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001-es BibID:	BIBFORM064563
Első szerző:	Murányi Mihály (urológus)
Cím:	Successful laparoscopic radical prostatectomy in a patient with factor XI deficiency / Mihály Murányi, Mátyás Benyó, Zoltán Kiss, Tibor Flaskó
Dátum:	2016
ISSN:	0976-3198
Megjegyzések:	Introduction: Factor XI deficiency is a rare type of hemophilia. It is associated with profuse bleeding after traumas and surgical procedures. In a patient with factor XI deficiency, the serum coagulation factor level does not predict bleeding tendency appropriately. Operations in sites without fibrinolytic activity are less likely to be complicated by bleeding, while surgery in areas with fibrinolytic activity, like prostatectomy, increases the risk of bleeding. The optimal treatment should be determined by individual circumstances. Radical prostatectomy is a procedure when severe bleeding requiring transfusion can occur even without any bleeding disorder. At the same time radical prostatectomy carries a significant risk of potentially fatal thromboembolism. Thus keeping the balance between procoagulant and anticoagulant activity is the challenging part in cases of radical prostatecomy of factor XI deficiency. Case Report: A 67-year-old patient is presented with organ confined intermediate-risk prostate cancer. Prolonged bleeding after tooth extraction and prostate biopsy indicated assessment of hemostatic system. Laboratory tests revealed factor XI deficiency. Successful laparoscopic extraperitoneal radical prostatectomy and bilateral pelvic lymphadenectomy was performed with low amount of blood loss. Recombinant activated coagulation factor VII was administered to prevent perioperative bleeding. The postoperative period was uneventful, no complications were observed. Conclusion: Despite the high risk of hemorrhage, laparoscopic radical prostatectomy is a feasible procedure even in a patient with factor XI deficiency, providing that the patient receive adequate preparation and a meticulously performed operation carried out by an experienced surgeon.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Factor XI deficiency Hemophilia Laparoscopy Radical prostatectomy
Megjelenés:	International Journal of Case Reports and Images 7 : 6 (2016), p. 374-377. -
További szerzők:	Benyó Mátyás (1982-) (urológus) Kiss Zoltán (1985-) (urológus) Flaskó Tibor (1960-) (urológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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