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001-es BibID:	BIBFORM072233
Első szerző:	Liatsikos, Spyros A.
Cím:	Inherited thrombophilia and reproductive disorders / Liatsikos Spyros A., Tsikouras Panagiotis, Manav Bachar, Csorba Roland, Tempelhoff Georg Friedrich von, Galazios Georgios
Dátum:	2016
ISSN:	1309-0399 1309-0380
Megjegyzések:	Apart from its established role in the pathogenesis of venous thromboembolism (VTE), inherited thrombophilia has been proposed as a possible cause of pregnancy loss and vascular gestational complications. There is a lot of controversy in the literature on the relationship between inherited prothrombotic defects and these obstetric complications. This is a review of the literature on inherited thrombophilia and reproductive disorders. Factor V Leiden, prothrombin G20210A mutation, and protein S deficiency seem to be associated with late and recurrent early pregnancy loss, while their impact on other pregnancy complications is conflicting. No definite association has been established between protein C and antithrombin deficiency and adverse pregnancy outcome, primarily due to their low prevalence. Screening is suggested only for women with early recurrent loss or late pregnancy loss. Anticoagulant treatment during pregnancy should be considered for women with complications who were tested positive for thrombophilia.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Inherited thrombophilia Recurrent pregnancy loss Reproductive disorders
Megjelenés:	Journal of the Turkish German Gynecology Association 17 : 1 (2016), p. 45-50. -
További szerzők:	Tsikouras, Panagioti Manav, Bachar Csorba Roland (1972-) (szülész-nőgyógyász, gyermeknőgyógyász) Tempelhoff, Georg-Friedrich von Galazios, Georgios
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