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001-es BibID:	BIBFORM051328
035-os BibID:	PMID:24000054
Első szerző:	Klárik Zoltán
Cím:	A modified microsurgical model for end-to-side selective portacaval shunt in the rat. Intraoperative microcirculatory investigations / Zoltan Klárik, Enikő Tóth, Ferenc Kiss, Irén Mikó, István Furka, Norbert Németh
Dátum:	2013
ISSN:	0102-8650 1678-2674
Megjegyzések:	PURPOSE: To investigate the intraoperative microcirculatory changes of the affected organs (small bowel, liver and kidney) during the making of a modified selective portacaval (PC) shunt. METHODS: On ten anaesthetized Sprague-Dawley rats the selective end-to-side mesocaval anastomosis was performed, where only the rostral mesenteric vein is utilized and the portal vein with the splenic vein are left intact. Morphometric and microcirculatory investigations using a LDF device determining flux units (BFU) were carried out. RESULTS: After completing the shunts the microcirculatory flux values did not recover in the same manner on the surface of the small intestine, the liver or the kidney. BFU values showed deterioration in the small intestine and in the liver (p<0.001). During the reperfusion the BFU values improved, but not in the same manner. The small intestine values left behind the kidney and liver data. CONCLUSIONS: Technically, the advantages of the models include the selective characteristic, the mesocaval localization and the relatively easy access to those vessels. However, its major disadvantage is the time needed for positioning the vessels without coiling or definitive stretching. Intraoperative LDF may provide useful data on the microcirculatory affection of the organs suffering from hypoperfusion or ischemia during creating the shunts.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Acta Cirúrgica Brasileira. - 28 : 9 (2013), p. 625-631. -
További szerzők:	Tóth Enikő Kiss Ferenc Mikó Irén (1948-) (kutató sebész) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Németh Norbert (1975-) (kutatóorvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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