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001-es BibID:	BIBFORM034825
Első szerző:	Tornai István (belgyógyász, gasztroenterológus)
Cím:	Heterogeneous regeneration of motor fibers following union of the ventral and the dorsal roots in frogs / I. Tornai, L. Urbán, G. Székely
Dátum:	1983
ISSN:	0236-5383
Megjegyzések:	In frogs, the dorsal and ventral roots of one of the large lumbar segments (8th or 9th) of the spinal cord were severed and the central stumps were united in order to let motor fibers of the ventral root regenerate into the spinal cord via the dorsal root. After a survival period of 7 to 30 weeks, regeneration was tested in stimulation experiments and in histological investigations. Stimulation experiments involved recordings of field potentials and ventral root potentials evoked by stimulation of the regenerated dorsal root. Appreciable responses could be recorded only from a fraction of the animals investigated. Histological investigation following cobalt labelling of the united dorsal root revealed the presence of a significant amount of regenerated fibers. The arborization pattern of some regenerated fibers resembled the muscle end-plate formation. The results indicate that cholinergic motor fibers are able to replace, to a limited extent, dorsal root fibers. This suggests that there is not a strict receptor-nerve specificity in the sense that a synaptic site can be exclusively stimulated by the appropriate mediator, but rather a preferential selection for the appropriate connection. This preference is higher when both the morphology and the chemistry of the presynaptic structure match with the postsynaptic medium.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Acta Biologica Hungarica. - 34 : 1 (1983), p. 45-54. -
További szerzők:	Urbán László (London, UK) Székely György (1926-2017) (neurobiológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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