Találati lista | Tudóstér

001-es BibID:	BIBFORM022521
Első szerző:	Tóth Dezső (sebész, onkológus)
Cím:	Value of sentinel lymph node mapping using a blue dye-only method in gastric cancer : a single-center experience from North-East Hungary / Tóth D., Kincses Z., Plósz J., Török Miklós, Kovács I., Kiss C., Damjanovich L.
Dátum:	2011
Megjegyzések:	Forty percent of patients with gastric cancer have unnecessarily extended lymph node dissections with higher rates of morbidity and mortality than those in non-extended procedures. Successful sentinel lymph node (SLN) mapping may help to reduce the number of extended lymphadenectomies. METHODS: SLN mapping was investigated by a blue dye-only method in patients with gastric cancer. The first cohort of patients (n = 16) were marked submucosally by an endoscopist and in the second cohort of patients (n = 23) a subserosal injection was performed by the surgeon. RESULTS: Thirty-nine patients, all Caucasians, underwent gastric resection or total gastrectomy with SLN biopsy using patent blue-dye mapping and modified D2 lymphadenectomy. The mapping procedure and the lymphadenectomy were supervised by the same surgeon. A total of 770 lymph nodes were removed and examined. The mean number of blue nodes was 4.3 per patient. In 22/23 cases at least one SLN showed tumor involvement. The sensitivity of SLN mapping was 95.7%, the false-negative rate was 4.3%, and the specificity was 100%. The negative predictive value was 93.8% and the positive predictive value was 100%. In cases of T1 and T2 tumors the sensitivity was 100%. We found the two marking methods (submucosal vs. subserosal) to be equivalent and there was no side-effect of the blue-dye mapping. CONCLUSIONS: Our results suggest that SLN mapping with blue dye alone represents a safe procedure that seems to be adaptable for non-obese patients undergoing open surgery for gastric cancer in the Eastern European region. The procedure has high sensitivity and specificity, especially in cases of T1 and T2 tumors.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Gastric Cancer. - 14 : 4 (2011), p. 360-364. -
További szerzők:	Kincses Zsolt (1961-) (orvos) Plósz János Török Miklós (1976-) (pathológus) Kovács Ilona (1965-) (patológus) Kiss Csongor (1956-) (hematológus, onkológus) Damjanovich László (1960-) (általános sebész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat Szerző által megadott URL DOI
Borító:
Saját polcon: