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001-es BibID:	BIBFORM017049
Első szerző:	Barta Zsolt (belgyógyász, gasztroenterológus)
Cím:	Celiac disease and microscopic colitis : a report of 4 cases / Barta Zsolt, Zold Eva, Nagy Arpad, Zeher Margit, Csipo Istvan
Dátum:	2011
ISSN:	1007-9327
Megjegyzések:	Celiac disease (CD) is an autoimmune disorder of the small intestine that occurs in genetically predisposed people at all ages. However, it can be associated also to other immunopathological disorders, and may be associated with abnormal histology in segments of the gut other than the small bowel including colonic inflammation. While guidelines for endoscopic investigation of the jejunum are well defined, no indication is defined for colonic investigation. We describe four cases of concurrent CD and microscopic colitis (MC) diagnosed at our department over a 10-year period and analyzed the main features and outcomes of CD in this setting. The symptoms of these patients were improved initially by a gluten-free diet before the onset of MC symptoms. Two of the patients were siblings and had an atypical form of CD. The other two patients with CD and MC also presented with fibrosing alveolitis and were anti-Saccharomyces cerevisiae antibody positive. The co-existence of immune-mediated small bowel and colonic inflammatory and pulmonary diseases are not well-known, and no systematic approach has been used to identify the lifelong patterns of these immune-based diseases. Patients can develop, or present with CD at any stage in life, which can co-exist with other gastrointestinal diseases of (auto-) immune origin. In addition, the familial co-existence and prevalence of MC in patients with a prior diagnosis of CD are unclear. Clinicians managing celiac disease should be aware of these associations and understand when to consider colon investigation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Collagen colitis Lymphocytic colitis Celiac disease Fibrosing alveolitis Anti-saccharomyces cerevisiae antibody
Megjelenés:	World Journal of Gastroenterology. - 17 : 16 (2011), p. 2150-2154. -
További szerzők:	Zöld Éva (1978-) (belgyógyász) Nagy Árpád (1980-) (belgyógyász, háziorvos) Zeher Margit (1957-2018) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Csípő István (1953-) (vegyész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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