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001-es BibID:	BIBFORM017952
Első szerző:	Barta Kitti (belgyógyász)
Cím:	The effect of sleep apnea on QT interval, QT dispersion, and arrhythmias / Barta K., Szabó Z., Kun C., Munkácsy C., Bene O., Tünde Magyar M., Csiba L., Lörincz I.
Dátum:	2010
Megjegyzések:	QT interval (QT) and QT dispersion (QTd) are electrocardiograph (ECG) parameters for theevaluation of myocardial repolarization. The inhomogeneity of ventricular repolarization is associatedwith ventricular arrhythmias. An increased QT, QTd, and increased incidence of nocturnal cardiac rhythmdisturbances have been described in patients with obstructive sleep apnea (OSA), while other investigatorsdid not find a relationship between ventricular arrhythmias and OSA.Hypothesis: The aim of this study was to examine the occurrence of ventricular arrhythmias and to measureQT parameters in patientswith untreatedOSA using an ambulatory Holter-ECG. Methods: A total of 25 patientswith untreatedOSA were studied. After routine biochemical investigation and2-dimensional, M-mode echocardiography, a 24-hour Holter-ECG was recorded to detect cardiac arrhythmiasand QT parameters. QT parameters were measured by the QT Guard system. Results: Only the QT interval increased significantly during the nighttime period (nocturnal QT interval: 423.1 +/- 34.6 ms, daytime QT interval: 381.6 +/- 33.8 ms, 24-hour QT interval: 394.7 +/- 31.1 ms). However, during the nighttime QT interval (422.8 +/- 14.9 ms), QTd (31.2 +/- 11.0 ms) and QT dispersion (30.5 +/- 10.2 ms) did not show any change compared to 24-hour (QTc interval: 423.7 +/- 14.2 ms, QTd: 28.8 +/- 9.4 ms, QTcd: 30.5 +/- 9.43 ms) and daytime levels (QTc interval: 423.9 +/- 14.3 ms, QTd: 27.3 +/- 10.7 ms, QTcd: 29.9 +/- 11.1 ms). None of the patients had ventricular arrhythmias. Conclusions: QTd and QTcd did not increase during the nighttime period. Our study did not show an increasedrisk of ventricular arrhythmias in this population during the monitoring period.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Clinical Cardiology 33 : 6 (2010), p. E35-E39. -
További szerzők:	Szabó Zoltán (1973-) (belgyógyász, kardiológus) Kun Csaba (1969-) (kardiológus) Munkácsy Csaba Bene Orsolya (1980-) (kardiológus) Magyar Mária Tünde (1970-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Lőrincz István (1950-) (belgyógyász, kardiológus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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