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001-es BibID:	BIBFORM020319
Első szerző:	Módis László (szemész szakorvos, kontaktológus)
Cím:	Evaluation of the corneal endothelium in patients with diabetes mellitus type I and II / Módis L. Jr., Szalai E., Kertész K., Kemény-Beke A., Kettesy B., Berta A.
Dátum:	2010
ISSN:	0213-3911
Megjegyzések:	The aim of the present study is to determine corneal physiology and endothelial morphology after proper image analysis technique in type I and II diabetic patients. The HbA1c level and the grade of retinopathy were also recorded and correlated with the endothelial parameters. METHODS: 41 eyes of 21 patients with type I and 59 eyes of 30 patients with type II diabetes mellitus (mean age was 40.97 ± 15.46 and 64.36 ± 10.47 years) were examined and compared to age-matched controls. Endothelial cell density (ECD), mean cell area, coefficient of variation of cell area, central corneal thickness, intraocular pressure, and grade of retinopathy were recorded. RESULTS: There was a statistically significant decreased endothelial cell density in type I disease (2428 ± 219 cell/mm2) in comparison with healthy subjects (2495 ± 191 cell/mm2, P=0.02). The diabetic corneas were thicker than normal (P=0.001). The HbA1c level was inversely correlated with the ECD (r=-0.60; P<0.0001) and correlated with the mean endothelial cell area (r=0.60, P<0.0001). Significant correlation was observed between the endothelial morphology and grade of diabetic retinopathy (r=-0.40, ECD; r=0.38, mean cell area; P=0.01 for both). In type II diabetes mellitus no significant difference was found in the evaluated values. CONCLUSIONS: The present study disclosed the alteration of the corneal endothelial morphology in type I diabetes mellitus as compared to normal subjects. The results indicated that type I diabetic corneas are more susceptible to environmental changes than type II corneas.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Histology and Histopathology. - 25 : 12 (2010), p. 1531-1537. -
További szerzők:	Szalai Eszter (1984-) (orvos) Kertész Katalin Kemény-Beke Ádám (1968-2021) (szemész) Kettesy Beáta (1974-) (szemész) Berta András (1955-) (szemész, gyermekszemész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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