrophy in 8.6%, fibrous atrophy in 6.5% and positive focus score (SS) in 26.1% were found in the subjects. Neither HPV nor EBV infection caused statistically significantly more histological abnormalities. Conclusion: Orofacial mucosal HPV and/or EBV DNA rates did not differ statistically significantly in patients with xerostomia or hyposalivation or SS compared to healthy controls, therefore, it cannot prove the provocative role of these viruses in dry mouth and/or SS. Neither dry mouth nor SS were accompanied by statistically significantly more salivary gland alterations in HPV- and/or EBV-positive subjects; these alterations are frequent in the virus-negative cases too.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Epstein-Barr virus Sjögren's syndrome dry mouth human papillomavirus oral mucosa
Megjelenés:	Oral Health and Preventive Dentistry. - 22 : 1 (2024), p. 443-452. -
További szerzők:	Heizer Ágnes Mensch Károly Szarka Krisztina (1971-) (molekuláris biológus, mikrobiológus) Kiss Emese Virág Márton Krisztina
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM077798
Első szerző:	Mensch Károly
Cím:	PCR Technique Assisting the Early Diagnosis of Human Papillomavirus : a retrospective clinical study / Karoly Mensch, Krisztina Szarka, Henrik Mensch, Adrienn Dobai, Zoltan Magyar, Mariana Pacurar, Aurel Claudiu Vartolomei, Daniela Manuc, Csaba Dobo Nagy
Dátum:	2018
Megjegyzések:	The number of oral cancers associated with Human Papillomavirus (HPV) infection is increasing worldwide.The purpose of this retrospective clinical trial is to investigate the relationship between genital and oral HPVinfection and to observe the possibilities of polymerase chain reaction (PCR) technique and the limitationsfor oral HPV infection. The results of genital and oral HPV screening of 34 female patients and their partner,and 14 single female patients were processed in a private practice in Budapest between 2012 and 2015.After brush-biopsy sampling, HPV DNA identification and typing were performed using PCR technique. All inall 164 samples were typed. HPV DNA was detected in 76 cases (48.20%). HPV was detected in 55 casesfrom the genital samples (67%), and in 21 cases from the oral samples (25.6%). Genital HPV infection wasstatistically significantly higher in women (79.2% vs 22,9%, p<0.001). Gender comparison of genital HPVinfection showed a statistically significant difference (79.2% for women, 50% for men, p = 0.006). In caseof genital HPV infection, the oral HPV infection of the same person is more frequent. In this study, the abovementioned difference is significant for women and not significant for men. HPV16 is the HPV genotypewhich was identified in the highest ratio(47.2%). PCR technique is capable of the detection of oral HPVinfection, but follow-up studies with higher case number , and questionnaire studies are needed to understandHPV transmission more accurately.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Revista De Chimie. - 69 : 10 (2018), p. 2781-2787. -
További szerzők:	Szarka Krisztina (1971-) (molekuláris biológus, mikrobiológus) Mensch Henrik Dobai Adrienn Magyar Zoltán Pacurar, Mariana Vartolomei, Aurel Claudiu Manuc, Daniela Dobó Nagy Csaba (1961-) (fogszakorvos)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: