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001-es BibID:	BIBFORM003512
Első szerző:	Lőcsey Lajos (belgyógyász, nephrológus)
Cím:	Importance of obesity in chronic renal failure - visceral obesity and cardiovascular complications / Lajos Lőcsey, Béla Borbás, Beatrix Szlanka, István Ménes, Anikó Dán, László Szabó, László Asztalos, István Lőrincz
Dátum:	2008
Megjegyzések:	After renal transplantation significant increased BM1, FM. In chronic dialysed program me increased the aging, accelerating atherosclerosis and malnourished complications. Aims of study: relationship between change of body different compartment (fat and water) and cardiovascular complications (blood and pulse pressure, cardiac events, arterial stiffness). We are investigated dialysed pts 79 males, 56 females (67,12+-7,26 years) and renal transplanted 81 males, 64 females (45,51+-11,27 years). Blood pressure and cardiac events measured with CardioTens(Meditech 04), arterial stiffness with arteriograph (TensioClinic-TensioMed). Bioimpedancia analysis (B1A) was performed with multifrequential B1A analyser (InBody 720). We compared the LAP-lipid accumulation product-waist (cm) x serum triglyceride (mM/l) and waist/hip ratio in malnourished, and obes pts in dialysis programme and after renal transplantation. After transplantation cystatin C, homocysteine concentrations were 2,1 vs 5,2mg/l and 15,21 vs. 23,78 umol/l. Dialysed pts have hypertriglyceridaemia, in transplanted pts were high hypercholesterinaemia, LDL and ApoB levels. In dialysis programme was 9,87% malnourished pts, with decreased FM (4,9-12,6 kg),visceral fat surface area less -26,9+-12,8cm2 than normal. In obes dialysed pts were 29,87%, increased FM (16,89+-6,71 kg), and VFA (79,25-178,26 cm2). Transplanted pts increased BMI, in 63,14 % FM, VFA (85,6-197,25 cm2). LAP was 72,22+-13,74 cm x mM/l (<21kg/m2 BM1), and 227,15+-41,78 cm x mM/l (BMI>30 kg/m2). In obes pts was frequently aritmia, non dipper hypertension and negative diurnal index, and pulse pressure increased higher (>70 mmHg) in 38 % of dialysis pts, and 24 % of transplanted pts. The augmentations index (AIx) increased in dialysed female 60 %, after transplantation only 18 % (>10 %). The pulse wave velocity (PWV) was higher in dialysed males 25 %, after transplantation 10 % (>12m/s). Conclusions: In obes pts increased significantly BM1, FM and VFA, with increased LAP and waist/hip ratio, increased blood and pulse pressure, associated arterial stiffness with cardiac events (angina pectoris, arrhythmia).
Tárgyszavak:	Orvostudományok Klinikai orvostudományok előadáskivonat könyvrészlet
Megjelenés:	XXII. International Congress of The Transplantation Society 10-14 August, 2008, Sydney, Australia. - 495 00 : 1515 (2008), p. 495 00.
További szerzők:	Borbás Béla Szlanka Beatrix Ménes István Dán Anikó Lőrincz István (1950-) (belgyógyász, kardiológus) Asztalos László (1951-) (sebész) Szabó László (1975-) (sebész)
Internet cím:	elektronikus változat
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