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001-es BibID:BIBFORM065371
Első szerző:Zierdt, Charles H.
Cím:Antibody Response to Blastocystis hominis Infections / Zierdt Charles H., Balint Nagy
Dátum:1993
ISSN:0003-4819
Megjegyzések:In our study, sera were obtained from 19 patients with symptomatic B. hominis infections. Two patients provided acute-phase sera and convalescent-phase sera. An indirect fluorescent antibody test (IFA) and an enzyme-linked immunosorbent assay (ELISA) were developed to search for antibodies against B. hominis. Both the IFA and ELISA techniques demonstrated specific IgG antibody against B. hominis (Table 1). The average titer was 1/268 by IFA and 1/405 by ELISA. The average titer for 50 normal (blood bank) sera was 1/24 by IFA, and all normal sera were negative by ELISA (1/50 was the threshold dilution). Titers for the two acute-phase sera were as follows: Patient 1, 1/200 by IFA and 1/100 by ELISA; Patient 2, 1/200 by IFA and 1/200 by ELISA. Titers for convalescent-phase sera were as follows: Patient 1, 1/800 by IFA and 1/800 by ELISA; Patient 2, 1/600 by IFA and 1/600 by ELISA. The decided increase in titer for these two patients indicates recent systemic infection with B. hominis. Inflammatory response to B. hominis has been said to be part of the pathology related to this infection [4]. The immune titers reported above are much higher than those reported for giardiasis, even though both parasites are noninvasive.
Tárgyszavak:Orvostudományok Klinikai orvostudományok hozzászólás
antibody
Blastocystis
hominis
infestion
response
Megjelenés:Annals Of Internal Medicine. - 118 : 12 (1993), p. 985-986. -
További szerzők:Nagy Bálint (1956-) (molekuláris genetikus)
Internet cím:DOI
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