Találati lista | Tudóstér

001-es BibID:	BIBFORM058216
Első szerző:	Baré, S. N.
Cím:	Factor V Leiden as a risk factor for miscarriage and reduced fertility / S. N. Baré, R. Póka, I. Balogh, É. Ajzner
Dátum:	2000
ISSN:	0004-8666
Megjegyzések:	The Leiden mutation is a recent discovery. It is the main cause of inheritedthrombophilia and has been found in 20-60% of deep vein thrombosis cases. Morerecently it has been found in a significant number of cases of obstetriccomplications attributable to placental thrombosis. Current patient managementpractice for dealing with the Leiden mutation is based mainly on informationabout deep vein thrombosis because there is little information on pregnancycomplications. There are no prospective studies examining the risk of developingpregnancy complications for Leiden mutation carriers. The aim of this study is todo that by comparing the frequency of unfavourable pregnancy outcomes amongcarriers with those among controls. The number of women developing miscarriages,intrauterine deaths, or infertility problems among 128 Leiden mutation carrierswas compared with the number among 461 controls. The risk of having at least onemiscarriage or infertility problems was 1.5 times greater for Leiden mutationcarriers than controls. This result was statistically significant (95% CI 1.2,2.7). The risk of having at least two miscarriages or infertility problems was2.5 times greater for Leiden mutation carriers than controls. This was alsostatistically significant (95% CI 1.2, 5.13).
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Australian & New Zealand Journal of Obstetrics & Gynaecology. - 40 : 2 (2000), p. 186-190. -
További szerzők:	Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Balogh István (1972-) (molekuláris biológus, genetikus) Ajzner Éva (1968-) (laboratóriumi szakorvos)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: