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001-es BibID:	BIBFORM029803
Első szerző:	Polgár Erika
Cím:	Immunohistochemical localization of neurokinin-l receptor in the lumbar spinal cord of young rats : morphology and distribution / Erika Polgár, Péter Szűcs, László Urbán, Klára Matesz, István Nagy
Dátum:	1999
Megjegyzések:	The type and distribution of neurokinin-1 (NK-1) receptor-expressing neurones were studied in young (14-day-old) rats' lumbar spinal cord using pre-embedding immunohistochemistry. The heaviest immunoreactivity was observed in the middle part and lateral fourth of lamina I where the great majority of immunoreactive perikarya represented fusiform and multipolar cells. In lamina II the middle and medial part showed moderate immunoreactivity, most of the cells resembled stalked cells. In lamina III the labelled perikarya were evenly distributed, while those in lamina IV accumulated mainly in the lateral part. In both laminae most of the labelled neurones represented central cells, the rest of them belonged to the antenna-type cells with long dorsally directed dendrites penetrating the superficial laminae. The immunoreactivity in laminae V-VII was uniform and relatively weak. In lamina VIII the immunopositive perikarya were encountered only rarely while in lamina IX virtually all motoneurones showed weak immunoreactivity. Lamina X contained small, multipolar and fusiform labelled perikarya. In conclusion, we found that the general appearance of the NK-1 receptor immunostaining and the major type of NK-I receptor-expressing neurones were similar to that found previously in adult spinal cord. Using the same method as Brown and colleagues the number of labelled NK- 1 receptor immunoreactive cells was similar in young and adult animals except lamina I where the number of immunoreactive neurones was twice that in adults.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Somatosensory and Motor Research. - 16 : 4 (1999), p. 361-368. -
További szerzők:	Szűcs Péter (1974-) (kutatóorvos) Urbán László (London, UK) Matesz Klára (1949-) (anatómus, neurobiológus) Nagy István (orvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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