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001-es BibID:	BIBFORM018468
Első szerző:	Szalai Eszter (orvos)
Cím:	Evaluation of the Corneal Endothelium Using Noncontact and Contact Specular Microscopy / Szalai Eszter, Németh Gábor, Berta András, Jr. Módis László
Dátum:	2011
ISSN:	0277-3740
Megjegyzések:	To determine the difference between the endothelial cell density (ECD) and the morphologic measurements assessed with a recently developed noncontact specular microscope compared with a contact endothelial microscope. The agreement between the 2 independent operators was also investigated. Methods: The central corneal endothelium was examined in the right eyes of 41 healthy individuals using automated image analysis programs without correction for a noncontact specular microscope and a contact specular microscope (EM-3000, EM-1000; Tomey, Tennenlohe, Germany). The evaluated parameters such as ECD, average cell area (AVG), and coefficient of variation of the cell area were determined by 2 operators. Conversion factors were also considered to adjust the ECD values. Results: ECD measurements obtained with the noncontact instrument (2734 +/- 287 cells per square millimeter, first operator; 2726 +/- 282 cells per square millimeter, second operator) were significantly higher (P < 0.0001) in comparison with the contact microscope (2283 +/- 206 cells per square millimeter, first operator; 2274 +/- 242 cells per square millimeter, second operator) by both investigators. The contact specular microscope significantly over-estimated (P < 0.0001) AVG and coefficient of variation of the cell area values. Statistically significant correlation (P < 0.0001) was detected in ECD (r = 0.77, first operator) and AVG measurements (r = 0.72, first operator) between the 2 endothelial microscopes. Higher degree of agreement between operators was given when using the noncontact specular microscope compared with the contact instrument. Conclusions: The significant differences and the poor agreement between the automated software options disclosed that the 2 instruments cannot be used interchangeably.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Cornea. - 30 : 5 (2011), p. 567-570. -
További szerzők:	Németh Gábor (1975-) (szemész) Berta András (1955-) (szemész, gyermekszemész) Módis László (1964-) (szemész szakorvos, kontaktológus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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