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001-es BibID:	BIBFORM015914
035-os BibID:	PMID 20036936 PMC2917905
Első szerző:	Szekanecz Zoltán (reumatológus, belgyógyász, immunológus)
Cím:	Chemokines and chemokine receptors in arthritis / Szekanecz, Z., Vegvari, A., Szabo, Z., Koch, A. E.
Dátum:	2010
ISSN:	1945-0524 (Electronic)
Megjegyzések:	Chemokines are involved in leukocyte recruitment to inflammatory sites, such as the synovial tissue in rheumatoid arthritis (RA). There is a structural and a functional classification of chemokines. The former includes four groups: CXC, CC, C and CX3C chemokines. Chemokines may also be either inflammatory or homeostatic, however, these functions often overlap. Anti-chemokine and anti-chemokine receptor targeting may be therapeutically used in the future biological therapy of arthritis. Most data in this field have been obtained from animal models of arthritis as only very few human RA trials have been completed. However, it is very likely that various specific chemokine and chemokine receptor antagonists will be developed and administered to RA patients.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Arthritis, Rheumatoid/drug therapy/immunology Chemokines/classification/immunology Drug Delivery Systems Gene Expression Regulation/immunology Humans Immunotherapy/methods Neovascularization, Physiologic/immunology Receptors, Chemokine/immunology Synovitis/*immunology
Megjelenés:	Frontiers in Bioscience (Scholar edition). - 2 (2010), p. 153-167. -
További szerzők:	Végvári Anikó (belgyógyász, III. sz. Belgyógyászati Klinika) Szabó Zoltán (1970-) (belgyógyász, reumatológus) Koch, Alisa E.
Internet cím:	elektronikus változat Intézményi repozitóriumban (DEA) tárolt változat
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