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001-es BibID:	BIBFORM015603
035-os BibID:	16144643
Első szerző:	Matesz Klára (anatómus, neurobiológus)
Cím:	Extracellular matrix molecules and their possible roles in the regeneration offrog nervous system / Clara Matesz, Laszlo Modis, Gabor Halasi, Zsuzsa M. Szigeti, Szabolcs Felszeghy, Timea Bacskai, Gyorgy Szekely
Dátum:	2005
ISSN:	0361-9230 (Linking)
Megjegyzések:	Recent biochemical and histochemical analyses explored different components ofthe extracellular matrix (ECM) in the nervous system, and either permissive ornon-permissive roles in neuronal development and regeneration were suggested. Theaim of this study was to detect the distribution pattern of a few of thesemolecules in the nervous system of intact frogs and during nerve regeneration.The hyaluronan (HA) and tenascin C reactions were negative in the peripheralnerves, but appeared in their entry zones. In the CNS, different populations ofneurons were surrounded with HA and tenascin C-positive material, forming aperineuronal net (PN). The phosphacan reaction was weakly positive in the PNS,and a moderate intensity was detected in the entry zone and in the PN. Lamininand fibronectin immunoreactivity was strong in the PNS, but laminin could not bedetected in the CNS. In animals with cut and regenerating vestibulocochlearnerve, the distribution of the ECM molecules in the CNS and PNScharacteristically changed from that of the normal pattern. Our results showed anon-homogenous distribution of ECM components in the frog nervous system thatcould be associated with their different roles in physiological and pathologicalprocesses.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban 0 (Fibronectins) 0 (Laminin) 0 (Tenascin) 9004-61-9 (Hyaluronic Acid) Animals Axotomy/methods Extracellular Matrix/physiology Fibronectins/metabolism Hyaluronic Acid/metabolism Immunohistochemistry/methods Laminin/metabolism Nerve Regeneration/physiology Nervous System/cytology/*metabolism Neurons/metabolism Rana esculenta Tenascin/metabolism Time Factors egyetemen (Magyarországon) készült közlemény Vestibulocochlear Nerve/injuries/physiology
Megjelenés:	Brain research bulletin. - 66 : 4-6 (2005), p. 526-531. -
További szerzők:	Módis László (1939-) (anatómus, kötőszövetbiológus) Halasi Gábor (1976-) (neurobiológus) Máthéné Szigeti Zsuzsa (1976-) (biológus-ökológus) Felszeghy Szabolcs Béla (1972-) (fogorvos, anatómus, kötőszövetbiológus) Bácskai Tímea (1974-) (biológus, neurobiológus) Székely György (1926-2017) (neurobiológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat elektronikus változat DOI
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