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001-es BibID:	BIBFORM063682
Első szerző:	Viski Sándor Zsolt (orvos)
Cím:	Effect of reading on blood flow changes in the posterior cerebral artery in early blind and sighted people : a transcranial Doppler study / Sandor Viski, David Orgovan, Katalin Szabo, Bernhard Rosengarten, Laszlo Csiba, Laszlo Olah
Dátum:	2016
ISSN:	0022-510X
Megjegyzések:	BackgroundNeuroimaging studies proved that Braille reading resulted in visual cortex activation in blind people, however, very few data are available about the measure of flow increase in these subjects. Therefore, we investigated the flow response in the posterior cerebral artery (PCA) of eleven early blind and ten sighted subjects induced by reading Braille and print, respectively.MethodsTwo experimental protocols were used in both groups: PCA flow velocity during reading was compared to the resting phase and "NLC" phase (volunteers "read" non-lexical characters; e.g. .,-.:,-.:...,). The use of these experimental protocols allowed to investigate separately the effect of "light stimulus + print reading" versus "print reading alone" in sighted, and "hand/finger movement + Braille reading" versus "Braille reading alone" in blind subjects.ResultsThe flow response in the PCA evoked by "Braille reading alone" in blind (10.5 ? 4.5%) and "print reading alone" in sighted subjects (8.1 ? 3.5%) was similar. The flow increase induced by "hand/finger movement + Braille reading" and by "Braille reading alone" did not differ in blind people, however, "light stimulus + print reading" in sighted subjects caused higher PCA flow increase (25.9 ? 6.9%) than "print reading alone" (8.1 ? 3.5%).ConclusionThe similar PCA flow response induced by Braille and print reading alone suggested a similar degree of occipital cortex activation in blind and sighted subjects. In sighted people, the 3-times higher flow velocity increase induced by "light stimulus + print reading" compared with "print reading alone" indicated that 2/3 of PCA flow increase during reading was due to the light stimulus and only 1/3 of flow response was caused by reading alone.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Cortical activation Blind subjects Cerebral blood flow Neurovascular coupling Transcranial Doppler
Megjelenés:	Journal Of The Neurological Sciences 363 (2016), p. 132-139. -
További szerzők:	Orgovan, David Szabó Katalin Judit (1984-) (neurológus) Rosengarten, Bernhard Csiba László (1952-) (neurológus, pszichiáter) Oláh László (1967-) (neurológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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