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001-es BibID:	BIBFORM023377
Első szerző:	Schulte-Altedorneburg, Gernot
Cím:	Accuracy of in vivo carotid B-mode ultrasound compared with pathological analysis : intima-media thickening, lumen diameter, and cross-sectional area / Gernot Schulte-Altedorneburg, Dirk W. Droste, Szabolcs Felszeghy, Mónika Kellermann, Vasile Popa, Katalin Hegedüs, Csaba Hegedüs, Martina Schmid, László Módis, E. Bernd Ringelstein, László Csiba
Dátum:	2001
ISSN:	0039-2499
Megjegyzések:	BACKGROUND AND PURPOSE: This study aimed to determine the correlation of in vivo ultrasound measurements of intima-media thickening (IMT), lumen diameter, andcross-sectional area of the common carotid artery (CCA) with correspondingmeasurements obtained by gross pathology and histology. METHODS: Sixty-sixmoribund neurological patients (mean age 71 years) underwent B-mode ultrasound ofthe CCA a few days before death. During autopsy, carotid specimens were removedin toto. Carotid arteries were ligated and cannulated for injection of ahydrophilic embedding material under standardized conditions. The carotidbifurcation was frozen and cut manually in 3-mm cross slices. Digital imageanalysis was carried out to determine the diameter and the cross-sectional areaof the frozen slices of the CCA. IMT was assessed by light microscope. Ultrasonicand planimetric data were compared. RESULTS: Mean measurements of lumen diameterand cross-sectional area were 7.13+/-1.27 mm and 0.496+/-0.167 cm(2),respectively, by ultrasound, and 7.81+/-1.45 mm and 0.516+/-0.194 cm(2),respectively, by planimetric analysis of the unfixed redistended carotid arteries(R(2)=0.389 and 0.497). The mean IMT was 1.005+/-0.267 mm by ultrasound and0.67+/-0.141 mm histologically, resulting in a mean difference of -31%.CONCLUSIONS: Transcutaneous B-mode ultrasound provides a reliable approach for invivo measurements of the cross-sectional area and, less exactly, of the lumendiameter of the CCA. Compared with histological results, in vivo ultrasoundmeasurements of the IMT are systematically larger.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban fém-kerámia határfelület transzmissziós elektronmikroszkóp (TEM) lerepedési szilárdság Adult Aged Anatomy, Cross-Sectional Arteriosclerosis/pathology/ultrasonography Carotid Artery Diseases/pathology/ultrasonography Carotid Artery, Common/pathology/ultrasonography Female Humans Male Middle Aged Tunica Intima/pathology/ultrasonography Tunica Media/pathology/ultrasonography Ultrasonography/methods egyetemen (Magyarországon) készült közlemény
Megjelenés:	Stroke 32 : 7 (2001), p. 1520-1524. -
További szerzők:	Droste, Dirk W. Felszeghy Szabolcs Béla (1972-) (fogorvos, anatómus, kötőszövetbiológus) Kellermann Mónika (1971-) (pszichiáter) Popa, Vasile Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus) Hegedűs Csaba (1953-) (fogszakorvos) Schmid, Martina Módis László (1939-) (anatómus, kötőszövetbiológus) Ringelstein, E. Bernd Csiba László (1952-) (neurológus, pszichiáter)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI elektronikus elérés
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