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001-es BibID:	BIBFORM037296
Első szerző:	Bartha Lajos
Cím:	A clinical feasibility study to evaluate the safety and efficacy of PEOT/PBT implants for human donor site filling during mosaicplasty / Bartha Lajos, Hamann Doreen, Pieper Jeroen, Péters Fabienne, Riesle Jens, Vajda Andras, Pal Kaposi Novak, Hangody Laszlo Rudolf, Vasarhelyi Gabor, Bodó Laszlo, Blitterswijk Clemens, de Wijn Joost, Kenyeres Annamaria, Modis Laszlo, Balo Eszter, Hangody Laszlo
Dátum:	2013
ISSN:	1633-8065
Megjegyzések:	Mosaicplasty has become a well-accepted treatment modality for articular cartilage lesions in the knee. Postoperative bleeding remains potentially concerning. This study evaluates the porous poly(ethylene oxide)terephthalate/poly(butylene terephthalate) (PEOT/ PBT) implants used for donor site filling. Empty donor sites were the controls. After 9 months, MRI, macroscopical and histological analysis were carried out. Treated defects did not cause postoperative bleeding. No adverse events or inflammatory response was observed. PEOT/PBT implants were well integrated. Empty controls occasionally showed protrusion of repair tissue at the defect margins. Surface stiffness was minimally improved compared to controls. Existing polymer fragments indicated considerable biodegradation. Histological evaluation of the filled donor sites revealed congruent fibrocartilaginous surface repair with proteoglycan-rich domains and subchondral cancellous bone formation with interspersed fibrous tissue in all implanted sites. The PEOT/PBT implants successfully reduce donor site morbidity and postoperative bleeding after mosaicplasty.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	European Journal of Orthopaedic Surgery and Traumatology 23 : 1 (2013), p. 81-91. -
További szerzők:	Hamann, Doreen Pieper, Jeroen Péters, Fabienne Riesle, Jens Vajda András Kaposi Novák Pál Hangody László Rudolf Vásárhelyi Gábor Bodó László Blitterswijk, Clemens de Wijn, Joost Kenyeres Annamária (1980-) (analitikus) Módis László (1939-) (anatómus, kötőszövetbiológus) Baló Eszter (1979-) (orvos) Hangody László
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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