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001-es BibID:	BIBFORM019235
Első szerző:	Jakab Ferenc
Cím:	A medical nutriment has supportive value in the treatment of colorectal cancer / F. Jakab, Y. Shoenfeld, Á. Balogh, M. Nichelatti, A. Hoffmann, Zs. Kahán, K. Lapis, Á. Mayer, P. Sápy, F. Szentpéteri, A. Telekes, L. Thurzó, A. Vágvölgyi, M. Hidvégi
Dátum:	2003
ISSN:	0007-0920
Megjegyzések:	MSC (Avemar) is a medical nutriment of which preclinical and observational clinical studies suggested an antimetastatic activity with no toxicity. This open-label cohort trial has compared anticancer treatments plus MSC (9 g once daily) vs anticancer treatments alone in colorectal patients, enrolled from three oncosurgical centres; cohort allocation was on the basis of patients' choice. Sixty-six colorectal cancer patients received MSC supplement for more than 6 months and 104 patients served as controls (anticancer therapies alone): no statistical difference was noted in the time from diagnosis to the last visit between the two groups. End-point analysis revealed that progression-related events were significantly less frequent in the MSC group (new recurrences: 3.0 vs 17.3%, P<0.01; new metastases: 7.6 vs 23.1%, P<0.01; deaths: 12.1 vs 31.7%, P<0.01). Survival analysis showed significant improvements in the MSC group regarding progression-free (P=0.0184) and overall survivals (P=0.0278) probabilities. Survival predictors in Cox's proportional hazards were UICC stage and MSC treatment. Continuous supplementation of anticancer therapies with MSC for more than 6 months is beneficial to patients with colorectal cancer in terms of overall and progression-free survival.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	British Journal Of Cancer. - 89 : 3 (2003), p. 465-469. -
További szerzők:	Shoenfeld, Yehuda Balogh Ádám Nichelatti, M. Hoffmann Artúr Kahán Zsuzsa Lapis Károly Mayer Árpád (Budapest) Szentpéteri F. Telekes A. Thurzó L. Vágvölgyi Attila Hídvégi Máté Sápy Péter (1942-) (sebész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI elektronikus változat
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