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001-es BibID:	BIBFORM049640
035-os BibID:	PMID:24297095
Első szerző:	Bazsó A. (Budapest)
Cím:	Aseptic necrosis at multiple localisations in a lupus patient with lymphoma / A. Bazso, T. Bazso, P. Szodoray, G. Poor, E. Kiss
Dátum:	2014
ISSN:	0937-941X
Megjegyzések:	Avascular or aseptic necrosis is a well-defined entity leading to the degradation of cellular elements of the bone. The pathogenesis of osteonecrosis (ON) is still unknown. There are two main types of ON: traumatic or non-traumatic. Several clinical entities could associate with ON, systemic diseases, environmental factors, pregnancy, systemic autoimmune or rheumatic diseases, thrombophilia, corticosteroid therapy, cytotoxic dugs, infections, metabolic and hematologic diseases, etc. Corticosteroids (CS) are still the most frequently used therapeutic options in the early phase and during flares of these diseases. Inflammatory cytokines and antibodies have been described to participate in the pathogenesis of ON. The infiltrative disorders of the bone marrow could also contribute to the development of ON. Hereby, we describe a female patient with NHL followed by SLE in whom ON has developed at least in two localisations. Lupus flare, long-term CS therapy, lymphoma relapse or the presence of antiphospholipid antibodies were excluded. Although the bi-localised ON could be contributed to immunologic factors or trauma, the exact aetiology in this case could not be elucidated.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Osteoporosis International 25 : 4 (2014), p. 1415-1417. -
További szerzők:	Bazsó Tamás (1974-) (ortopéd sebész) Szodoray Péter (1973-) (belgyógyász, orvos) Poór Gyula Kiss E.
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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