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001-es BibID:	BIBFORM023724
Első szerző:	Soós Györgyike (pathológus)
Cím:	The prevalence of prostate carcinoma and its precursor in Hungary : an autopsy study / Gyorgyike Soos, Ioannis Tsakiris, Janos Szanto, Csaba Turzo, P. Gabriel Haas, Balazs Dezso
Dátum:	2005
ISSN:	0302-2838
Megjegyzések:	The prevalence of incidental prostatic adenocarcinoma (PCa) and its precursor, high grade intraepithelial neoplasia (HGPIN) in an autopsy series from Hungarians (Central European Caucasians) was assessed and compared to similar data from the United States and European countries. METHODS: Autopsy cases (n=139; 18-95 years) with no history of urological disease were histologically examined for prostate cancer and HGPIN. After en block removal, the prostate glands were fixed in formalin, sectioned at 3-5mm intervals and embedded in paraffin. Whole-mount serial sections were stained with Hematoxylin-eosin and examined for the presence of PCa and HGPIN. The frequency of PCa and HGPIN was compared to autopsy data obtained from other geographical areas. RESULTS: We found a 38.8% prevalence of incidental PCa with increasing age-related incidence. Both PCa and HGPIN are first detected in the 3rd decade and show a steady increase with age with respect to number of foci, tumor grade and volume. In the age group 81-95, 86.6% and 60% of men had PCa and HGPIN, respectively. CONCLUSIONS: Incidental PCa and HGPIN are very prevalent in Hungarian population, comparable with the high US and the Scandinavian epidemiological data for Caucasians.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	European Urology. - 48 : 5 (2005), p. 739-744. -
További szerzők:	Tsakiris, Ioannis (1976-) (orvos) Szántó János (1949-) (onkológus szakorvos) Turzó Csaba (1962-) (igazságügyi orvosszakértő) Haas, Gabriel P. Dezső Balázs (1951-) (pathológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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