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001-es BibID:	BIBFORM007125
Első szerző:	Szekanecz Zoltán (reumatológus, belgyógyász, immunológus)
Cím:	Cytokines in rheumatoid arthritis : potential targets for pharmacological intervention / Szekanecz, Z., Koch, A. E., Kunkel, S. L., Strieter, R. M.
Dátum:	1998
ISSN:	1170-229X (Print)
Megjegyzések:	The ingress of inflammatory leucocytes into the synovium is a crucial step in the pathogenesis of rheumatoid arthritis (RA). Cytokines are mediators involved in the inflammatory events, adhesive mechanisms, angiogenesis and osteopenia associated with RA. Pro- and anti-inflammatory cytokines, growth factors and chemokines all have an important role in these processes. Because the efficacy of currently used antirheumatic therapy is often limited, there is a need for more specific intervention strategies. Anticytokine therapy may include the use of monoclonal antibodies, antagonistic cytokines, soluble cytokine receptors, cytokine receptor antagonists, somatic gene transfer or other approaches. Hopefully, the study of cytokines and their interactions will lead to the development of new immunomodulatory strategies that will benefit patients with RA.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Animals Arthritis, Rheumatoid Cytokines Humans
Megjelenés:	Drugs and Aging. - 12 : 5 (1998), p. 377-390. -
További szerzők:	Koch, Alisa E. Kunkel, Steven L. Strieter, Robert M.
Internet cím:	elektronikus változat
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