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001-es BibID:	BIBFORM029650
Első szerző:	Zs. Nagy Imre
Cím:	Energy-dispersive, bulk specimen X-ray microanalytical measurement of the intracellular Na+/K+ ratio in human laryngeal tumors / I. Zs. Nagy, L. Tóth, Z. Szállási, I. Lampé
Dátum:	1987
Megjegyzések:	Energy-dispersive X-ray microanalysis was performed on human biopsy materials taken during laryngoscopic intervention in 18 cases. The removed tissue pieces were divided into two parts. One of them was used for pathohistological studies, the other was processed for X-ray microanalysis by the freeze-fracture freeze-drying method. Of the cases investigated 4 proved to be of benign character, whereas the rest contained carcinoma planocellulare keratoides or nonkeratoides. Bulk specimen energy-dispersive X-ray microanalysis of 135 cells from the benign tissue samples revealed an average Na+/K+ molar ratio of 0.13 + 0.01 (SEM) in the intracellular space, with a regular Gaussian distribution. In the cases of carcinomas 641 cells were measured, the average of the sameratio was 0.67 + 0.03 (SEM) due mostly to an increasein the Na+ content. The distribution of data was apparentlynot normal in the cancerous samples. These observations and some theoretical considerations support the notion that the intracellular Na+/K+ ratio correlates with the proliferative capacity of tissues.The relevance of some recent biochemical results is also discussed in this respect.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Intracellular Na+ content Mitogenesis X-ray microanalysis Laryngeal tumors Human biopsy egyetemen (Magyarországon) készült közlemény
Megjelenés:	Journal of cancer research and clinical oncology 113 : 2 (1987), p. 197-202. -
További szerzők:	Tóth László (1957-) (fül-orr-gégész) Szállási Zoltán Lampé István (1932-) (fül-orr-gégész, audiológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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