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001-es BibID:	BIBFORM050620
Első szerző:	Barta Kitti (belgyógyász)
Cím:	Hemodiafiltration beneficially affects QT interval duration and dispersion compared to hemodialysis / Kitti Barta, Árpád Czifra, Csaba Kun, Alida Páll, Julianna Kulcsár, György Paragh, István Lőrincz, Tamás János Padra, Anupam Agarwal, Zarjou Abolfazl, József Balla, Zoltán Szabo
Dátum:	2014
ISSN:	1342-1751 1437-7799
Megjegyzések:	BACKGROUND/AIMS:The prolongation of the QT interval and dispersion could predict ventricular arrhythmias. It is not yet established whether there is a difference between the effects of hemodialysis and hemodiafiltration on QT interval duration and dispersion.METHODS:Data of thirty patients was investigated while they were receiving hemodiafiltration over a period of 3 months; then the same group of patients was evaluated during treatment with conventional hemodialysis for at least another 3 months. Ionic parameters and surface electrocardiograms (ECG) were analyzed five times during each session, and 2D, M-mode echocardiography and Holter ECGs were performed to acquire additional information.RESULTS:QT interval duration (QTmax) and dispersion (QTd) showed a significant increase during hemodialysis, but not during hemodiafiltration. QTmax was 388.66 ? 31.81 ms at the beginning of hemodialysis and increased to 400.66 ? 39.12 ms even at the 30th minute (p < 0.05). QTd was found to be 31.33 ? 10.08 ms before the commencement of hemodialysis with the largest prolongation being seen at the 240th minute (51.33 ? 14.56 ms, p < 0.05). The occurrence of ventricular premature beats was significantly higher during hemodialysis (p = 0.018). The left atrial diameter significantly decreased at the end of hemodiafiltration (at the beginning 45.1 ? 5.25 mm, at the end 40.77 ? 5.76 mm; p < 0.05).CONCLUSION:Our results suggest a beneficial effect of hemodiafiltration on the studied electrocardiographic parameters compared to hemodialysis. The larger decrease in the left atrial diameter suggests a more efficient intracardiac volume-decreasing potential of hemodiafiltration.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Hemodiafiltration Hemodialysis Ventricular arrhythmias QT interval QT dispersion
Megjelenés:	Clinical and Experimental Nephrology. - 18 : 6 (2014), p. 952-959. -
További szerzők:	Czifra Árpád (1983-) (belgyógyász) Kun Csaba (1969-) (kardiológus) Páll Alida (1983-) (orvos) Kulcsár Júlia (1983-) (orvos) Paragh György (1953-) (belgyógyász) Lőrincz István (1950-) (belgyógyász, kardiológus) Padra János Tamás (1984-) (biológus) Agarwal, Anupam Zarjou, Abolfazl (1979-) (kutató orvos) Balla József (1959-) (belgyógyász, nephrológus) Szabó Zoltán (1973-) (belgyógyász, kardiológus)
Pályázati támogatás:	TÁMOP-4.2.2.A-11/1/KONV-2012-0045 TÁMOP Belgyógyászat Kutatócsoport
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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