Találati lista | Tudóstér

001-es BibID:	BIBFORM126432
035-os BibID:	(WoS)001077004600002 (Scopus)85181761016
Első szerző:	Li, Ying
Cím:	Examining the environmental risk factors of progressive-onset and relapsing-onset multiple sclerosis : recruitment challenges, potential bias, and statistical strategies / Li Y., Saul A., Taylor B., Ponsonby A. L., Simpson-Yap S., Blizzard L., Broadley S., Lechner-Scott J., Ausimmune/AusLong Investigators Group, Karabudak R., Patti F., Eichau S., Onofrj M., Ozakbas S., Horakova D., Kubala Havrdova E., Grand'Maison F., Alroughani R., Gerlach O., Amato M. P., Altintas A., Girard M., Duquette P., Blanco Y., Ramo-Tello C., Laureys G., Kalincik T., Khoury S. J., Shaygannejad V., Etemadifar M., Singhal B., Mrabet S., Foschi M., Habek M., John N., Hughes S., McCombe P., Ampapa R., van der Walt A., Butzkueven H., de Gans K., McGuigan C., Oreja-Guevara C., Sa M. J., Petersen T., Al-Harbi T., Sempere A. P., Van Wijmeersch B., Grigoriadis N., Prevost J., Gray O., Castillo-Trivino T., Macdonell R., Lugaresi A., Sajedi S. A., MSBase, van der Mei I.
Dátum:	2024
ISSN:	0340-5354
Megjegyzések:	It is unknown whether the currently known risk factors of multiple sclerosis reflect the etiology of progressive-onset multiple sclerosis (POMS) as observational studies rarely included analysis by type of onset. We designed a case-control study to examine associations between environmental factors and POMS and compared effect sizes to relapse-onset MS (ROMS), which will offer insights into the etiology of POMS and potentially contribute to prevention and intervention practice. This study utilizes data from the Primary Progressive Multiple Sclerosis (PPMS) Study and the Australian Multi-center Study of Environment and Immune Function (the AusImmune Study). This report outlines the conduct of the PPMS Study, whether the POMS sample is representative, and the planned analysis methods. The study includes 155 POMS, 204 ROMS, and 558 controls. The distributions of the POMS were largely similar to Australian POMS patients in the MSBase Study, with 54.8% female, 85.8% POMS born before 1970, mean age of onset of 41.44 ? 8.38 years old, and 67.1% living between 28.9 and 39.4? S. The POMS were representative of the Australian POMS population. There are some differences between POMS and ROMS/controls (mean age at interview: POMS 55 years vs. controls 40 years; sex: POMS 53% female vs. controls 78% female; location of residence: 14.3% of POMS at a latitude ? 28.9?S vs. 32.8% in controls), which will be taken into account in the analysis. We discuss the methodological issues considered in the study design, including prevalence-incidence bias, cohort effects, interview bias and recall bias, and present strategies to account for it. Associations between exposures of interest and POMS/ROMS will be presented in subsequent publications.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Bias Case-control Environmental factors Progressive-onset multiple sclerosis Subject recruitment.
Megjelenés:	Journal Of Neurology. - 271 : 1 (2024), p. 472-485. -
