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001-es BibID:	BIBFORM042759
Első szerző:	Góth László (analitikus)
Cím:	Catalase deficiency may complicate urate oxidase (rasburicas) therapy / László Góth, N. William Bigler
Dátum:	2007
ISSN:	1071-5762
Megjegyzések:	Patients with low (inherited and acquired) catalase activities who are treated with infusion of uric acid oxidase because they are at risk of tumour lysis syndrome may experience very high concentrations of hydrogen peroxide. They may suffer from methemoglobinaemia and haemolytic anaemia which may be attributed either to deficiency of glucose-6-phosphate dehydrogenase or to other unknown circumstances. Data have not been reported from catalase deficient patients who were treated with uric acid oxidase. It may be hypothesized that their decreased blood catalase could lead to the increased concentration of hydrogen peroxide which may cause haemolysis and formation of methemoglobin. Blood catalase activity should be measured for patients at risk of tumour lysis syndrome prior to uric acid oxidase treatment.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok kritika tumor lysis syndrome urtae oxidase treatment catalase deficiency hemolysis blood catalase
Megjelenés:	Free Radical Research. - 41 : 9 (2007), p. 953-955. -
További szerzők:	Bigler, William N.
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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