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001-es BibID:	BIBFORM081581
Első szerző:	Sarzi-Puttini, Piercarlo
Cím:	Biosimilars vs originators : are they the same? / Sarzi-Puttini Piercarlo, Marotto Daniela, Caporali Roberto, Galeazzi Mauro, Atzeni Fabiola, Hamar Attila, Soós Boglárka, Szekanecz Zoltán
Dátum:	2019
ISSN:	1568-9972
Megjegyzések:	Biological drugs have revolutionised the treatment of rheumatic diseases, and the recent expiry of the patents for many biological agents has generated considerable interest among pharmaceutical companies and regulatory agencies, and led to the marketing of highly similar, low-cost versions known as biosimilars. The increasing trend of switching patients from effective but expensive drugs to their biosimilar counterparts will have a considerable economic impact in the coming years. However, although this will greatly extend patient access the latest treatments, clinicians, scientific societies and the patients themselves have expressed a number of concerns about their long-term efficacy and safety, as well as the consequences of potentially multiple switches being dictated by economic pressure rather than medical needs. Thee aim of this review is to evaluate the pros and cons of choosing biosimilars, and whether and when they can really be considered clinically equivalent to the original drugs.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Biosimilars Originators Extrapolation Interchangeability Switching
Megjelenés:	Autoimmunity Reviews. - 18 : 12 (2019), p. 1-5. -
További szerzők:	Marotto, Daniela Caporali, Roberto Galeazzi, Mauro Atzeni, Fabiola Hamar Attila Béla (1990-) (általános orvos) Soós Boglárka (1988-) (általános orvos) Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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