További szerzők:	Saul, Alice Taylor, Bruce V. Ponsonby, Anne-Louise Simpson-Yap, Steve Blizzard, Leigh Broadley, Simon Lechner-Scott, Jeannette Karabudak, Rana Patti, Francesco Eichau, Sara Onofrj, Marco Ozakbas, Serkan Horakova, Dana Kubala Havrdova, Eva Grand'Maison, Francois Alroughani, Raed Gerlach, Oliver Amato, Maria Pia Altintas, Ayse Girard, Marc Duquette, Pierre Blanco, Yolanda Ramo-Tello, Cristina Laureys, Guy Kalincik, Tomas Khoury, Samia J. Shaygannejad, Vahid Etemadifar, Masoud Singhal, Bhim Mrabet, Saloua Foschi, Matteo Habek, Mario John, Nevin Hughes, Stella McCombe, Pamela Ampapa, Radek Walt, Anneke van der Butzkueven, Helmut de Gans, Koen McGuigan, Christopher Oreja-Guevara, Celia Sá, Maria José Petersen, Thor Al-Harbi, Talal Sempere, Perez A. Wijmeersch, Bart Van Grigoriadis, Nikolaos Prevost, Julie Gray, Orla Castillo Triviño, Tamara Macdonell, Richard Lugaresi, Alessandra Sajedi, Seyed Aidin Mei, Ingrid van der Csépány Tünde (1956-) (neurológus, pszichiáter) Ausimmune/AusLong Investigators Group MSBase Study Group
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM135464
035-os BibID:	(Scopus)105029267510 (WoS)001679383200001
Első szerző:	Souissi, Amira
Cím:	Effect of late-onset on multiple sclerosis phenotype and outcome : evidence from a multi-national registry / Amira Souissi, Francesco Patti, Tim Spelman, Clara Chisari, Amina Gargouri, Nevin John, Allan G. Kermode, Tomas Kalincik, Helmut Butzkueven, Seyed Aidin Sajedi, Jeannette Lechner?Scott, Izanne Roos, Guy Laureys, Bruce Taylor, Raed Alroughani, Samia J. Khoury, Richard Macdonell, Bianca Weinstock?Guttman, Eva Kubala Havrdova, Davide Maimone, Stephen Reddel, Marzena Fabis?Pedrini, Barbara Willekens, Abdorreza Naser Moghadasi, Patrice Lalive, Alessandra Lugaresi, Serkan Ozakbas, Claudio Solaro, Simón Cárdenas?Robledo, Vahid Shaygannejad, Masoud Etemadifar, Cavit Boz, Sara Eichau, Valentina Tomassini, Murat Terzi, Alexandre Prat45 · Mario Habek46 · Yolanda Blanco47 · Ayse Altintas48 · Oliver Gerlach49,50 · Recai Turkoglu51 · Katherine Buzzard52 · Olga Skibina53,54,55 · Aysun Soysal56 · Anneke van der Walt, Stella Hughes, Vincent van Pesch, Matteo Foschi, Andrea Surcinelli, Julie Prevost, Cristina Ramo?Tello, Chris McGuigan, Maria Jose Sa, Jens Kuhle, Daniele Spitaleri, Bhim Singhal, Radek Ampapa, Koen de Gans, Thor Petersen, Mihaela Simu, Emmanuelle Lapointe, Jose Luis Sanchez?Menoyo, Orla Gray, Justin Garber, Eduardo Aguera?Morales, Katrin Gross?Paju, Tamara Castillo?Triviño, Abdullah Al?Asmi, Nikolaos Grigoriadis, Jihad Inshasi, Talal Al?Harbi, Todd A. Hardy, Sudarshini Ramanathan, Melissa Cambron, Neil Shuey, Angel Perez sempere, Tunde Csepany, Irene Treviño?Frenk, Csilla Rozsa, Marija Cauchi, Rana Karabudak, Saloua Mrabet, Riadh Gouider
Dátum:	2026
ISSN:	0340-5354
Megjegyzések:	Background Multiple Sclerosis (MS) severity is influenced by several factors. Understanding the impact of age at disease onset may help to better characterize clinical and disease features across age groups. This study aimed to characterize the clinical features and disability outcomes of late-onset MS (LOMS) and very late-onset MS (vLOMS), compared to adultonset MS (AOMS). Methods We conducted an observational study using data from the MSBase registry and categorized patients based on age at MS onset: AOMS (18?39 years), transition onset (40?49 years), LOMS (50?59 years), and vLOMS (?60 years). Disease progression was assessed using the 24 week confirmed disability progression, EDSS4 and 6 milestones, conversion to secondary progressive MS(SPMS), and the first progression independent of relapse activity (PIRA) event. Cox proportional hazard regression models were used to determine unadjusted hazard ratios(HR), and propensity score inverse probability of treatment weighting(PS-IPTW) balanced covariate distributions. Results Among 81,236 patients, 5.2% had LOMS and 1% had vLOMS. Primary progressive MS was more frequent in LOMS and vLOMS (21.7 and 24%, respectively). Patients with LOMS and vLOMS had a significantly increased risk of 24 week confirmed disability progression (HR:LOMS=1.39, vLOMS=1.80), EDSS 4 (HR:LOMS=2.14, vLOMS=2.95), EDSS 6 (HR:LOMS=2.33, vLOMS=6.33), SPMS (HR:LOMS=1.62, vLOMS=2.38), and first PIRA event (HR:LOMS=2.12, vLOMS=2.93). Conclusion LOMS and vLOMS exhibited a more progressive disease onset and higher disability milestones compared with AOMS.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Multiple Sclerosis Prognosis Aging Progression Immunosenescence
Megjelenés:	Journal Of Neurology. - 273 : 2 (2026), p. 1-15. -
További szerzők:	Patti, Francesco Spelman, Tim Chisari, Clara Gargouri, Amina John, Nevin Kermode, Allan G. Kalincik, Tomas Butzkueven, Helmut Sajedi, Seyed Aidin Lechner-Scott, Jeannette Roos, Izanne Laureys, Guy Taylor, Bruce V. Alroughani, Raed Khoury, Samia J. Macdonell, Richard Weinstock-Guttman, Bianca Havrdova, Eva Maimone, Davide Reddel, Stephen Fabis-Pedrini, Marzena Willekens, Barbara Moghadasi, Abdorreza Naser Lalive, Patrice H. Lugaresi, Alessandra Ozakbas, Serkan Solaro, Claudio Cárdenas-Robledo, Simón Shaygannejad, Vahid Etemadifar, Masoud Boz, Cavit Eichau, Sara Tomassini, Valentina Terzi, Murat Prat, Alexandre Habek, Mario Blanco, Yolanda Altintas, Ayse Gerlach, Oliver Turkoglu, Recai Buzzard, Katherine Skibina, Olga Soysal, Aysun Walt, Anneke van der Hughes, Stella Pesch, Vincent van Foschi, Matteo Surcinelli, Andrea Prevost, Julie Ramo-Tello, Cristina McGuigan, Christopher Sa, Maria Jose Kuhle, Jens Spitaleri, Daniele Singhal, Bhim Ampapa, Radek Gans, Koen de Petersen, Thor Simu, Mihaela Lapointe, Emmanuelle Sanchez-Menoyo, Jose Gray, Orla Garber, Justin Aguera-Morales, Eduardo Gross-Paju, Katrin Castillo Triviño, Tamara Al-Asmi, Abdullah Grigoriadis, Nikolaos Inshasi, Jihad Al-Harbi, Talal Hardy, Todd A. Ramanathan, Sudarshini Cambron, Melissa Shuey, Neil Sempere, Perez A. Csépány Tünde (1956-) (neurológus, pszichiáter) Trevino-Frenk, Irene Rózsa Csilla Cauchi, Marija Karabudak, Rana Mrabet, Saloua Gouider, Riadh
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM083268
Első szerző:	Zhou, Yuan
Cím:	Redefining the Multiple Sclerosis Severity Score (MSSS) : the effect of sex and onset phenotype / Yuan Zhou, Suzi B. Claflin, Jim Stankovich, Ingrid van der Mei, Steve Simpson, Richard H. Roxburgh, Tomas Kalincik, Leigh Blizzard, Alessandra Lugaresi, Raed Alroughani, Seyed Aidin Sajedi, Helmut Butzkueven, Eugenio Pucci, Daniele L. A. Spitaleri, Franco Granella, Edgardo Cristiano, Bassem Yamout, Stella Hughes, Riadh Gouider, José Luis Sánchez Menoyo, Javier Olascoaga, Chris McGuigan, Cameron Shaw, Allan G. Kermode, Krisztian Kasa, Talal Al-Harbi, Ayse Altintas, Guy Laureys, Yara Fragoso, Todd A. Hardy, Tunde Csepany, Carmen-Adella Sirbu, Danny Decoo, Attila Sas, Jose C. Alvarez-Cermeño, Karim Kotkata, Jorge Millán-Pascual, Bruce V. Taylor
Dátum:	2020
ISSN:	1352-4585
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Multiple Sclerosis. - 26 : 13 (2020), p. 1765-1774. -
További szerzők:	Claflin, Suzi B. Stankovich, Jim Mei, Ingrid van der Simpson, Steve Roxburgh, Richard H. Kalincik, Tomas Blizzard, Leigh Lugaresi, Alessandra Alroughani, Raed Sajedi, Seyed Aidin Butzkueven, Helmut Pucci, Eugenio Spitaleri, Daniele L. A. Granella, Franco Cristiano, Edgardo Yamout, Bassem Hughes, Stella Gouider, Riadh Sánchez Menoyo, José Luis Olascoaga, Javier McGuigan, Christopher Shaw, Cameron Kermode, Allan G. Kása Krisztián Al-Harbi, Talal Altintas, Ayse Laureys, Guy Fragoso, Yara Hardy, Todd A. Csépány Tünde (1956-) (neurológus, pszichiáter) Sirbu, Carmen-Adella Decoo, Danny Sas Attila Alvarez-Cermeño, Jose C. Kotkata, Karim Millán-Pascual, Jorge Taylor, Bruce V.
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: