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001-es BibID:	BIBFORM050117
Első szerző:	Hajdu István (vegyész)
Cím:	Nanoparticles prepared by self-assembly of Chitosan and poly-γ-glutamic acid / Istvan Hajdu, Magdolna Bodnár, Genovéva Filipcsei, John F. Hartmann, Lajos Daróczi, Miklós Zrínyi, János Borbély
Dátum:	2007
ISSN:	0303-402X
Megjegyzések:	The present paper describes the preparation and characterization of novel biodegradable nanoparticles based on self-assembly of poly-gamma-glutamic acid (γ-PGA) and chitosan (CH). The nanosystems were stable in aqueous media at low pH conditions. Solubility of the systems was determined by turbidity measurements. Surface charge and mobility were measured electrophoretically. The particle size and the size distribution of the polyelectrolyte complexes were identified by dynamic light scattering and transmission electron microscopy (TEM). It was found that the size and size distribution of the nanosystems depends on the concentrations of γ-PGA and CH solutions and their ratio as well as on the pH of the mixture and the order of addition. The diameter of individual particles was in the range of 20-285 nm measured by TEM, and the average hydrodynamic diameters were between 150 and 330 nm. These biodegradable, self-assembling stable nanocomplexes might be useful for several biomedical applications.
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban γ-PGA Chitosan Polyelectrolyte Nanoparticles Complexation Self-assembly Electrophoretic mobility
Megjelenés:	Colloid and Polymer Science. - 286 : 3 (2007), p. 343-350. -
További szerzők:	Bodnár Magdolna Filipcsei Genovéva Hartmann, John F. Daróczi Lajos (1965-) (fizikus) Zrínyi Miklós (kémikus) Borbély János (1950-) (vegyész)
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