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001-es BibID:	BIBFORM040890
035-os BibID:	PMID:23339999
Első szerző:	Németh Norbert (kutatóorvos)
Cím:	Testicular ischemia-reperfusion may alter micro-rheological parameters in laboratory rats / Norbert Németh, Ferenc Kiss, Zoltán Klárik, Katalin Pető, Erzsébet Ványolos, László Tóth, István Furka, Irén Mikó
Dátum:	2014
ISSN:	1386-0291
Megjegyzések:	Ischemia-reperfusion-caused hemorheological alterations have been widely studied but the effect of testicular ischemia-reperfusion has not so far. In this study 14 Sprague-Dawley rats were involved. In the ischemia-reperfusion group under general anaesthesia the left testis was explored by opening the scrotum then the deferent duct and vasculature were clamped for 30 minutes. Testicular microcirculation was monitored by laser Doppler flowmetry. The right testis was untouched. In the control group: only anaesthesia was induced. Blood sampling occurred before and after ischemia, at the 60th minute of reperfusion and on the 1st postoperative day for determining hematological parameters (microcell-counter), erythrocyte deformability (slit-flow ektacytometer) and erythrocyte aggregation (light-transmission aggregometer). After the last blood sampling, testicles were removed for histological examination. Hematological parameter changes reflected inflammatory response. Erythrocyte deformability showed a worsening already at the 60th minute of reperfusion compared to base and control values. By the 1st postoperative day further decrease was observed. Erythrocyte aggregation significantly enhanced with great magnitude versus base and control values (p < 0.001). However, conventional histological examinations did not show marked testicular injury. The experienced changes can attract attention to the testicular ischemia-reperfusion causing significant effects on hemorheological parameters, which can lead to further harmful microcirculatory consequences.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Clinical Hemorheology and Microcirculation 57 : 3 (2014), p. 243-253. -
További szerzők:	Kiss Ferenc (1982-) (kutatóorvos) Klárik Zoltán (1985-) Pető Katalin (1961-) (kutatóorvos) (Kísérletes orvostudomány) Ványolos Erzsébet (sebészeti műtéttan) Tóth László (1971-) (patológus) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Mikó Irén (1948-) (kutató sebész)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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