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001-es BibID:	BIBFORM064128
Első szerző:	Gámán György
Cím:	Biliary Complications After Orthotopic Liver Transplantation: The Hungarian Experience / G. Gámán, F. Gelley, A. Doros, G. Zádori, D. Görög, I. Fehérvári, L. Kóbori, B. Nemes
Dátum:	2013
ISSN:	0041-1345
Megjegyzések:	ABSTRACTBiliary complications (BC) significantly affect morbidity and mortality after orthotopic livertransplantation (OLT). The aim of this study was to analyze the incidence and types ofbiliary complications after OLT in Hungary. We retrospectively analyzed data of 471 adultliver transplant recipients between 1995 and 2011. Biliary complications occurred in 28%of patients. The most frequent BCs were bile duct stricture, stenosis (19%), biliary leakage(12%), and necrosis (BN: 6.4%). Biliary complications were associated with the incidenceof acute rejection (51% vs 31%; P ? .003), hepatic artery thrombosis (43% vs 11%;P < .001), and hepatic artery stenosis (26% vs 11%; P ? .002). When cold ischemic timewas longer than 12 hours, leakage (10% vs 3%; P ? .043), ischemic type biliary lesion (20%vs 3.4%; P ? .05), and BN (12% vs 3%; P ? .067) were more often diagnosed post-OLT.Most of the biliary complications were treated by radiologic interventions (70%). Bile ductnecrosis was associated with lower graft and patient survival. In conclusion, acute rejection,hepatic artery thrombosis/stenosis and cold ischemic time longer than 12 hours increase theincidence of BCs. Successful management of these risk factors can reduce the incidenceof biliary complications and improve mortality.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Orthotopic Liver Transplantation liver transplantation extended criteria donor survival outcome complications
Megjelenés:	Transplantation Proceedings 45 : 10 (2013), p. 3695-3697. -
További szerzők:	Gelley Fanni Doros Attila Zádori Gergely (1983-) (sebész) Görög Dénes Fehérvári Imre Kóbori László Nemes Balázs Áron (1969-) (sebész)
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