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001-es BibID:	BIBFORM064147
Első szerző:	Gelley Fanni
Cím:	Relationship Between Hepatitis C Virus Recurrence and De Novo Diabetes After Liver Transplantation: The Hungarian Experience / F. Gelley, G. Zadori, G. Firneisz, L. Wagner, I. Fehervári, Z. Gerlei, J. Fazakas, S. Papai, G. Lengyel, E. Sarvary, B. Nemes
Dátum:	2011
ISSN:	0041-1345
Megjegyzések:	De novo diabetes mellitus is a common complication after liver transplantation. It isstrongly associated with hepatitis C virus (HCV) infection. We analyzed the relationshipbetween HCV recurrence and de novo diabetes among the Hungarian livertransplant population. This retrospective study included cases from 1995 to 2009 on310 whole liver transplantations. De novo diabetes was defined if the patient had afasting plasma glucose 126 mg/dL permanently after the third month post livertransplantation, and/or required sustained antidiabetic therapy. De novo diabetesoccured in 63 patients (20%). The cumulative patient survival rates at 1, 3, 5, and 8years were 95%, 91%, 88%, and 88% in the control group, and 87%, 79%, 79%, and64% in the de novo group, respectively (P .011). The majority of the patients in thede novo group were HCV positive (66% vs 23%). Early virus recurrence within 5months was associated with the development of diabetes (80% vs 20% non-diabeticcontrols; P .017). The fibrosis (2.05 1.5 vs 1 1; P .039) and Knodell scores(3.25 2 vs 1.69 1.2; P .019) were higher among the de novo group after antiviraltherapy. Rapid recurrence, more severe viremia, and fibrosis showed significant rolesin the developement of de novo diabetes after liver transplantation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Transplantation Proceedings. - 43 : 4 (2011), p. 1281-1282. -
További szerzők:	Zádori Gergely (1983-) (sebész) Firneisz Gábor Wagner László Fehérvári Imre Gerlei Zsuzsa Fazakas János Pápai Simon Lengyel Gabriella Sárváry Enikő Nemes Balázs Áron (1969-) (sebész)
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