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001-es BibID:	BIBFORM022639
Első szerző:	Vandenberghe, A.
Cím:	Functional dyspepsia : still a serious challenge for medical practitioners and new drug investigators? A Belgian, French, German and Hungarian opinion / Vandenberghe A., Mion F., Allescher H. D., Roman S., Csiki Z.
Dátum:	2009
Megjegyzések:	The diagnosis of Functional Dyspepsia is based on the identification of long term specific symptoms and the absence of organic lesions. Many pathophysiological mechanisms are intricate and, at least, partially responsible for the syndrome. Widely accepted technical procedures for the identification of these mechanisms are missing. The final etiopathology is not yet established. The relationship between symptoms and putative mechanisms is unclear. At the moment of the prescription, the physician faces a real therapeutic gap. Moreover, Functional Dyspepsia is an evolving area of study and knowledge has to be updated regularly. As a result, consultations for Functional Dyspepsia are usually very challenging and patients look desperately for medical support. It is likely that this disease is both under-diagnosed and under-treated. Classifying patients into symptomatic subgroups is a promising approach proposed by Rome III. It is assumed that these subgroups are based on different pathophysiological mechanisms, and may allow for more specific therapeutic approaches. However the assessment of the symptomatic profiles of patients is time-consuming. It is also a risky process, because the Rome III subgroups have yet to be validated. There are currently no translations of the definitions in the different European languages. Interviews of the patients are biased by cultural, educational and subjective factors. Identification of suitable subjects for clinical trials is uneasy for the same reasons and can explain several recent Research and Development (R&D) failures. Therefore, there is a need for an updated, step by step approach, a real diagnostic algorithm of the consultation including the use of simple, clear, universal and cross-cultural validated tools, as word-figure questionnaires, designed to establish the symptomatic profiles of the patients.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban külföldön készült közlemény
Megjelenés:	Acta Gastro-Enterologica Belgica. - 73 (2009), p. 360-365. -
További szerzők:	Mion, F. Allescher, H. D. Roman, S. Csiki Zoltán (1962-) (belgyógyász, allergológus, klinikai immunológus, reumatológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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