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001-es BibID:	BIBFORM120170
Első szerző:	Paragh György (belgyógyász)
Cím:	Milyen volt a hyperlipidaemia kezelése és a kezelőorvosok attitűdje 2022-ben? / Paragh György, Harangi Mariann, Bársony Gábor, Mazzag Bálint, Együd Ferenc
Dátum:	2024
ISSN:	1589-7311
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban folyóiratcikk
Megjelenés:	Metabolizmus. - 22 : 1 (2024), p. 26-32. -
További szerzők:	Harangi Mariann (1974-) (belgyógyász, endokrinológus) Bársony Gábor Mazzag Bálint Együd Ferenc
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM131753
035-os BibID:	(scopus)105011733402 (wos)001536797900001
Első szerző:	Reiber István
Cím:	Goal Achievement in 3017 Patients at Very High Cardiovascular Risk Based on Different LDL Cholesterol Calculations and Non-HDL Cholesterol Levels : Shortcomings of the Use of Non-HDL Cholesterol as a Target Depending on Triglyceride Levels / Reiber István, Márk László, Lőrincz Hajnalka, Együd Ferenc, Mező Izabella, Paragh György
Dátum:	2025
ISSN:	2077-0383
Megjegyzések:	Objectives: The goal of this study was to investigate lipid goal achievement rates in very high-risk patients over six months using high-intensity rosuvastatin or rosuvastatin/ezetimibe combination lipid-lowering therapy. Methods: This prospective, observational study was conducted on the patients of 150 general and 60 specialist practices. Our analysis included 3017 patients (47% women) who completed six months of therapy. Of these, 55.5% had pre-existing cardiovascular disease, 35.6% had cerebrovascular disease, and 20.4% had peripheral vascular disease. Results: At six months, in patients receiving rosuvastatin monotherapy (20.5%), the 1.8 LDL-C achievement rate was 37%; in those taking the fix rosuvastatin/ezetimibe combination (63.7%), it was 52%, and the 1.4 level attainment proved to be 11% and 22%, respectively. The rates of LDL-C reduction of at least 50% were 32% and 42%, respectively. Overall, non-HDL-C goal achievement rates were higher than when LDL-C was calculated using the Martin?Hopkins or Sampson methods but similar to those calculated with the Friedewald formula. When patients were stratified by triglyceride quartiles, non-HDL-C goal achievement rates were significantly higher (p < 0.001) in cases with triglyceride levels below 1.2 mmol/L. Conversely, Friedewald-calculated LDL-C (F-LDL-C) goal achievement rates were significantly higher (p < 0.001) in patients with triglyceride levels above 1.7 mmol/L. Conclusions: Our findings suggest that the consistent use of fixed high-intensity statin and ezetimibe combinations can improve lipid goal achievement. However, comparing the achievement of LDL-C goals (calculated by three methods) and non-HDL-C goals also confirmed that the common practice of automatically adding 0.8 mmol/L to the calculated LDL-C value to determine non-HDL-C leads to inaccuracies, particularly in the lower triglyceride ranges.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk rosuvastatin statin-ezetimibe combination LDL cholesterol non-HDL cholesterol target values
Megjelenés:	Journal of Clinical Medicine. - 14 : 14 (2025), p. 1-12. -
További szerzők:	Márk László (1956-) (belgyógyász, kardiológus) Lőrincz Hajnalka (1986-) (biológus) Együd Ferenc Mező Izabella Paragh György (1953-) (belgyógyász)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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