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001-es BibID:	BIBFORM036850
Első szerző:	Pap Zoltán
Cím:	Thrombocytafunkció-zavar albínó gyermekekben / Pap Zoltán, Ajzner Éva, Kiss Csongor, Emődy Judit, Závodszky Ildikó, Horváth Andrea, Muszbek László
Dátum:	1997
Megjegyzések:	Seven children with albinism were examined for haemorrhagic diathesis. In 6 patients coagulation screening tests (prothrombin time, activated partial thromboplastin time,thrombin time) were normal, in 1 patient prolongation of activated partial thromboplastin time due to mild factor XI deficiency was found. Platelet counts were in the reference range, however, the template bleeding time of 6 out of 7 patients was prolonged. Evaluation of platelet aggregation and secretion in a lumi-aggregometer demonstrated that only the child with normal bleeding time had normal platelet function, and 6 children with prolonged bleeding time had impaired aggregation and release reaction. Five out of these 6 patients had severe decrease of ATP secretion even when high dose of thrombin was used as agonist. The number of dens granules in the platelets of these patients, as measured by the uptake of mepacrine, was significantly clearly suggested storage pool deficiency. In one of these patients storage pool deficiency was associted with mild factor XI deficiency. The high frequency of haemorrhagic diathesis in albino children emphasizes, the importance of the screening of patients with albinism for bleeding diathesis.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban folyóiratcikk Thrombocytafunkció-zavar egyetemen (Magyarországon) készült közlemény
Megjelenés:	Orvosi Hetilap. - 137 : 8 (1997), p. 467-471. -
További szerzők:	Ajzner Éva (1968-) (laboratóriumi szakorvos) Kiss Csongor (1956-) (hematológus, onkológus) Emődy Judit (szemorvos) Závodszky Ildikó Horváth Andrea Muszbek László (1942-) (haematológus, kutató orvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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