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001-es BibID:	BIBFORM030927
Első szerző:	Németh Norbert (kutatóorvos)
Cím:	Local and systemic hemorheological effects of cerebral hyper- and hypoperfusion in a porcine model / Németh N., Soukup J., Menzel M., Henze D., Clausen T., Rieger A., Holz C., Scharf A., Hanisch F., Furka I., Mikó I.
Dátum:	2006
ISSN:	1386-0291
Megjegyzések:	Using a well defined pig model, we investigated whether cerebral hypertension and hypotension influence hemorheological factors. After surgical preparation and stabilization, periods of hyperventilation, controlled periods of cerebral perfusion pressure increases and decreases were utilized. After each period, blood samples were collected from the cannulated femoral artery and vein, and from the superior sagittal sinus. Erythrocyte deformability, whole blood and plasma viscosity and hematological parameters were determined. Erythrocyte deformability significantly worsened in arterial samples after hypertension and hypotension, and in sinus samples it was impaired after hypotension period. Hematocrit significantly increased in arterial and sinus samples during hypertensive period, accompanied by similar alterations in whole blood viscosity. We conclude that hemodynamic changes caused by hyperventilation, hyper- or hypotension can influence hemorheological factors, and suggest that the rheological alterations can affect local hemodynamic and metabolic conditions.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Clinical Hemorheology And Microcirculation. - 35 : 1-2 (2006), p. 59-65. -
További szerzők:	Soukup, Jens Menzel, Matthias (sebész) Henze, Dirk Clausen, Tobias Rieger, Andreas Holz, Carsten Scharf, Alexander Hanisch, Frank Furka István (1935-2021) (sebész, urológus, kutatóorvos) Mikó Irén (1948-) (kutató sebész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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