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001-es BibID:	BIBFORM024364
Első szerző:	Szabó László
Cím:	Urinary flow disturbance as an early sign of autonomic neuropathy in diabetic children and adolescents' / Laszlo Szabo, Laszlo Barkai, Bela Lombay
Dátum:	2007
Megjegyzések:	Aims: Urinary bladder dysfunction is a frequent complication of diabetes mellitus in adults. The aim of this study is to determine the early disturbances of the detrusor contractility in children, and adolescents with type 1 diabetes. Materials and Methods: The bladder urine flow parameters were investigated in 37 children with type 1 diabetes, 10/37 with cardiovascular autonomic dysfunction (CAD) voided 482 ? 128 mils (Group A), 27/37 without CAD voided 258 ? 52 mils (Group B). From an earlier uroflow screening study 20 healthy children formed group control A, who had voided 488 ? 94 mils, and another 30 healthy children formed group control B, who had voided 260 ? 50 mils. The compared groups were matched for voided volume, age, weight, and height. There was no evidence of urinary tract abnormalities in any of the children. Results: Time to maximum flow was longer in both diabetic groups as compared with controls (P < 0.01), and the acceleration (the ratio of maximum flow and the time to maximum flow) of diabetics was significantly lower (P < 0.01). Bladder emptying was complete in each subject. Bladder wall disturbances were not seen by ultrasound. Conclusions: The decreased acceleration of detrusor muscle contraction may be interpreted as an early sign of autonomic neuropathy in children and adolescent with type 1 diabetes, even in patients without CAD. Clinicians may be able to determine autonomic neuropathy by using uroflowmetry that is easy to perform, sensitive, reproducible, and needs only a child's minimal cooperation. ? 2006 Wiley-Liss, Inc. PubMed ID: 17078072 UR: http://www.scopus.com/inward/record.url?eid=2-s2.0-34247117315&partnerID=40&md5=bd1e153db61a720d281c7d143a09fe61
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Urodynamics Urinary Bladder Prospective Studies Muscle, Smooth Male Humans Heart Rate Female Diabetic Neuropathies Diabetes Mellitus, Type 1 Child Blood Pressure Autonomic Nervous System Diseases Adolescent Uroflowmetry urine incontinence Sensitivity analysis reproducibility onset age muscle contractility micturition insulin dependent diabetes mellitus human Early Diagnosis DIABETIC NEUROPATHY detrusor dyssynergia COOPERATION controlled study clinical article cardiovascular disease Body Weight Body Height bladder dysfunction ARTICLE Adult Urine flow acceleration Diabetic cystopathy diabetes mellitus
Megjelenés:	Neurourology and urodynamics. - 26 : 2 (2007), p. 218-221. -
További szerzők:	Barkai László (1958-) (gyermekgyógyász) Lombay Béla Jr.
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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