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001-es BibID:	BIBFORM024860
Első szerző:	Márton Ildikó (fogszakorvos)
Cím:	Characterization of inflammatory cell infiltrate in dental periapical lesions / I. J. Marton, C. Kiss
Dátum:	1993
ISSN:	0143-2885
Megjegyzések:	Sixty-three dental periapical lesions were investigated in order to study the involvement of inflammatory and immunologic reactions in the pathogenesis and maintenance of chronic apical periodontitis. Of 61 well-preserved specimens, 38 were classified as granulomatous, 3 as exudative periapical granulomas and 20 as periapical scars. The quantitative composition of T-lymphocyte subpopulation and macrophages, the proportion of IgE-producing cells compared with other immunoglobulin producing plasma cells, and the tissue distribution of IgE-producing plasma cells compared with that of mast cells were determined in the granulomatous types of granulomas using immunofluorescent, immunohistochemical and enzymehistochemical methods. The results indicated a decreased ratio of helper/inducer versus cytotoxic/suppressor T-lymphocytes, a remarkably high proportion of macrophages, a low frequency of IgE-producing plasma cells with different localization when compared with that of mast cells. These observations suggest that T-lymphocytes and macrophages may play an important role in the complex events of tissue destruction and repair taking place in the periapical region.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	International Endodontic Journal. - 26 : 2 (1993), p. 131-136. -
További szerzők:	Kiss Csongor (1956-) (hematológus, onkológus)
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